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Valentina Botti, PhD
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Journal Articles

High-Resolution Binding Atlas of U2AF1 Mutants Uncovers New Complexity in Splicing Alterations and Kinetics in Myeloid Malignancies

Giulia Biancon, PhD, Poorval Joshi, PhD, Torben Hunck, Josh Zimmer, MS, Yimeng Gao, PhD, Martin Machyna, PhD, Valentina Botti, PhD, Ashley Qin, Gabriella Viero, PhD, Nils Neuenkirchen, PhD, Ashley Taylor, Rana Gbyli, MS, Amisha Patel, MS, Anastasia Ardasheva, BS, Xiaoying Fu, MD, Haifan Lin, PhD, Matthew D Simon, PhD, Karla M Neugebauer, PhD, Toma Tebaldi, PhD, Stephanie Halene, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 3–4.
https://doi.org/10.1182/blood-2020-142854
Published: 2020
Journal Articles

U2AF1 Driver Mutations in Hematopoietic Disorders Alter but Do Not Abrogate RNA Binding and Enlighten Structural Dependencies of the U2AF-RNA Complex

Giulia Biancon, PhD, Poorval Joshi, PhD, Torben Hunck, Yimeng Gao, PhD, Valentina Botti, PhD, Ashley Qin, Mukhtar Sadykov, MD, Xiaman Wang, MD PhD, Gabriella Viero, PhD, Nils Neuenkirchen, PhD, Ashley Taylor, Jane Huang, BS, Anastasia Ardasheva, BS, Xiaoying Fu, MD, Haifan Lin, PhD, Manoj M Pillai, MD, Clara L Kielkopf, PhD, Karla M Neugebauer, PhD, Toma Tebaldi, PhD, Stephanie Halene, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1230.
https://doi.org/10.1182/blood-2019-130759
Published: 2019