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Swaroopa Guda, PhD
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Journal Articles

Preclinical Evaluation of a Novel Lentiviral Vector Driving Lineage-Specific BCL11A Knockdown, β-Globin Induction and Simultaneous Repression of β-Globin for the Potential Treatment of Sickle Cell Disease

Olivier Negre, PhD, Christian Brendel, PhD, Geoffrey B. Parsons, Min Luo, PhD, Myriam A Armant, PhD, Swaroopa Guda, PhD, Lauryn Christiansen, Gretchen Lewis, BMBS, Gabor Veres, PhD, Melissa Bonner, PhD, David A. Williams, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3557.
https://doi.org/10.1182/blood.V130.Suppl_1.3557.3557
Published: 2017
Journal Articles

Optimization of Bcl11a Knockdown By miRNA Scaffold Embedded Shrnas Leading to Enhanced Induction of Fetal Hemoglobin in Erythroid Cells for the Treatment of Beta-Hemoglobinopathies

Christian Brendel, PhD, Swaroopa Guda, PhD, Raffaele Renella, MD PhD, Peng Du, PhD, Daniel E. Bauer, MD, PhD, Matthew C. Canver, BS, Sophia C. Kamran, MD, James Thornton, PhD, Helen de Boer, BAS, Michael D. Milsom, PhD, Stuart H. Orkin, MD, Richard Gregory, PhD, David A. Williams, MD
Journal: Blood
Blood (2014) 124 (21): 2150.
https://doi.org/10.1182/blood.V124.21.2150.2150
Published: 2014
Journal Articles

Hematopoietic SIN Lentiviral Micro RNA-Mediated Silencing of BCL11A: Pre-Clinical Evidence for a Sickle Cell Disease Gene-Therapy Trial

Raffaele Renella, MD, PhD, Aleksej Perlov, Chad E Harris, Daniel E. Bauer, MD, PhD, Jian Xu, PhD, Swaroopa Guda, PhD, Michael D. Milsom, PhD, Stuart H. Orkin, MD, David A. Williams, MD
Journal: Blood
Blood (2012) 120 (21): 753.
https://doi.org/10.1182/blood.V120.21.753.753
Published: 2012