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Thomas P. Loughran, MD
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Journal Articles

STAT3 Mediates C6-Ceramide-Induced Cell Death in Chronic Lymphocytic Leukemia

Ushma Atul Doshi, Thomas P. Loughran, MD, Mark Kester
Journal: Blood
Blood (2014) 124 (21): 4694.
https://doi.org/10.1182/blood.V124.21.4694.4694
Published: 2014
Journal Articles

Aberrant NK Receptor Signaling Associated with Large Granular Lymphoycte Leukemia and Primary Pulmonary Hypertension.

P.K. Epling-Burnette, PhD, Xianhong Chen, Junmin Zhou, Fanqi Bai, MD, Sokol Lubomir, MD, Edna Ku, MD, Jeffrey S. Painter, BS, Zou JianXiang, MD, Todd D. Edwards, MD, Djeu Y. Julie, PhD, Moscinski C. Lynn, MD, Thomas P. Loughran, MD, Sheng Wei, MD
Journal: Blood
Blood (2007) 110 (11): 4704.
https://doi.org/10.1182/blood.V110.11.4704.4704
Published: 2007
Journal Articles

Elevated Fas Ligand and BA21 Serorecognition as Disease Correlates in Bone Marrow Failure Disorders: Taking Advantage of the LGL Leukemia Model.

Susan B. Nyland, PhD, David Cuthbertson, MS, Thomas P. Loughran, MD
Journal: Blood
Blood (2007) 110 (11): 4274.
https://doi.org/10.1182/blood.V110.11.4274.4274
Published: 2007
Journal Articles

First Clinical Report of Tipifarnib for the Treatment of T-Large Granular Lymphocyte (LGL) Leukemia.

P.K. Epling-Burnette, PhD, Lubomir Sokol, MD, Lynn Moscinski, MD, Magda Elkabani, MD, Fanqi Bai, MD, Michelle Blaskovich, BS, JianXiang Zou, MD, Jeffrey S. Painter, BS, Said Sebti, PhD, Thomas P. Loughran, MD
Journal: Blood
Blood (2007) 110 (11): 3132.
https://doi.org/10.1182/blood.V110.11.3132.3132
Published: 2007
Journal Articles

Constitutive Activation of Ras and Mitogen-Activated Protein Kinase (MAPK/ERK) in LGL Leukemia Unrelated to Activating Mutations in N and KRas Genes.

Jeffrey S. Painter, BS, Angela Costellanos, Fanqi Bai, MD, Sheng Wei, MD, Thomas P. Loughran, MD, P.K. Epling-Burnette, PhD
Journal: Blood
Blood (2007) 110 (11): 3180.
https://doi.org/10.1182/blood.V110.11.3180.3180
Published: 2007
Journal Articles

Th2 Polarization Induced by the Farnesyltransferase Inhibitor Tipifarnib (Zarnestra®, R115777) through Suppression of T-bet.

Fanqi Bai, MD, J.-X. Zou, MD, Sheng Wei, MD, Jeffrey S. Painter, BS, Michelle Blaskovich, Bs, Said Sebti, PhD, Thomas P. Loughran, MD, P.K. Epling-Burnette, PhD
Journal: Blood
Blood (2007) 110 (11): 1331.
https://doi.org/10.1182/blood.V110.11.1331.1331
Published: 2007
Journal Articles

Elevated Serum Ras Levels in Patients with LGL Leukemia.

Erin M. Nelli, DO, Thomas P. Loughran, MD, Kim Leitzel, MSc, Suhail M. Ali, MD, Lawrence Demers, PhD, Walter P. Carney, PhD, Peter J. Hamer, MA, Allan Lipton, MD
Journal: Blood
Blood (2006) 108 (11): 4457.
https://doi.org/10.1182/blood.V108.11.4457.4457
Published: 2006
Journal Articles

Complex Immunosuppressive Action of Farnesyltransferase Inhibitor (FTI) R115777 (Tipifarnib, Zarnestra®) with Induction of Apoptosis in T Cells from Patients with Large Granular Lymphocyte (LGL) Leukemia.

Fanqi Bai, MD, JianXiang Zou, MD, Jun Yang, MD, Edna Ku, MD,PhD, Sheng Wei, MD, Thomas P. Loughran, MD, P.K. Epling-Burnette, PhD
Journal: Blood
Blood (2006) 108 (11): 4960.
https://doi.org/10.1182/blood.V108.11.4960.4960
Published: 2006
Journal Articles

T Large Granular Lymphocyte (LGL) Leukemia Characterized by Expansion of Terminal CD3+/CD8+/CD62L−/CD45RA+ Effector Memory T Cells.

JianXiang Zou, MD, Jeffrey S. Painter, BS, Fanqi Bai, MD, Thomas P. Loughran, MD, P.K. Epling-Burnette, PhD
Journal: Blood
Blood (2006) 108 (11): 4962.
https://doi.org/10.1182/blood.V108.11.4962.4962
Published: 2006
Journal Articles

In Addition to Immune Suppression, There Is Defective Maturation of CD34 + Cells in Patients with Natural Killer-Lymphoproliferative Disease of Granular Lymphcoytes (NK-LDGL).

P.K. Epling-Burnette, PhD, Fanqi Bai, MD, Jeffrey S. Painter, Thomas P. Loughran, MD
Journal: Blood
Blood (2005) 106 (11): 2404.
https://doi.org/10.1182/blood.V106.11.2404.2404
Published: 2005