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Journal Articles

IGHV Gene Replacement: A Potential Mechanism for Establishing Stereotypy in Certain Cases of Chronic Lymphocytic Leukemia

Sophia Yancopoulos, PhD, Wentian Li, PhD, Xiao J. Yan, MD PhD, Andreas Agathangelidis, PhD, Anastasia Hadzidimitriou, PhD, Frederic Davi, MD PhD, Richard Rosenquist, MD PhD, Paolo Ghia, MD PhD, Kostas Stamatopoulos, MD PhD, Nicholas Chiorazzi, MD

Blood (2018) 132 (Supplement 1): 1841.

https://doi.org/10.1182/blood-2018-99-119803

Published: 2018

Journal Articles

B Cells of the Proliferative Fraction of CLL Clones Exhibit Activated B-Cell and Myeloid-Cell Signatures Suggesting Enhanced Antigen-Presentation, Integrin Responsiveness, and IL-4 Receptiveness: Additional Targets for CLL Therapy

Xiao-Jie Yan, MD PhD, Florencia Palacios, PhD, Wentian Li, PhD, Sophia Yancopoulos, PhD, Carlo Calissano, MD, Jacqueline C. Barrientos, MD, Steven L. Allen, MD, Jonathan E. Kolitz, MD, Kanti Rai, MD, Nicholas Chiorazzi, MD

Blood (2016) 128 (22): 302.

https://doi.org/10.1182/blood.V128.22.302.302

Published: 2016

Journal Articles

In CLL, Myeloid-Derived Suppressor Cells and Their Monocytic and Granulocytic Varieties Differ in T-Cell Subset Association and Polarization Induction

Gerardo Ferrer, PhD, Brendan Franca, Pui Yan Chiu, MSc, Stefano Vergani, MS, Andrea Nicola Mazzarello, PhD, Florencia Palacios, PhD, Davide Bagnara, PhD, Shih-Shih Chen, PhD, Sophia Yancopoulos, PhD, Yun Liu, MS, Aliki Xochelli, MD PhD, Xiao-Jie Yan, MD PhD, Jacqueline C. Barrientos, MD, Jonathan E. Kolitz, MD, Steven L. Allen, MD, Kostas Stamatopoulos, MD PhD, Kanti R. Rai, MD, Barbara Sherry, PhD, Nicholas Chiorazzi, MD

Blood (2016) 128 (22): 4350.

https://doi.org/10.1182/blood.V128.22.4350.4350

Published: 2016

Journal Articles

CLL Stereotyped IGHV-D-J Rearrangements Can Be Detected Throughout Normal B-Cell Developmental Stages in Aged People When Using Ultra-Deep, Next Generation Sequencing Techniques

Stefano Vergani, MS, Davide Bagnara, PhD, Andrea Nicola Mazzarello, PhD, Gerardo Ferrer, PhD, Sophia Yancopoulos, PhD, Kostas Stamatopoulos, MD PhD, Nicholas Chiorazzi, MD

Blood (2016) 128 (22): 2028.

https://doi.org/10.1182/blood.V128.22.2028.2028

Published: 2016

Journal Articles

Comparative Density Analyses of B Cell Receptor-Complex Components (Membrane IgM, Membrane IgD, and Stimulatory/Inhibitory Co-Receptors) on Intraclonal Subpopulations of CLL B Cells, before and during Ibrutinib Therapy

Andrea Nicola Mazzarello, PhD, Stefano Vergani, MS, Gerardo Ferrer, PhD, Yun Liu, MS, Shih-Shih Chen, PhD, Sophia Yancopoulos, PhD, Xiao-Jie Yan, MD PhD, Jacqueline C. Barrientos, MD, Kanti R. Rai, MD, Nicholas Chiorazzi, MD

Blood (2016) 128 (22): 4356.

https://doi.org/10.1182/blood.V128.22.4356.4356

Published: 2016

Journal Articles

A Systematic Search Into The Role Of IGHV Gene Replacement In Shaping The Immunoglobulin Repertoire Of Chronic Lymphocytic Leukemia

Sophia Yancopoulos, PhD, Xiao-Jie Yan, MD PhD, Andreas Agathangelidis, Wentian Li, Ph.D., Chrysoula Belessi, Paolo Ghia, MD, PhD, Richard Rosenquist, MD, PhD, Frederic Davi, MD, PhD, David Graham Oscier, MD, Sarka Pospisilova, Panagiotis Panagiotidis, MD, Lin Huang, PhD, Zhixin Zhang, PhD, Steven L. Allen, MD, Jaqueline C. Barrientos, MD, Jonathan E. Kolitz, MD, Kanti R. Rai, MD, Kostas Stamatopoulos, MD, Nicholas Chiorazzi, MD

Blood (2013) 122 (21): 4129.

https://doi.org/10.1182/blood.V122.21.4129.4129

Published: 2013

Journal Articles

Gene Expression Profiles Document That Recently- and Previously-Divided CLL Fractions Represent a Continuum but Suggest Differing Modes of Activation for These Fractions in U-CLL and M-CLL

Xiao J. Yan, MD, PhD, Wentian Li, Ph.D., Sophia Yancopoulos, PhD, Igor Dozmorov, PhD, Carlo Calissano, MD, Sonia Marsilio, PhD, Rajendra N Damle, PhD, Steven L. Allen, MD, Jonathan E. Kolitz, MD, Jacqueline C. Barrientos, MD, Kanti R. Rai, M.D., Nicholas Chiorazzi, MD

Blood (2012) 120 (21): 317.

https://doi.org/10.1182/blood.V120.21.317.317

Published: 2012

Journal Articles

Gene Set Enrichment Analysis of Ki-67 high CLL Clones Suggests Complex Interactions of B-Cell Receptor Signaling and Normal Cell Interactions in the Disease

Xiao J. Yan, MD, PhD, Daniel Kalenscher, Erin Boyle, Sophia Yancopoulos, PhD, Rajendra N Damle, PhD, Aarti Damle, Houman Khalili, Annette Lee, PhD, Wentian Li, Ph.D., Igor Dozmorov, MD, PhD, Matthew Kaufman, M.D., Peter Gregersen, MD, Steven L. Allen, M.D., Jonathan E. Kolitz, MD, Kanti R. Rai, MD, Nicholas Chiorazzi, M.D.

Blood (2011) 118 (21): 2833.

https://doi.org/10.1182/blood.V118.21.2833.2833

Published: 2011

Journal Articles

Combining Expression of Hypervariably Expressed Genes with IGHV Mutation Status Is a More Robust Prognostic Indicator Than Mutation Status Alone in Chronic Lymphocytic Leukemia

Blood (2011) 118 (21): 1774.

https://doi.org/10.1182/blood.V118.21.1774.1774

Published: 2011

NARROW

IGHV Gene Replacement: A Potential Mechanism for Establishing Stereotypy in Certain Cases of Chronic Lymphocytic Leukemia

B Cells of the Proliferative Fraction of CLL Clones Exhibit Activated B-Cell and Myeloid-Cell Signatures Suggesting Enhanced Antigen-Presentation, Integrin Responsiveness, and IL-4 Receptiveness: Additional Targets for CLL Therapy

In CLL, Myeloid-Derived Suppressor Cells and Their Monocytic and Granulocytic Varieties Differ in T-Cell Subset Association and Polarization Induction

CLL Stereotyped IGHV-D-J Rearrangements Can Be Detected Throughout Normal B-Cell Developmental Stages in Aged People When Using Ultra-Deep, Next Generation Sequencing Techniques

Comparative Density Analyses of B Cell Receptor-Complex Components (Membrane IgM, Membrane IgD, and Stimulatory/Inhibitory Co-Receptors) on Intraclonal Subpopulations of CLL B Cells, before and during Ibrutinib Therapy

A Systematic Search Into The Role Of IGHV Gene Replacement In Shaping The Immunoglobulin Repertoire Of Chronic Lymphocytic Leukemia

Gene Expression Profiles Document That Recently- and Previously-Divided CLL Fractions Represent a Continuum but Suggest Differing Modes of Activation for These Fractions in U-CLL and M-CLL

Gene Set Enrichment Analysis of Ki-67 high CLL Clones Suggests Complex Interactions of B-Cell Receptor Signaling and Normal Cell Interactions in the Disease

Combining Expression of Hypervariably Expressed Genes with IGHV Mutation Status Is a More Robust Prognostic Indicator Than Mutation Status Alone in Chronic Lymphocytic Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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