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Toshihito Hirai, MD PhD
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Journal Articles

RNA and TCR Sequencing Shed Light on Mechanisms of Treg Suppression in a Murine Model of Acute GvHD

Juliane K. Lohmeyer, MD, Toshihito Hirai, MD PhD, Mustafa Turkoz, PhD, Natalie Koehler, PhD, Jeanette Baker, Stephane Buhler, PhD, Jean Villard, MD PhD, Xuhuai Ji, MD PhD, Federico Simonetta, MD PhD, Robert S. Negrin, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30.
https://doi.org/10.1182/blood-2020-137220
Published: 2020
Journal Articles

Molecular Imaging of Chimeric Antigen Receptor T Cells By ICOS-Immunopet

Federico Simonetta, MD PhD, Israt S. Alam, PhD, Juliane K. Lohmeyer, MD, Bita Sahaf, PhD, Zinaida Good, PhD, Weiyu Chen, PhD, Zunyu Xiao, MD PhD, Toshihito Hirai, MD PhD, Lukas Scheller, MD, Pujan Engels, M.Sc., Ophir Vermesh, MD PhD, Elise Robinson, Tom Haywood, PhD, Ataya Sathirachindra, Jeanette Baker, Meena B. Malipatlolla, Liora M. Schultz, MD, Jay Y. Spiegel, MDFRCPC, Jason T. Lee, PhD, David B. Miklos, MD PhD, Crystal L. Mackall, MD, Sanjiv S. Gambhir, MD PhD, Robert S. Negrin, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–6.
https://doi.org/10.1182/blood-2020-136331
Published: 2020
Journal Articles

Allogeneic Chimeric Antigen Receptor-Invariant Natural Killer T Cells Exert Both Direct and Indirect Antitumor Effects through Host CD8 T Cell Cross-Priming

Federico Simonetta, MD PhD, Toshihito Hirai, MD PhD, Juliane K. Lohmeyer, MD, Kristina Maas-Bauer, MD, Maite Alvarez, PhD, Arielle S. Wenokur, Jeanette Baker, Amin Aalipour, PhD, Samuel Haile, PhD, Crystal L. Mackall, MD, Robert S. Negrin, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 867.
https://doi.org/10.1182/blood-2019-122515
Published: 2019
Journal Articles

iNKT Cell Stimulation with Liposomal Alpha/Gal/Cer Amplifies Proliferation of Adoptively Transferred Regulatory T Cells In Vivo and Reduces GvHD

Toshihito Hirai, MD PhD, Federico Simonetta, MD PhD, Kristina Maas-Bauer, MD, Melissa Mavers, MD PhD, Jeanette Baker, Robert S. Negrin, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4519.
https://doi.org/10.1182/blood-2018-99-109836
Published: 2018
Journal Articles

Tracking T Cell Activation By OX40 Immuno-PET: A Novel Strategy for Imaging of Graft Versus Host Disease

Federico Simonetta, MD PhD, Israt S. Alam, PhD, Aaron T. Mayer, Surya Murty, Ophir Vermesh, MD PhD, Toshihito Hirai, MD PhD, Tomomi Nobashi, MD, Kenneth Lau, Sanjiv S. Gambhir, MD PhD, Robert S. Negrin, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4527.
https://doi.org/10.1182/blood-2018-99-116483
Published: 2018
Journal Articles

Invariant Natural Killer T Cell Subsets Have Diverse Functions: iNKT2 and iNKT17 Protect from Graft-Versus-Host-Disease, Whereas iNKT1 Have Antitumor Potential

Kristina Maas-Bauer, MD, Federico Simonetta, MD PhD, Toshihito Hirai, MD PhD, Arielle Wenokur, Furqan Fazal, PhD, Neeraja Kambham, MD, Jessica Ribado, Melissa Mavers, MD PhD, Jeanette Baker, Ami S. Bhatt, MD PhD, Howard Y. Chang, MD PhD, Robert S. Negrin, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 475.
https://doi.org/10.1182/blood-2018-99-113673
Published: 2018
Journal Articles

IL-2 Plus IL-15 Leads to Enhanced Ex Vivo Expansion of Human Invariant Natural Killer T Cells

Melissa Mavers, MD, Federico Simonetta, MD PhD, Alexander W. Lee, Toshihito Hirai, MD PhD, Kristina Maas-Bauer, MD, Jeanette Baker, PhD, Maite Alvarez, PhD, Mustafa Turkoz, PhD, Everett H. Meyer, MD PhD, Robert S. Negrin, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3199.
https://doi.org/10.1182/blood.V130.Suppl_1.3199.3199
Published: 2017
Journal Articles

Treatment of Donors with Liposomal Alpha-Galactosylceramide Results in the In Vivo Expansion of Invariant Natural Killer T Cells and Reduced Incidence of Acute Graft Versus Host Disease

Toshihito Hirai, MD PhD, Federico Simonetta, MD PhD, Jeanette Baker, PhD, Kristina Maas-Bauer, MD, Musutafa Turkoz, Maite Alvarez, PhD, Melissa Mavers, MD, Robert S. Negrin, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1896.
https://doi.org/10.1182/blood.V130.Suppl_1.1896.1896
Published: 2017