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Tamara M Leclercq
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Journal Articles

In Vitro Modeling of Ph-like ALL Fusions Identifies Novel Kinase-Domain Mutations As Mode of TKI-Resistance - Implications for Targeted Therapy

Kartini Asari, Susan L Heatley, PhD MD, Teresa Sadras, PhD, Tamara M Leclercq, PhD, Stephen Fitter, PhD, Chung Hoow Kok, PhD, Andrew C W Zannettino, PhD, Timothy P. Hughes, MD FRACP, FRCPA, MBBS, Deborah L White, PhD FFSc (RCPA)
Journal: Blood
Blood (2016) 128 (22): 3957.
https://doi.org/10.1182/blood.V128.22.3957.3957
Published: 2016
Journal Articles

High Peroxisome Proliferator-Activated Receptor-Gamma (PPARĪ³) Transcriptional Activity Reduces Active Influx of Imatinib and Kinase Inhibition in CML Cells

Jueqiong WANG, PhD, Chung Hoow Kok, PhD, Tamara M Leclercq, PhD, Verity A Saunders, BSc (Hons), Richard J D'Andrea, PhD, Timothy P. Hughes, MD MBBS, FRACP, FRCPA, Deborah L White, PhD FFSc (RCPA)
Journal: Blood
Blood (2015) 126 (23): 2770.
https://doi.org/10.1182/blood.V126.23.2770.2770
Published: 2015
Journal Articles

A 20 Gene Expression Signature That Predicts Early Molecular Response Failure in Chronic Phase CML Patients Treated with Frontline Imatinib

Chung Hoow Kok, PhD, Tamara M Leclercq, PhD, Dale Watkins, PhD, David T Yeung, BSc, MBBS, FRACP, FRCPA, Verity A Saunders, BSc (Hons), Deborah L White, PhD FFSc (RCPA), Timothy P. Hughes, MD MBBS, FRACP, FRCPA
Journal: Blood
Blood (2015) 126 (23): 596.
https://doi.org/10.1182/blood.V126.23.596.596
Published: 2015
Journal Articles

The Allosteric Inhibitor ABL001 Is Susceptible to Resistance in Vitro Mediated By Overexpression of the Drug Efflux Transporters ABCB1 and ABCG2

Laura N Eadie, PhD, Verity A Saunders, BSc (Hons), Tamara M Leclercq, PhD, Susan Branford, PhDFFSc (RCPA), Deborah L White, PhD FFSc (RCPA), Timothy P. Hughes, MD MBBS, FRACP, FRCPA
Journal: Blood
Blood (2015) 126 (23): 4841.
https://doi.org/10.1182/blood.V126.23.4841.4841
Published: 2015