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Journal Articles

Links Between Complement Activation and Thrombosis

Wolfram Ruf, MD

Blood (2019) 134 (Supplement_1): SCI-40.

https://doi.org/10.1182/blood-2019-121113

Published: 2019

Journal Articles

Gpibα Engagement Induces Activation of Human Platelet TF and Association with Constitutively Platelet Surface-Bound FVIIa

Olga Panes, Biochemist, M. Francisca Becerra, Biochemist, Roger Valle, Biochemist, Claudia G Sáez, PhD, Patricia Hidalgo, MT, Jaime Pereira, MD, Jennifer Royce, Wolfram Ruf, MD, PhD, Diego Mezzano, MD

Blood (2019) 134 (Supplement_1): 2337.

https://doi.org/10.1182/blood-2019-126359

Published: 2019

Journal Articles

Macrophage Factor Xa Signaling Promotes Cancer Immune Evasion

Claudine Graf, MD PhD, Petra Wilgenbus, Maki Kitano, Stephan Macher-Göppinger, Wolfram Ruf, MD

Blood (2018) 132 (Supplement 1): 135.

https://doi.org/10.1182/blood-2018-99-119167

Published: 2018

Journal Articles

Integrin Alphav-beta3 on Podocytes Orchestrates Coagulation Protease Signaling through Protease-Activated Receptors

Madhusudhan Thati, PhD, Sanchita Ghosh, MS, Hongjie Wang, MD PhD, Wolfram Ruf, MD, Berend H. Isermann, MD

Blood (2018) 132 (Supplement 1): 137.

https://doi.org/10.1182/blood-2018-99-114566

Published: 2018

Journal Articles

Macrophage Protease-Activated Receptor 2 Regulates Fetal Liver Hematopoiesis in Mice

Mona Saffarzadeh, PhD, Wolfram Ruf, MD

Blood (2018) 132 (Supplement 1): 134.

https://doi.org/10.1182/blood-2018-99-112829

Published: 2018

Journal Articles

Inverse PAR1 Activity of Hematopoietic Stem Cells and BM Stromal Cells Mediates G-CSF-Induced Mobilization By Regulation of Nitric Oxide Generation

Neta Nevo, MD, Shiri Gur-Cohen, PhD, Orit Kollet, PhD, Francesca Avemaria, PhD, Seymen Avci, MSc, Tomer Itkin, PhD, Sagarika Chakrabarty, PhD, Tzila Zuckerman, MD, Benjamin Brenner, MD, Yona Nadir, MD, Irina Zaidman, MD, Myriam Ben Arush, MD, Charles Esmon, PhD, Wolfram Ruf, MD, Tsvee Lapidot, PhD

Blood (2016) 128 (22): 3370.

https://doi.org/10.1182/blood.V128.22.3370.3370

Published: 2016

Journal Articles

Proangiogenic TF-FVIIa-PAR2 Signaling Requires Matriptase-Independent Integrin Interaction

Andrea S Rothmeier, PhD, Jennifer Disse, PhD, Barbara M Mueller, PhD, Enbo Liu, Henrik Ostergaard, PhD, Wolfram Ruf, MD

Blood (2016) 128 (22): 3756.

https://doi.org/10.1182/blood.V128.22.3756.3756

Published: 2016

Journal Articles

Mechanism of Action of Hydroxychloroquine in the Antiphospholipid Syndrome

Nadine Müller-Calleja, PhD, Davit Manukyan, Wolfram Ruf, MD, Karl Lackner, MD

Blood (2016) 128 (22): 5023.

https://doi.org/10.1182/blood.V128.22.5023.5023

Published: 2016

Journal Articles

EPCR Guides Hematopoietic Stem Cells Homing to the Bone Marrow Independently of Niche Clearance

Blood (2016) 128 (22): 4538.

https://doi.org/10.1182/blood.V128.22.4538.4538

Published: 2016

Journal Articles

Coagulation Factor V Mediates Inhibition of Tissue Factor Signaling By Activated Protein C

Hartmut Weiler, Hai-Po Liang, PhD, Edward J Kerschen, PhD, Alireza Rezaie, PhD, Jose A. Fernandez, MD PhD, Rodney M. Camire, PhD, Wolfram Ruf, MD, John H. Griffin, PhD, Raffaele Toso, PhD

Blood (2015) 126 (23): 216.

https://doi.org/10.1182/blood.V126.23.216.216

Published: 2015

Journal Articles

Platelet-Localized FXI Promotes a Glycoprotein Ib Alpha Dependent Feedback Loop in Arterial Hypertension and Vascular Inflammation

Blood (2015) 126 (23): 2192.

https://doi.org/10.1182/blood.V126.23.2192.2192

Published: 2015

Journal Articles

EPCR/PAR1 Signaling Navigates Long-Term Repopulating Hematopoietic Stem Cell Bone Marrow Homing to Thrombomodulin-Enriched Blood Vessels

Shiri Gur Cohen, PhD, Tomer Itkin, PhD, Sagarika Chakrabarty, PhD, Claudine Graf, MD, Orit Kollet, PhD, Karin Golan, PhD, Alexander Kalinkovich, MDPhD, Charles T. Esmon, PhD, Wolfram Ruf, MD, Irit Sagi, PhD, Ayelet Erez, PhD, Tsvee Lapidot, PhD

Blood (2015) 126 (23): 33.

https://doi.org/10.1182/blood.V126.23.33.33

Published: 2015

Journal Articles

Distinct Mechanism of Anti-Hemophilic FVIII Activation By Nascent FXa in the Tissue Factor-FVIIa Coagulation Initiation Complex Resistant to FXa-Directed Inhibition

Yuichi Kamikubo, PhD, Grazia Loredana Mendolicchio, MD PhD, Antonella Zampolli, PhD, Patrizia Marchese, PhD, Andrew J. Gale, PhD, Sriram Krishnaswamy, PhD, Andras Gruber, MD, Lars Christian Petersen, Wolfram Ruf, MD, Zaverio M Ruggeri, MD

Blood (2014) 124 (21): 2803.

https://doi.org/10.1182/blood.V124.21.2803.2803

Published: 2014

Journal Articles

A Crucial Role for Caspase 1 in Thrombo-Inflammatory Microparticle Release

Andrea S Rothmeier, PhD, Patrizia Marchese, PhD, Christian Furlan-Freguia, PhD, Brian G. Petrich, PhD, Mark H. Ginsberg, MD, Zaverio M Ruggeri, MD, Wolfram Ruf, MD

Blood (2014) 124 (21): 2806.

https://doi.org/10.1182/blood.V124.21.2806.2806

Published: 2014

Journal Articles

Identification Of The Coagulation Factor VIIa Integrin Binding Site Essential For Pro-Angiogenic Tissue Factor Signaling

Andrea S Rothmeier, Ph.D., Barbara M Mueller, Ph.D., Henrik Ostergaard, Ph.D., Wolfram Ruf, MD

Blood (2013) 122 (21): 3566.

https://doi.org/10.1182/blood.V122.21.3566.3566

Published: 2013

Journal Articles

Tissue Factor On The Herpes Simplex Virus Type 1 Surface Enhances Infection In Vivo

Michael R Sutherland, PhD, Ayo Y Simon, DVM, PH.D., Iryna Shanina, Ph.D., Marc S Horwitz, Ph.D., Wolfram Ruf, MD, Ed L.G. Pryzdial, Ph. D.

Blood (2013) 122 (21): 2332.

https://doi.org/10.1182/blood.V122.21.2332.2332

Published: 2013

Journal Articles

EPCR Limits Nitric Oxide Levels, Mediating Human and Murine Stem Cell Adhesion and Retention In The Bone Marrow, By Conjugating PAR1 and CXCR4 Signaling

Shiri Gur Cohen, MSc, Tomer Itkin, PhD, Aya Ludin, DMD, PhD, Sagarika Chakrabarty, PhD, Orit Kollet, PhD, Karin Golan, MSc, Alexander Kalinkovich, MD, PhD, Eitan Wong, PhD, Ayelet Erez, MD PhD, Irit Sagi, PhD, Charles T Esmon, PhD, Wolfram Ruf, MD, Tsvee Lapidot, PhD

Blood (2013) 122 (21): 795.

https://doi.org/10.1182/blood.V122.21.795.795

Published: 2013

Journal Articles

Regulation Of Hematopoietic Stem Cell Trafficking By The Coagulation Pathway

Shiri Gur Cohen, MSc, Tomer Itkin, PhD, Orit Kollet, PhD, Sagarika Chakrabarty, PhD, Aya Ludin, DMD, PhD, Karin Golan, MSc, Alexander Kalinkovich, MD, PhD, Xin-Jiang Lu, PhD, Jeff R. Crosby, PhD, Brett P. Monia, PhD, Charles T Esmon, PhD, Wolfram Ruf, MD, Tsvee Lapidot, PhD

Blood (2013) 122 (21): 456.

https://doi.org/10.1182/blood.V122.21.456.456

Published: 2013

Journal Articles

Factor V Inhibits PAR2-Mediated Lethal Inflammation

Edward J Kerschen, PhD, Hai-Po Helena Liang, Jose A. Fernandez, MD, PhD, Raffaella Toso, PhD, Wolfram Ruf, MD, Rodney M. Camire, PhD, John H. Griffin, PhD, Hartmut Weiler, PhD

Blood (2012) 120 (21): 3360.

https://doi.org/10.1182/blood.V120.21.3360.3360

Published: 2012

Journal Articles

Thrombosis and Inflammation Are Coupled by a Common Thioredoxin Reductase Pathway Downstream of the P2×7 Receptor.

Andrea S Rothmeier, Ph.D., Christian Furlan-Freguia, Ph.D., Brian G. Petrich, PhD, Patrizia Marchese, PhD, Zaverio M. Ruggeri, MD, PhD, Mark H. Ginsberg, M.D., Wolfram Ruf, MD

Blood (2012) 120 (21): 2218.

https://doi.org/10.1182/blood.V120.21.2218.2218

Published: 2012

NARROW

Links Between Complement Activation and Thrombosis

Gpibα Engagement Induces Activation of Human Platelet TF and Association with Constitutively Platelet Surface-Bound FVIIa

Macrophage Factor Xa Signaling Promotes Cancer Immune Evasion

Integrin Alphav-beta3 on Podocytes Orchestrates Coagulation Protease Signaling through Protease-Activated Receptors

Macrophage Protease-Activated Receptor 2 Regulates Fetal Liver Hematopoiesis in Mice

Inverse PAR1 Activity of Hematopoietic Stem Cells and BM Stromal Cells Mediates G-CSF-Induced Mobilization By Regulation of Nitric Oxide Generation

Proangiogenic TF-FVIIa-PAR2 Signaling Requires Matriptase-Independent Integrin Interaction

Mechanism of Action of Hydroxychloroquine in the Antiphospholipid Syndrome

EPCR Guides Hematopoietic Stem Cells Homing to the Bone Marrow Independently of Niche Clearance

Coagulation Factor V Mediates Inhibition of Tissue Factor Signaling By Activated Protein C

Platelet-Localized FXI Promotes a Glycoprotein Ib Alpha Dependent Feedback Loop in Arterial Hypertension and Vascular Inflammation

EPCR/PAR1 Signaling Navigates Long-Term Repopulating Hematopoietic Stem Cell Bone Marrow Homing to Thrombomodulin-Enriched Blood Vessels

Distinct Mechanism of Anti-Hemophilic FVIII Activation By Nascent FXa in the Tissue Factor-FVIIa Coagulation Initiation Complex Resistant to FXa-Directed Inhibition

A Crucial Role for Caspase 1 in Thrombo-Inflammatory Microparticle Release

Identification Of The Coagulation Factor VIIa Integrin Binding Site Essential For Pro-Angiogenic Tissue Factor Signaling

Tissue Factor On The Herpes Simplex Virus Type 1 Surface Enhances Infection In Vivo

EPCR Limits Nitric Oxide Levels, Mediating Human and Murine Stem Cell Adhesion and Retention In The Bone Marrow, By Conjugating PAR1 and CXCR4 Signaling

Regulation Of Hematopoietic Stem Cell Trafficking By The Coagulation Pathway

Factor V Inhibits PAR2-Mediated Lethal Inflammation

Thrombosis and Inflammation Are Coupled by a Common Thioredoxin Reductase Pathway Downstream of the P2×7 Receptor.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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