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Journal Articles

Platelet Decrease and Efficacy of Platelet-Rich Plasma Return for Peripheral Blood Stem Cell Apheresis

Takahiro Shima, MD PhD, Teppei Sakoda, MD, Tomoko Henzan, MD, Yuya Kunisaki, MD PhD, Takahiro Maeda, MD PhD, Koichi Akashi, MD PhD, Toshihiro Miyamoto, MD PhD

Blood (2020) 136 (Supplement 1): 29–30.

https://doi.org/10.1182/blood-2020-142316

Published: 2020

Journal Articles

RUNX1 Deficiency Cooperates with SRSF2 Mutation to Further Disrupt RNA Splicing and Exacerbate Myelodysplastic Syndromes in Mouse Models

Yi-Jou Huang, BS, Ming Yan, PhD, Jia-Yu Chen, PhD, Liang Chen, PhD, Eunhee Kim, PhD, Takahiro Shima, MD PhD, Amanda G Davis, BS, Sayuri Miyauchi, DDS, PhD, Samuel A Stoner, Xiang-Dong Fu, PhD, Omar I Abdel-Wahab, MD, Dong-Er Zhang, PhD

Blood (2018) 132 (Supplement 1): 1796.

https://doi.org/10.1182/blood-2018-99-119104

Published: 2018

Journal Articles

CPSF1-Mediated Acute Myeloid Leukemia Fusion 3'UTR Alternation Is a Potential Therapeutic Target

Takahiro Shima, MD PhD, Amanda G Davis, Daniel T Johnson, Yu Kochi, MD, Sayuri Miyauchi, DDS, PhD, Samuel A Stoner, Junichiro Yuda, MD, Toshihiro Miyamoto, MD PhD, Jie-Hua Zhou, MD, Edward D. Ball, MD, Koichi Akashi, MD PhD, Dong-Er Zhang, PhD

Blood (2018) 132 (Supplement 1): 885.

https://doi.org/10.1182/blood-2018-99-119199

Published: 2018

Journal Articles

FIP1L1 Regulates Alternative Polyadenylation of Leukemia-Associated Genes in Acute Myeloid Leukemia

Amanda G Davis, BS, Takahiro Shima, MD PhD, Ruijia Wang, PhD, Dinghai Zheng, PhD, Bin Tian, PhD, Dong-Er Zhang, PhD

Blood (2018) 132 (Supplement 1): 3882.

https://doi.org/10.1182/blood-2018-99-119582

Published: 2018

Journal Articles

Hippo Kinase Inactivation Contributes to Del(20q) Malignancies and Cooperates with JAK2-V617F to Promote Myelofibrosis in Mice

Samuel A Stoner, Ming Yan, PhD, Katherine Liu, Takahiro Shima, MD PhD, Huan-You Wang, MD PhD, Kei-Ichiro Arimoto, PhD, Rafael Bejar, MD PhD, Catriona Jamieson, MD PhD, Kun-Liang Guan, PhD, Dong-Er Zhang, PhD

Blood (2018) 132 (Supplement 1): 99.

https://doi.org/10.1182/blood-2018-99-115591

Published: 2018

Journal Articles

RUNX1 Deficiency and SRSF2 Mutation Cooperate to Promote Myelodysplastic Syndrome Development

Yi-Jou Huang, BS, Ming Yan, PhD, Eunhee Kim, PhD, Amanda G Davis, BS, Takahiro Shima, MD PhD, Sayuri Miyauchi, DDS, PhD, Xiang-Dong Fu, PhD, Omar Abdel-Wahab, MD, Dong-Er Zhang, PhD

Blood (2017) 130 (Supplement 1): 119.

https://doi.org/10.1182/blood.V130.Suppl_1.119.119

Published: 2017

Journal Articles

Characterization of the Post-Transcriptional Regulation of AML1-ETO Expression in t(8;21) Leukemia Cells

Daniel T Johnson, BS, Takahiro Shima, MD PhD, Amanda G Davis, BS, Dong-Er Zhang, PhD

Blood (2017) 130 (Supplement 1): 3790.

https://doi.org/10.1182/blood.V130.Suppl_1.3790.3790

Published: 2017

Journal Articles

CPSF1 Regulates AML1-ETO Fusion Gene Polyadenylation and Stability in t(8;21) Acute Myelogenous Leukemia

Takahiro Shima, MD PhD, Amanda G Davis, Sayuri Miyauchi, DDS, PhD, Yu Kochi, MD, Daniel T Johnson, Samuel A Stoner, BS, Yuda Junichiro, MD, Toshihiro Miyamoto, MD PhD, Jie-Hua Zhou, MD, Edward D Ball, MD, Koichi Akashi, MD PhD, Dong-Er Zhang, PhD

Blood (2017) 130 (Supplement 1): 2498.

https://doi.org/10.1182/blood.V130.Suppl_1.2498.2498

Published: 2017

Journal Articles

Usp18 Is Required for Normal Stem Cell Maintenance

Kei-ichiro Arimoto, PhD, Yue Zhang, Ming Yan, PhD, Sayuri Miyauchi, DDS, PhD, Stephanie Weng, PhD, Samuel A. Stoner, Takahiro Shima, MD PhD, Yukiko Komeno, MD PhD, Kentson Lam, MD PhD, Dong-Er Zhang, PhD

Blood (2016) 128 (22): 3863.

https://doi.org/10.1182/blood.V128.22.3863.3863

Published: 2016

Journal Articles

Prior Use of Mogamulizumab to Allogenic Hematopoietic Stem Cell Transplantation Induces Severe Acute Graft-Versus-Host Disease

Blood (2015) 126 (23): 1940.

https://doi.org/10.1182/blood.V126.23.1940.1940

Published: 2015

Journal Articles

TIM-3 and Its Ligand, Galectin-9 Constitute a Pan-Myeloid Autocrine Loop to Develop and Maintain Malignant Stem Cells in Most Human Myeloid Leukemia

Yoshikane Kikushige, MD PhD, Junichiro Yuda, MD, Takahiro Shima, MD, Toshihiro Miyamoto, MD PhD, Koichi Akashi, MD PhD

Blood (2014) 124 (21): 835.

https://doi.org/10.1182/blood.V124.21.835.835

Published: 2014

Journal Articles

TIM-3, a Leukemia Stem Cell Marker, Plays a Role In Leukemic Transformation Through Autocrine Stimulatory Signaling By Its Ligand, Galectin-9

Yoshikane Kikushige, MD PhD, Junichiro Yuda, MD, Takahiro Shima, MD, Toshihiro Miyamoto, MD, Koichi Akashi, MD, PhD

Blood (2013) 122 (21): 4196.

https://doi.org/10.1182/blood.V122.21.4196.4196

Published: 2013

Journal Articles

Visualization Of Normal and Malignant Epigenetic Regulation In Hematopoiesis Utilizing Newly-Developed Histone Variant H3.3 Chipseq Analysis

Jun Odawara, MD, PhD, Kohta Miyawaki, MD, Junichiro Yuda, MD, Masayasu Hayashi, MD, Kazumitsu Maehara, PhD, Takahiro Shima, MD, Yoshikane Kikushige, MD, PhD, Yasuyuki Ohkawa, PhD, Koichi Akashi, MD, PhD

Blood (2013) 122 (21): 1189.

https://doi.org/10.1182/blood.V122.21.1189.1189

Published: 2013

Journal Articles

The Expansion Of CML Clones Initiates At The CMP Stage, and Is Associated With The Down-Regulation Of IRF8 and GFI1

Kohta Miyawaki, MD, Hirotake Kusumoto, MD, Tadafumi Iino, MD, Kentaro Kohno, MD, Hirofumi Tsuzuki, Takahiro Shima, MD, Yoshikane Kikushige, MD, PhD, Yojiro Arinobu, MD, PhD, Katsuto Takenaka, MD, PhD, Toshihiro Miyamoto, MD, Hiromi Iwasaki, MD, PhD, Koichi Akashi, MD, PhD

Blood (2013) 122 (21): 1477.

https://doi.org/10.1182/blood.V122.21.1477.1477

Published: 2013

Journal Articles

Fibrotic Tissues In Human Primary Myelofibrosis With JAK2 V617F Are Developed Clonally From Malignant Hematopoietic Stem Cells

Takuji Yamauchi, MD, PhD, Takahiro Shima, MD, Katsuto Takenaka, MD, PhD, Toshihiro Miyamoto, MD, Koichi Akashi, MD, PhD

Blood (2013) 122 (21): 4106.

https://doi.org/10.1182/blood.V122.21.4106.4106

Published: 2013

Journal Articles

BALB/c- Specific L29V Polymorphism In SIRPA Determines The Efficient Engraftment Of Human Hematopoiesis In Xenogeneic Model

Chika Iwamoto, Katsuto Takenaka, MD, PhD, Shingo Urata, MD, Takahiro Shima, MD, Takuji Yamauchi, MD, PhD, Takuro Kuriyama, MD, PhD, Shinya Daitoku, MD, Yasuyuki Saito, MD, PhD, Katsuhiko Itoh, MD, PhD, Junji Kishimoto, PhD, Daisuke Kohda, PhD, Takashi Matozaki, MD, PhD, Koichi Akashi, MD, PhD

Blood (2013) 122 (21): 337.

https://doi.org/10.1182/blood.V122.21.337.337

Published: 2013

Journal Articles

Establishment of a New Immunodeficient Mouse Line Harboring NOD-Type Sirpa with Highly-Efficient Human Hematopoietic Cell Engraftment.

Takuji Yamauchi, M.D., Katsuto Takenaka, MD, PhD, Shingo Urata, M.D., Takahiro Shima, MD, Yoshikane Kikushige, MD, PhD, Takahito Tokuyama, MD, Chika Iwamoto, Toshihiro Miyamoto, MD, PhD, Koichi Akashi, MD, PhD.

Blood (2012) 120 (21): 2301.

https://doi.org/10.1182/blood.V120.21.2301.2301

Published: 2012

Journal Articles

The Deposition of H3.3 Mediated by Transcription Factors Determines Hematopoietic Cell Fate

Jun Odawara, MD, Kohta Miyawaki, MD, Kentaro Kohno, MD, Takahiro Shima, MD, Kazumitsu Maehara, Akihito Harada, PhD, Masayasu Hayashi, MD, Masao Nagasaki, PhD, Yasuyuki Ohkawa, PhD, Koichi Akashi, MD, PhD.

Blood (2012) 120 (21): 1193.

https://doi.org/10.1182/blood.V120.21.1193.1193

Published: 2012

Journal Articles

Prospective Isolation of the Earliest Common Myeloid Progenitor in Adult Hematopoiesis

Kohta Miyawaki, MD, Yojiro Arinobu, MD, PhD, Kentaro Kohno, MD, Hirofumi Tsuzuki, Tadafumi Iino, MD, Takahiro Shima, MD, Hiromi Iwasaki, MD, PhD, Koichi Akashi, MD, PhD.

Blood (2012) 120 (21): 768.

https://doi.org/10.1182/blood.V120.21.768.768

Published: 2012

Journal Articles

The First Demonstration of Sequential Acquisition of Class I and Class II Gene Mutations in Formation of Human Acute Myeloid Leukemia Stem Cells

Takahiro Shima, MD, Yoshikane Kikushige, MD, PhD, Toshihiro Miyamoto, MD, PhD, Koichi Akashi, MD, PhD.

Blood (2012) 120 (21): 859.

https://doi.org/10.1182/blood.V120.21.859.859

Published: 2012

NARROW

Platelet Decrease and Efficacy of Platelet-Rich Plasma Return for Peripheral Blood Stem Cell Apheresis

RUNX1 Deficiency Cooperates with SRSF2 Mutation to Further Disrupt RNA Splicing and Exacerbate Myelodysplastic Syndromes in Mouse Models

CPSF1-Mediated Acute Myeloid Leukemia Fusion 3'UTR Alternation Is a Potential Therapeutic Target

FIP1L1 Regulates Alternative Polyadenylation of Leukemia-Associated Genes in Acute Myeloid Leukemia

Hippo Kinase Inactivation Contributes to Del(20q) Malignancies and Cooperates with JAK2-V617F to Promote Myelofibrosis in Mice

RUNX1 Deficiency and SRSF2 Mutation Cooperate to Promote Myelodysplastic Syndrome Development

Characterization of the Post-Transcriptional Regulation of AML1-ETO Expression in t(8;21) Leukemia Cells

CPSF1 Regulates AML1-ETO Fusion Gene Polyadenylation and Stability in t(8;21) Acute Myelogenous Leukemia

Usp18 Is Required for Normal Stem Cell Maintenance

Prior Use of Mogamulizumab to Allogenic Hematopoietic Stem Cell Transplantation Induces Severe Acute Graft-Versus-Host Disease

TIM-3 and Its Ligand, Galectin-9 Constitute a Pan-Myeloid Autocrine Loop to Develop and Maintain Malignant Stem Cells in Most Human Myeloid Leukemia

TIM-3, a Leukemia Stem Cell Marker, Plays a Role In Leukemic Transformation Through Autocrine Stimulatory Signaling By Its Ligand, Galectin-9

Visualization Of Normal and Malignant Epigenetic Regulation In Hematopoiesis Utilizing Newly-Developed Histone Variant H3.3 Chipseq Analysis

The Expansion Of CML Clones Initiates At The CMP Stage, and Is Associated With The Down-Regulation Of IRF8 and GFI1

Fibrotic Tissues In Human Primary Myelofibrosis With JAK2 V617F Are Developed Clonally From Malignant Hematopoietic Stem Cells

BALB/c- Specific L29V Polymorphism In SIRPA Determines The Efficient Engraftment Of Human Hematopoiesis In Xenogeneic Model

Establishment of a New Immunodeficient Mouse Line Harboring NOD-Type Sirpa with Highly-Efficient Human Hematopoietic Cell Engraftment.

The Deposition of H3.3 Mediated by Transcription Factors Determines Hematopoietic Cell Fate

Prospective Isolation of the Earliest Common Myeloid Progenitor in Adult Hematopoiesis

The First Demonstration of Sequential Acquisition of Class I and Class II Gene Mutations in Formation of Human Acute Myeloid Leukemia Stem Cells

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American Society of Hematology

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ASH Publications

American Society of Hematology

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