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Journal Articles

STAT3 Mediates C6-Ceramide-Induced Cell Death in Chronic Lymphocytic Leukemia

Ushma Atul Doshi, Thomas P. Loughran, MD, Mark Kester

Blood (2014) 124 (21): 4694.

https://doi.org/10.1182/blood.V124.21.4694.4694

Published: 2014

Journal Articles

First Clinical Report of Tipifarnib for the Treatment of T-Large Granular Lymphocyte (LGL) Leukemia.

P.K. Epling-Burnette, PhD, Lubomir Sokol, MD, Lynn Moscinski, MD, Magda Elkabani, MD, Fanqi Bai, MD, Michelle Blaskovich, BS, JianXiang Zou, MD, Jeffrey S. Painter, BS, Said Sebti, PhD, Thomas P. Loughran, MD

Blood (2007) 110 (11): 3132.

https://doi.org/10.1182/blood.V110.11.3132.3132

Published: 2007

Journal Articles

Constitutive Activation of Ras and Mitogen-Activated Protein Kinase (MAPK/ERK) in LGL Leukemia Unrelated to Activating Mutations in N and KRas Genes.

Jeffrey S. Painter, BS, Angela Costellanos, Fanqi Bai, MD, Sheng Wei, MD, Thomas P. Loughran, MD, P.K. Epling-Burnette, PhD

Blood (2007) 110 (11): 3180.

https://doi.org/10.1182/blood.V110.11.3180.3180

Published: 2007

Journal Articles

Th2 Polarization Induced by the Farnesyltransferase Inhibitor Tipifarnib (Zarnestra®, R115777) through Suppression of T-bet.

Fanqi Bai, MD, J.-X. Zou, MD, Sheng Wei, MD, Jeffrey S. Painter, BS, Michelle Blaskovich, Bs, Said Sebti, PhD, Thomas P. Loughran, MD, P.K. Epling-Burnette, PhD

Blood (2007) 110 (11): 1331.

https://doi.org/10.1182/blood.V110.11.1331.1331

Published: 2007

Journal Articles

Elevated Fas Ligand and BA21 Serorecognition as Disease Correlates in Bone Marrow Failure Disorders: Taking Advantage of the LGL Leukemia Model.

Susan B. Nyland, PhD, David Cuthbertson, MS, Thomas P. Loughran, MD

Blood (2007) 110 (11): 4274.

https://doi.org/10.1182/blood.V110.11.4274.4274

Published: 2007

Journal Articles

Aberrant NK Receptor Signaling Associated with Large Granular Lymphoycte Leukemia and Primary Pulmonary Hypertension.

P.K. Epling-Burnette, PhD, Xianhong Chen, Junmin Zhou, Fanqi Bai, MD, Sokol Lubomir, MD, Edna Ku, MD, Jeffrey S. Painter, BS, Zou JianXiang, MD, Todd D. Edwards, MD, Djeu Y. Julie, PhD, Moscinski C. Lynn, MD, Thomas P. Loughran, MD, Sheng Wei, MD

Blood (2007) 110 (11): 4704.

https://doi.org/10.1182/blood.V110.11.4704.4704

Published: 2007

Journal Articles

Elevated Serum Ras Levels in Patients with LGL Leukemia.

Erin M. Nelli, DO, Thomas P. Loughran, MD, Kim Leitzel, MSc, Suhail M. Ali, MD, Lawrence Demers, PhD, Walter P. Carney, PhD, Peter J. Hamer, MA, Allan Lipton, MD

Blood (2006) 108 (11): 4457.

https://doi.org/10.1182/blood.V108.11.4457.4457

Published: 2006

Journal Articles

Complex Immunosuppressive Action of Farnesyltransferase Inhibitor (FTI) R115777 (Tipifarnib, Zarnestra®) with Induction of Apoptosis in T Cells from Patients with Large Granular Lymphocyte (LGL) Leukemia.

Fanqi Bai, MD, JianXiang Zou, MD, Jun Yang, MD, Edna Ku, MD,PhD, Sheng Wei, MD, Thomas P. Loughran, MD, P.K. Epling-Burnette, PhD

Blood (2006) 108 (11): 4960.

https://doi.org/10.1182/blood.V108.11.4960.4960

Published: 2006

Journal Articles

T Large Granular Lymphocyte (LGL) Leukemia Characterized by Expansion of Terminal CD3+/CD8+/CD62L−/CD45RA+ Effector Memory T Cells.

JianXiang Zou, MD, Jeffrey S. Painter, BS, Fanqi Bai, MD, Thomas P. Loughran, MD, P.K. Epling-Burnette, PhD

Blood (2006) 108 (11): 4962.

https://doi.org/10.1182/blood.V108.11.4962.4962

Published: 2006

Journal Articles

In Addition to Immune Suppression, There Is Defective Maturation of CD34 + Cells in Patients with Natural Killer-Lymphoproliferative Disease of Granular Lymphcoytes (NK-LDGL).

P.K. Epling-Burnette, PhD, Fanqi Bai, MD, Jeffrey S. Painter, Thomas P. Loughran, MD

Blood (2005) 106 (11): 2404.

https://doi.org/10.1182/blood.V106.11.2404.2404

Published: 2005

NARROW

STAT3 Mediates C6-Ceramide-Induced Cell Death in Chronic Lymphocytic Leukemia

First Clinical Report of Tipifarnib for the Treatment of T-Large Granular Lymphocyte (LGL) Leukemia.

Constitutive Activation of Ras and Mitogen-Activated Protein Kinase (MAPK/ERK) in LGL Leukemia Unrelated to Activating Mutations in N and KRas Genes.

Th2 Polarization Induced by the Farnesyltransferase Inhibitor Tipifarnib (Zarnestra®, R115777) through Suppression of T-bet.

Elevated Fas Ligand and BA21 Serorecognition as Disease Correlates in Bone Marrow Failure Disorders: Taking Advantage of the LGL Leukemia Model.

Aberrant NK Receptor Signaling Associated with Large Granular Lymphoycte Leukemia and Primary Pulmonary Hypertension.

Elevated Serum Ras Levels in Patients with LGL Leukemia.

Complex Immunosuppressive Action of Farnesyltransferase Inhibitor (FTI) R115777 (Tipifarnib, Zarnestra®) with Induction of Apoptosis in T Cells from Patients with Large Granular Lymphocyte (LGL) Leukemia.

T Large Granular Lymphocyte (LGL) Leukemia Characterized by Expansion of Terminal CD3+/CD8+/CD62L−/CD45RA+ Effector Memory T Cells.

In Addition to Immune Suppression, There Is Defective Maturation of CD34 + Cells in Patients with Natural Killer-Lymphoproliferative Disease of Granular Lymphcoytes (NK-LDGL).

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American Society of Hematology

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American Society of Hematology

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