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Tomasz Rzymski, PhD
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Journal Articles

PIM Kinase Inhibition Decreases the Proangiogenic Properties of Multiple Myeloma Cells and Affects the Metabolic State of the Vascular Endothelium

Filip Garbicz, MD, Anna Szumera-Ciećkiewicz, MD PhD, Joanna Barankiewicz, MD, Dorota Komar, PhD, Michał Pawlak, PhD, Sonia Dębek, MSc, Aleksandra Matrejek, MSc, Thorsten Stuehmer, PhD, Aleksander Salomon-Perzynski, MD, Agata Malenda, MD PhD, Krzysztof Brzózka, PhD, Tomasz Rzymski, PhD, Andrea Massimiliano Tomirotti, PhD, Ewa Lech-Marańda, MD PhD, Monika Prochorec-Sobieszek, MD PhD, Maciej Szydlowski, PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
https://doi.org/10.1182/blood-2020-134979
Published: 2020
Journal Articles

CDK8 Inhibitors Induce Transcriptional Reprogramming of AML Cells Associated with Differentiation

Milena Mazan, PhD, Marion Chapellier, PhD, Marcus Järås, PhD, Michal Mikula, MD PhD, Eliza Majewska, PhD, Katarzyna Wiklik, PhD, Michal Combik, PhD, Aniela Golas, PhD, Magdalena Masiejczyk, MSc, Elzbieta Fiedor, MSc, Federico Malusa, MSc, Przemyslaw Juszczynski, Prof., MD PhD, Magdalena Cybulska, DVM, Maciej Mikulski, PhD, Jerzy Ostrowski, Prof., MD PhD, Pawel Chrom, MD PhD, Krzysztof Brzózka, PhD, Tomasz Rzymski, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3774.
https://doi.org/10.1182/blood-2019-128073
Published: 2019
Journal Articles

SEL120 - a First-in-Class CDK8/19 Inhibitor As a Novel Option for the Treatment of Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome - Data from Preclinical Studies and Introduction to a Phase Ib Clinical Trial

Gautam M. Borthakur, MD, William B. Donnellan, MD, Scott R. Solomon, MD, Camille Abboud, MD, Aziz Nazha, MD, Milena Mazan, PhD, Michal Mikula, MD PhD, Eliza Majewska, PhD, Katarzyna Wiklik, PhD, Aniela Golas, PhD, Marcus Järås, PhD, Marion Chapellier, PhD, Anna Polak, PhD, Arkadiusz Bialas, PhD, Renata Windak, PhD, Jerzy Ostrowski, Prof., MD PhD, Przemyslaw Juszczynski, Prof., MD PhD, Pawel Chrom, MD PhD, Tomasz Rzymski, PhD, Krzysztof Brzózka, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2651.
https://doi.org/10.1182/blood-2019-127835
Published: 2019
Journal Articles

CDK8 Inhibitor SEL120-34A Has Therapeutic Efficacy in Murine and Human Acute Myeloid Leukemia Models

Marion Chapellier, PhD, Jun Chen, MD PhD, Carl Sandén, PhD, Milena Mazan, PhD, Eliza Majewska, Katarzyna Wiklik, PhD, Michal Combik, PhD, Magdalena Masiejczyk, MSc, Elzbieta Fiedor, Marta Obacz, Anna Polak, Arkadiusz Bialas, Paulina Chesy, Ewelina Gabor-Worwa, Przemyslaw Juszczynski, MD PhD, Krzysztof Brzózka, PhD, Tomasz Rzymski, PhD, Thoas Fioretos, MD PhD, Johan Flygare, MD PhD, Marcus Jaras, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1520.
https://doi.org/10.1182/blood-2018-99-111859
Published: 2018
Journal Articles

Small Molecule Screens Identify CDK8-Inhibitors As Candidate Diamond-Blackfan Anemia Drugs

Jun Chen, MD PhD, Kavitha Siva, PhD, Tomasz Rzymski, PhD, Lars Johansson, Thomas Lundbäck, Lorena Nunez Villacis, Fredrik Ek, PhD, Bingrui Wang, Amee J George, PhD, Yang Wan, Lihong Shi, Melissa IIsley, Agatheeswaran Subramaniam, PhD, Mayur Jain, PhD, Shubhranshu Debnath, PhD, Abdul Ghani Alattar, Hanna Axelsson, Milena Mazan, PhD, Eliza Majewska, Ulf R. Tedgard, MD PhD, Marcin W. Wlodarski, MD PhD, Anna-Lena Gustavsson, Roger Olsson, Michal Mikula, Xiaofan Zhu, PhD, Krzysztof Brzózka, PhD, Ross Hannan, PhD, Johan Flygare, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 753.
https://doi.org/10.1182/blood-2018-99-114570
Published: 2018