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Journal Articles

Endothelial Cell Protein C Receptor-Mediated Redistribution and Tissue-Level Accumulation of Pharmacologically Administered Recombinant Human Factor VIIa

Curtis A Clark, Rit Vatsyayan, Ph.D., Ramakrishnan Gopalakrishnan, Ph.D., Charles T Esmon, Ulla Hedner, MD, PhD, Usha R Pendurthi, Ph.D., L. Vijaya Mohan Rao, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 532.
https://doi.org/10.1182/blood.V118.21.532.532
Published: 2011
Journal Articles

Interaction of Factor VIIa with Endothelial Cell Protein C Receptor: Differences Between the Human and Mouse Systems

Prosenjit Sen, Ph.D., Curtis A Clark, Ramakrishnan Gopalakrishnan, Ph.D., Ulla Hedner, MD, PhD, Charles T Esmon, Usha R Pendurthi, Ph.D., L. Vijaya Mohan Rao, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 1181.
https://doi.org/10.1182/blood.V118.21.1181.1181
Published: 2011
Journal Articles

Characterizing the Effects of NN1731 and rFVIIa In Severe Hemophilia Patients with a Poor Laboratory Response to In Vivo Dosing of rFVIIa 90 μ g/Kg

Donald F Brophy, Pharm.D., Erika J Martin, MT(ASCP), John Christian Barrett, MD, Jan G Kuhn, RN, Melinda Nolte, RN, Ulla Hedner, MD, PhD, Mirella Ezban, Ph.D.
Journal: Blood
Blood (2010) 116 (21): 4414.
https://doi.org/10.1182/blood.V116.21.4414.4414
Published: 2010
Journal Articles

Evaluation of Clotting Parameters in a Patient with Hemophilia A and Inhibitors Who Has a Poor Clinical Response to Standard Dose rFVIIa.

Marcus E. Carr, Jr., MD, PhD, Erika J Martin, MT(ASCP), John Christian Barrett, MD, Mindy Nolte, RN, Janice Kuhn, RN, Mirella Ezban, PhD, Ulla Hedner, MD, PhD, Donald Brophy
Journal: Blood
Blood (2009) 114 (22): 4440.
https://doi.org/10.1182/blood.V114.22.4440.4440
Published: 2009
Journal Articles

Bio-Distribution of Recombinant Factor VIIa: A Possible Explanation for the Hemostatic Effect of rFVIIa in Prophylaxis.

Ramakrishnan Gopalakrishnan, PhD, Ulla Hedner, MD, PhD, Samit Ghosh, PhD, Ramesh Nayak, PhD, Usha Pendurthi, PhD, L. Vijaya Mohan Rao, PhD
Journal: Blood
Blood (2009) 114 (22): 3480.
https://doi.org/10.1182/blood.V114.22.3480.3480
Published: 2009
Journal Articles

Differences in Global Hemostasis Following rFVIIa Dosing: A Focus On Responders Versus Poor Responders.

Donald Brophy, Erika Martin, MT, (ASCP), John Christian Barrett, MD, Mindy Nolte, RN, Janice Kuhn, RN, Marcus E. Carr, Jr., MD, PhD, Mirella Ezban, PhD, Ulla Hedner, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 3485.
https://doi.org/10.1182/blood.V114.22.3485.3485
Published: 2009
Journal Articles

Formation of FVIIa-Antithrombin Complexes After Administration of rFVIIa to Hemophilia Patients.

Mirella Ezban, PhD, Erika Martin, MT, (ASCP), John Christian Barrett, MD, Janice Kuhn, RN, Mindy Nolte, Hermann Pelzer, Henrik Agerso, Lars Christian Petersen, Ulla Hedner, MD, PhD, Marcus E. Carr, Jr., MD, PhD, Donald Brophy, Pharm.D.
Journal: Blood
Blood (2009) 114 (22): 1295.
https://doi.org/10.1182/blood.V114.22.1295.1295
Published: 2009
Journal Articles

Restoring Initial Thrombin Generation Does Not Normalize Cutaneous Wound Healing in Hemophilia B.

Anna G. McDonald, BS, Maureane Hoffman, MD, PhD, Ulla Hedner, MD, Harold R. Roberts, MD, Dougald M. Monroe, PhD
Journal: Blood
Blood (2006) 108 (11): 1030.
https://doi.org/10.1182/blood.V108.11.1030.1030
Published: 2006
Journal Articles

A Variant of Recombinant Factor VIIa with Enhanced Procoagulant and Antifibrinolytic Activities in a Model of Hemophilia.

Alisa S. Wolberg, PhD, Egon Persson, PhD, Ulla Hedner, MD, Mirella Ezban, PhD, Geoffrey A. Allen, MD
Journal: Blood
Blood (2006) 108 (11): 767.
https://doi.org/10.1182/blood.V108.11.767.767
Published: 2006
Journal Articles

Enhanced Fibrin Clot Formation and Stability with a Superactive Analog of Factor VIIa in an In Vitro Model of Hemophilia.

Alisa S. Wolberg, PhD, Mirella Ezban, PhD, Ulla Hedner, MD, Egon Persson, PhD
Journal: Blood
Blood (2005) 106 (11): 4056.
https://doi.org/10.1182/blood.V106.11.4056.4056
Published: 2005
Journal Articles

Delayed Wound Healing in Hemophilia B Mice.

Maureane Hoffman, MD, PhD, Angie Lenkowski, Jacqueline Brock, Ulla Hedner, MD, Dougald M. Monroe, PhD
Journal: Blood
Blood (2005) 106 (11): 3199.
https://doi.org/10.1182/blood.V106.11.3199.3199
Published: 2005