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Tun-Kiat Ko, PhD
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Journal Articles

The Genomic and Epigenomic Landscapes of Blast Crisis Transformation in Chronic Myeloid Leukemia

S. Tiong Ong, MD, Thushangi Pathiraja, PhD, Asif Javed, PhD, Xin Xuan Sheila Soh, Simeen Malik, PhD, Joanna H.J. Tan, Tun Kiat Ko, PhD, Charles Chuah, Naoto Takahashi, MD, PhD, Ravi Bhatia, MD, King Pan Ng, PhD, Wee Joo Chng, MD PhD, Chandana Tennakoon, PhD, Qiangze Hoi, Peiyong Guan, Audrey S.M. Teo, Wah Heng Lee, PhD, Patrick Tan, MD PhD, Win Kin Sung, PhD, Pauline Ng, PhD, Axel Hillmer, PhD
Journal: Blood
Blood (2015) 126 (23): 3737.
https://doi.org/10.1182/blood.V126.23.3737.3737
Published: 2015
Journal Articles

Functional Analysis of the CML Blast Crisis Transcriptome and Epigenome Using Crispr-CAS9 and Pharmacologic Approaches

Tun Kiat Ko, PhD, Xin Xuan Sheila Soh, Willie Yu, PhD, Peter S. Winter, Thushangi Pathiraja, PhD, Asif Javed, PhD, Simeen Malik, PhD, Joanna H.J. Tan, Charles Chuah, MD PhD, Naoto Takahashi, MD, PhD, Ravi Bhatia, MD, Wee Joo Chng, MD PhD, Peter Valent, MD, Sabine Cerny-Reiterer, DVM, King Pan Ng, PhD, Chandana Tennakoon, PhD, Qiangze Hoi, Peiyong Guan, Audrey S.M. Teo, Wah Heng Lee, PhD, Patrick Tan, MD PhD, Win Kin Sung, PhD, Pauline Ng, PhD, Axel Hillmer, PhD, Kris C. Wood, PhD, Steve Rozen, PhD, S. Tiong Ong, MD
Journal: Blood
Blood (2015) 126 (23): 2764.
https://doi.org/10.1182/blood.V126.23.2764.2764
Published: 2015
Journal Articles

The BIM Deletion Polymorphism: A Paradigm Of a Permissive Interaction Between Germline and Acquired TKI Resistance Factors In Chronic Myeloid Leukemia

Tun Kiat Ko, PhD, Charles Chuah, MD, John W.J. Huang, King-Pan Ng, PhD, S. Tiong Ong, MD
Journal: Blood
Blood (2013) 122 (21): 3977.
https://doi.org/10.1182/blood.V122.21.3977.3977
Published: 2013
Journal Articles

The BCL-2 Inhibitor ABT-199 Enhances Imatinib-Induced Cell Death In Chronic Phase CML Progenitors

Tun Kiat Ko, PhD, Charles Chuah, MD, John Huang, King-Pan Ng, PhD, S. Tiong Ong, MD
Journal: Blood
Blood (2013) 122 (21): 3978.
https://doi.org/10.1182/blood.V122.21.3978.3978
Published: 2013
Journal Articles

A Common Deletion Polymorphism in the BIM Gene Contributes to Intrinsic Imatinib Resistance in Chronic Myelogenous Leukemia

Axel M Hillmer, PhD, King-Pan Ng, PhD, Charles Chuah, MBChB, FRCPE, MD, Wen Chun Juan, B.Sc, Tun-Kiat Ko, PhD, Audrey S.M. Teo, M.Sc, Pramila N Ariyaratne, M.Sc, Naoto Takahashi, MD, PhD, Kenichi Sawada, MD, PhD, Yao Fei, M.Sc, Wah Heng Lee, PhD, Weijie Huang, B.Sc, John C Allen, Jr., PhD, Xing Yi Woo, PhD, Niranjan Nagarajan, PhD, Vikrant Kumar, PhD, Anbupalam Thalamuthu, PhD, Wan Ting Poh, B.S, Ai Leen Ang, MBBS, MMed, (Internal, Medicine), Hae Tha Mya, M.B.B.S, Gee Fung How, PhD, Li Yi Yang, B.Sc, Liang Piu Koh, M.B.B.S, Veera S Nadarajan, M.B.B.S, Wee-Joo Chng, M.B.Ch.B, Hein Than, M.B.B.S, Lay Cheng Lim, MD, Yeow-Tee Goh, MBBS, MMed, Markus M Nöthen, M.D, Tien Y Wong, M.D, PhD, Atif Shahab, PhD, Xiaoan Ruan, PhD, Valère Cacheux-Rataboul, PhD, Wing-Kin Sung, PhD, Yijun Ruan, PhD, S. Tiong Ong, M.A., M.B.B.Ch., M.R.C.P., (UK)
Journal: Blood
Blood (2011) 118 (21): 1666.
https://doi.org/10.1182/blood.V118.21.1666.1666
Published: 2011