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Steve L. Abrams, BS
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Journal Articles

The AKT Inhibitor, A443654, Induces Cell Cycle Arrest, Apoptosis and Synergizes with Chemotherapeutic Drugs in Multi-Drug Resistant T-Cell Acute Lymphoblastic Leukemia - A Novel Agent for Therapy of Drug Resistant ALL.

James A. McCubrey, PhD, William L. Blalock, PhD, Pier Luigi Tazzari, MD, Alessandra Cappellini, PhD, Ilaria Iacobucci, PhD, Francesca Chiarini, BS, Steve L. Abrams, BS, Emanuela Ottaviani, PhD, Giovanni Martinelli, MD, Agostino Tafuri, MD, Lucio Cocco, MD PhD, Alberto M. Martelli, MD PhD, Federica Fala, MD
Journal: Blood
Blood (2007) 110 (11): 3344.
https://doi.org/10.1182/blood.V110.11.3344.3344
Published: 2007
Journal Articles

The Novel Akt Inhibitor Perifosine Induces Apoptosis, Cell Cycle Arrest and Synergizes with Chemotherapeutic Drugs in Acute Myelogenous Leukemia Cells by a JNK Dependent Mechanism - A Novel Therapeutic Approach for Leukemia Displaying Elevated Akt Signaling.

Alberto M. Martelli, MD, PhD, Veronica Papa, BS, Pier Luigi Tazzari, MD, Francesca Chiarini, BS, Alessandra Cappellini, PhD, Francesca Ricci, BS, Anna Maria Billi, PhD, Camilla Evangelisti, PhD, Steve L. Abrams, BS, Emanuela Ottaviani, PhD, Giovanni Martinelli, MD, James A. McCubrey, PhD
Journal: Blood
Blood (2007) 110 (11): 3355.
https://doi.org/10.1182/blood.V110.11.3355.3355
Published: 2007
Journal Articles

Roles of Raf/MEK/ERK and PI3K/Akt/mTOR Pathways in Prevention of Apoptosis and Induction of Drug Resistance in Myeloid Hematopoietic Cells.

Steve L. Abrams, BS, Camilla Evangelisti, PhD, Francesca Chiarini, BS, Negin Misaghian, BS, Jorg Basecke, MD, Michele Millela, MD, Agostino Tafuri, MD, Massimo Libra, MD, Franca Stivala, MD, Marina Konopleva, MD, Michael Andreeff, MD, Linda S. Steelman, MS, Jacob Troppmair, PhD, Alberto M. Martelli, MD, James A. McCubrey, PhD
Journal: Blood
Blood (2007) 110 (11): 641.
https://doi.org/10.1182/blood.V110.11.641.641
Published: 2007