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Journal Articles

Distinct Genetic Pathways Define Leukemia Predisposition Versus Adaptive Clonal Hematopoiesis in Shwachman-Diamond Syndrome

Alyssa L. Kennedy, MDPhD, Kasiani C. Myers, MD, James Bowman, PhD, Christopher J. Gibson, MD, Gwen M. Muscato, Robert Klein, Kaitlyn Ballotti, Nicholas Camarda, Elissa M. Furutani, MD, Chad E. Harris, MS, Shanshan Liu, PhD, Ashley Galvin, Maggie Malsch, MSN, RN, David C. Dale, MD, John M Gansner, MD PhD, Taizo A. Nakano, MD, Alison A. Bertuch, MD, Adrianna Vlachos, MD, Jeff H. Lipton, MD PhD, Paul Castillo, MD, James Connelly, John Edwards, MD, Nobuko Hijiya, MD, Richard Ho, MD, Inga Hofmann, MD, James N Huang, MD, Sioban B. Keel, MD, Adam J. Lamble, MD, Bonnie W Lau, MD PhD, Kelly J. Walkovich, MD, Maxim Norkin, MD, Wendy Stock, MD, Steffen Boettcher, Christian Brendel, PhD, Elliot Stieglitz, MD, Mark D. Fleming, MD DPhil, Stella M. Davies, PhD MBBS, MRCP, Edie A. Weller, Chris Bahl, PhD, Scott L. Carter, PhD, Akiko Shimamura, MD PhD, R. Coleman Lindsley, MD PhD

Blood (2020) 136 (Supplement 1): 35–36.

https://doi.org/10.1182/blood-2020-137125

Published: 2020

Journal Articles

Phase 1 Trial of Cladribine, High-Dose Cytarabine, G-CSF, and Dose-Escalated Mitoxantrone (CLAG-M) Plus Gemtuzumab Ozogamicin in Adults with Newly-Diagnosed Acute Myeloid Leukemia (AML) or Other High-Grade Myeloid Neoplasm

Colin D. Godwin, MDMPhil, Megan Othus, PhD, Mary-Elizabeth M. Percival, MD, Bart L. Scott, MD, Pamela S. Becker, MD PhD, Kelda M. Gardner, PA-C, Sioban B. Keel, MD, Tejaswini M. Dhawale, MD, Vivian G. Oehler, MD, Janis L. Abkowitz, MD, Anna B. Halpern, MD, Paul C. Hendrie, MD PhD, Kaysey F. Orlowski, Alice Woo, Elihu H. Estey, MD, Roland B. Walter, MD PhD MS

Blood (2019) 134 (Supplement_1): 3892.

https://doi.org/10.1182/blood-2019-126009

Published: 2019

Journal Articles

Comparison of Outcomes after Early Hospital Discharge (EHD) Following Intensive Induction Vs. Post-Remission Chemotherapy for Adults with Acute Myeloid Leukemia (AML) and Other High-Grade Myeloid Neoplasms

Anna B. Halpern, MD, Nicholas P Howard, Megan Othus, PhD, Paul C. Hendrie, MD PhD, Nikita Vashi Baclig, MD MPH, Sarah A Buckley, MD, Mary-Elizabeth M. Percival, MD, Pamela S. Becker, MD PhD, Bart L. Scott, MD, Vivian G. Oehler, MD, Terry B. Gernsheimer, MD, Sioban B. Keel, MD, Johnnie Orozco, MD, Ryan D. Cassaday, MD, Andrei R Shustov, MD, Garrett Hartley, Verna L Welch, PhD MPH, Elihu H. Estey, MD, Roland B. Walter, MD PhD MS

Blood (2019) 134 (Supplement_1): 1317.

https://doi.org/10.1182/blood-2019-124586

Published: 2019

Journal Articles

Germline and Somatic Genetic Characterization of Shwachman-Diamond Syndrome

Kasiani C. Myers, MD, Adam S. Nelson, MBBS, Brian Sheehan, Maggie Malsch, Gwendolyn Towers, Audrey Anna Bolyard, RN, BS, Joan Moore, Sara Loveless, Leann Mount, Stella M Davies, MBBS, PhD, Siobán B. Keel, MD, Rabi Hanna, MD, Mark D. Fleming, MD DPhil, David C. Dale, MD, Akiko Shimamura, MD PhD

Blood (2016) 128 (22): 2681.

https://doi.org/10.1182/blood.V128.22.2681.2681

Published: 2016

Journal Articles

Detection of Mutations in Inherited Bone Marrow Failure and Myelodysplastic Syndrome Genes Using Genomic Capture and Massively Parallel Sequencing in Clinical Diagnostics

Siobán B. Keel, MD, Tom Walsh, PhD, Colin Pritchard, MD, Akiko Shimamura, MD PhD, Mary-Claire King, PhD, David Wu, MD PhD

Blood (2016) 128 (22): 1507.

https://doi.org/10.1182/blood.V128.22.1507.1507

Published: 2016

Journal Articles

The Interplay of GATA1 with Heme Regulates an Erythroid Cell's Differentiation

Raymond T Doty, PhD, Xiaowei Yan, PhD, Christopher Lausted, MS, Zhantao Yang, MD, Li Liu, PhD, Neda Jabbari, PhD, Siobán B. Keel, MD, Qiang Tian, MD PhD, Janis L. Abkowitz, MD

Blood (2016) 128 (22): 541.

https://doi.org/10.1182/blood.V128.22.541.541

Published: 2016

Journal Articles

Pathophysiology of Macrocytic Anemia in Diamond Blackfan Anemia and Del(5q) Myelodysplastic Syndrome

Zhantao Yang, MD, Sioban B. Keel, MD, Brent L. Wood, MDPhD, Bart L. Scott, MD MS, Janis L. Abkowitz, MD

Blood (2015) 126 (23): 670.

https://doi.org/10.1182/blood.V126.23.670.670

Published: 2015

Journal Articles

Phase 2 Study Of Early Discharge and Outpatient Management Of Adult Patients Following Intensive Induction Chemotherapy For MDS and Non-APL AML

Jennifer E. Vaughn, MD, MSPH, Morgan A. Powell, BS, Kelda M. Gardner, PA-C, Megan Othus, PhD, Rajeev Rajendra, MD, PhD, Donnelle Rizutto, RN, Pamela S. Becker, MD, PhD, Paul C. Hendrie, MD, PhD, Andrei R. Shustov, MD, Siobán B. Keel, MD, Vivian G. Oehler, MD, Terry B. Gernsheimer, MD, Janis L. Abkowitz, MD, Elihu H. Estey, MD, Roland B. Walter, MD, PhD

Blood (2013) 122 (21): 2932.

https://doi.org/10.1182/blood.V122.21.2932.2932

Published: 2013

Journal Articles

Comprehensive Genomic Evaluation For Inherited Bone Marrow Failure/Myelodysplastic Syndromes

Michael Zhang, Siobán B. Keel, MD, Tom Walsh, PhD, Ming Lee, Pritchard Colin, MD, PhD, Michael Jeng, MD, Amanda Watts, Janis L. Abkowitz, MD, Mary-Claire King, PhD, Akiko Shimamura, MD, PhD

Blood (2013) 122 (21): 592.

https://doi.org/10.1182/blood.V122.21.592.592

Published: 2013

Journal Articles

FLVCR1a But Not FLVCR1b Is Required For Effective Erythropoiesis In Adult Mice

Raymond T Doty, PhD, Marilyn Sanchez-Bonilla, Siobán B. Keel, MD, Janis L. Abkowitz, MD

Blood (2013) 122 (21): 308.

https://doi.org/10.1182/blood.V122.21.308.308

Published: 2013

Journal Articles

Murine Terminal Erythroid Differentiation and Early B Development Require the Sodium-Dependent Phosphate Import Protein, PiT1.

Li Liu, Marilyn Sanchez-Bonilla, Matthew Crouthamel, Cecilia Giachelli, Sioban B Keel, MD

Blood (2012) 120 (21): 2307.

https://doi.org/10.1182/blood.V120.21.2307.2307

Published: 2012

Journal Articles

Heme Excess Impairs the Maturation of Proerythroblasts From Patients with Diamond Blackfan Anemia (DBA) and 5q- Myelodysplastic Syndrome (MDS)

Zhantao Yang, MD, Sioban B Keel, MD, Akiko Shimamura, MD, PhD, Aaron T. Gerds, MD, Bart L. Scott, MD, MS, Janis L. Abkowitz, MD

Blood (2012) 120 (21): 514.

https://doi.org/10.1182/blood.V120.21.514.514

Published: 2012

Journal Articles

Why Do Erythroid Cells Need to Export Heme?

Janis L. Abkowitz, MD, Sioban B Keel, MD, Mary Philip, MD PhD, John C Byon, MD PhD, Raymond T Doty, PhD

Blood (2011) 118 (21): SCI-24.

https://doi.org/10.1182/blood.V118.21.SCI-24.SCI-24

Published: 2011

Journal Articles

Mice Lacking the Sodium-Dependent Phosphate Import Protein, Pit-1, Have a Severe Defect in Terminal Erythroid Differentiation

Li Liu, Marilyn Sanchez-Bonilla, Yan Wang, Mathew Crouthamel, Cecilia Giachelli, Sioban B Keel, MD

Blood (2011) 118 (21): 681.

https://doi.org/10.1182/blood.V118.21.681.681

Published: 2011

Journal Articles

Defining the Pathophysiology of Pure Red Cell Aplasia Due to Feline Leukemic Virus Subgroup C Receptor (FLVCR) Dysfunction: Does Heme Toxicity Account for the Erythroid Marrow Failure?

Sioban B Keel, MD, Marilyn Sanchez-Bonilla, Li Liu, Yan Wang, Janis L. Abkowitz, MD

Blood (2011) 118 (21): 175.

https://doi.org/10.1182/blood.V118.21.175.175

Published: 2011

Journal Articles

Characterization of the Hematologic Phenotype of rpS6 Heterozygous Null Mice as a Model of the Erythroid Failure In Diamond-Blackfan Anemia

Sioban B. Keel, MD, Janis L. Abkowitz, MD

Blood (2010) 116 (21): 2033.

https://doi.org/10.1182/blood.V116.21.2033.2033

Published: 2010

Journal Articles

A Heme Export Protein Is Required for Red Cell Differentiation and Iron Homeostasis.

Sioban B. Keel, MD, Raymond T. Doty, PhD, Sue Knoblaugh, DVM, Ivana De Domenico, PhD, Jerry Kaplan, PhD, Janis L. Abkowitz, MD

Blood (2007) 110 (11): 2658.

https://doi.org/10.1182/blood.V110.11.2658.2658

Published: 2007

Journal Articles

A Heme Export Protein Is Required for Red Cell Differentiation and May Facilitate Iron Homeostasis.

Sioban B. Keel, MD, Raymond T. Doty, Ph.D., Zhantao Yang, M.D., James Palis, M.D., Janis L. Abkowitz, M.D.

Blood (2006) 108 (11): 1540.

https://doi.org/10.1182/blood.V108.11.1540.1540

Published: 2006

NARROW

Distinct Genetic Pathways Define Leukemia Predisposition Versus Adaptive Clonal Hematopoiesis in Shwachman-Diamond Syndrome

Phase 1 Trial of Cladribine, High-Dose Cytarabine, G-CSF, and Dose-Escalated Mitoxantrone (CLAG-M) Plus Gemtuzumab Ozogamicin in Adults with Newly-Diagnosed Acute Myeloid Leukemia (AML) or Other High-Grade Myeloid Neoplasm

Comparison of Outcomes after Early Hospital Discharge (EHD) Following Intensive Induction Vs. Post-Remission Chemotherapy for Adults with Acute Myeloid Leukemia (AML) and Other High-Grade Myeloid Neoplasms

Germline and Somatic Genetic Characterization of Shwachman-Diamond Syndrome

Detection of Mutations in Inherited Bone Marrow Failure and Myelodysplastic Syndrome Genes Using Genomic Capture and Massively Parallel Sequencing in Clinical Diagnostics

The Interplay of GATA1 with Heme Regulates an Erythroid Cell's Differentiation

Pathophysiology of Macrocytic Anemia in Diamond Blackfan Anemia and Del(5q) Myelodysplastic Syndrome

Phase 2 Study Of Early Discharge and Outpatient Management Of Adult Patients Following Intensive Induction Chemotherapy For MDS and Non-APL AML

Comprehensive Genomic Evaluation For Inherited Bone Marrow Failure/Myelodysplastic Syndromes

FLVCR1a But Not FLVCR1b Is Required For Effective Erythropoiesis In Adult Mice

Murine Terminal Erythroid Differentiation and Early B Development Require the Sodium-Dependent Phosphate Import Protein, PiT1.

Heme Excess Impairs the Maturation of Proerythroblasts From Patients with Diamond Blackfan Anemia (DBA) and 5q- Myelodysplastic Syndrome (MDS)

Why Do Erythroid Cells Need to Export Heme?

Mice Lacking the Sodium-Dependent Phosphate Import Protein, Pit-1, Have a Severe Defect in Terminal Erythroid Differentiation

Defining the Pathophysiology of Pure Red Cell Aplasia Due to Feline Leukemic Virus Subgroup C Receptor (FLVCR) Dysfunction: Does Heme Toxicity Account for the Erythroid Marrow Failure?

Characterization of the Hematologic Phenotype of rpS6 Heterozygous Null Mice as a Model of the Erythroid Failure In Diamond-Blackfan Anemia

A Heme Export Protein Is Required for Red Cell Differentiation and Iron Homeostasis.

A Heme Export Protein Is Required for Red Cell Differentiation and May Facilitate Iron Homeostasis.

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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