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Silvia Laura Locatelli, PhD
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Journal Articles

RNA Sequencing Reveals Mechanisms Underlying Modulation of Hodgkin Lymphoma Cells and Tumor Microenvironment By the PI3K δ/γ Inhibitor, RP6530

Silvia Laura Locatelli, PhD, Francesca Maria Consonni, PhD, Giuseppa Careddu, Simone Serio, Srikant Viswanadha, PhD, Swaroop Kumar VS Vakkalanka, PhD, Lucia Morello, MD, Massimo Magagnoli, MD, Luca Castagna, MD, Armando Santoro, MD, Antonio Sica, PhD, Carmelo Carlo-Stella, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2476.
https://doi.org/10.1182/blood.V130.Suppl_1.2476.2476
Published: 2017
Journal Articles

The Novel Calcium Release-Activated Calcium (CRAC) Channel Inhibitor RP4010 Exerts Potent Antitumor Effects in NOD/SCID/IL2Rg -/- Mice with Diffuse Large B Cell Lymphoma (DLBCL) Cell Line Xenografts

Silvia Laura Locatelli, PhD, Giuseppa Careddu, Massimo Magagnoli, MD, Martina di Trani, Lucia Morello, MD, Srikant Viswanadha, PhD, Swaroop Kumar VS Vakkalanka, PhD, Luca Castagna, MD, Armando Santoro, MD, Carmelo Carlo-Stella, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4101.
https://doi.org/10.1182/blood.V130.Suppl_1.4101.4101
Published: 2017
Journal Articles

Treatment of Hodgkin Lymphoma Xenografts with the Novel PI3K δ/γ Inhibitor RP6530 Suppresses M2 Macrophage Polarization and Results in Potent Antitumor and Antiangiogenic Effects

Silvia Laura Locatelli, PhD, Francesca Maria Consonni, Giuseppa Careddu, Simone Serio, Srikant Viswanadha, PhD, Swaroop Vakkalanka, PhD, Luca Castagna, MD, Armando Santoro, MD, Carmelo Carlo-Stella, MD
Journal: Blood
Blood (2016) 128 (22): 45.
https://doi.org/10.1182/blood.V128.22.45.45
Published: 2016
Journal Articles

Clinical Activity and Safety of RP6530, a Dual PI3Kδ/γ Inhibitor, in Patients with Advanced Hematologic Malignancies: Final Analysis of a Phase 1 Multicenter Study

Carmelo Carlo-Stella, MD, Richard Delarue, MD, Prajak J Barde, MD, Lydia Scarfo, Uday Kumar, Srikant Viswanadha, PhD, Silvia Laura Locatelli, PhD, Sara Gandolfi, MD, Valeria Pittari, MD, Lucia Morello, Massimo Magagnoli, Armando Santoro, Andrés J.M. Ferreri, MD
Journal: Blood
Blood (2016) 128 (22): 3011.
https://doi.org/10.1182/blood.V128.22.3011.3011
Published: 2016
Journal Articles

Synergistic Induction of Cell Death in Hodgkin Lymphoma Cells By the Novel PI3K Inhibitor RP6530 Combined with Brentuximab Vedotin (SGN-35) through Inhibition of Tumor Angiogenesis

Silvia Laura Locatelli, PhD, Giuseppa Careddu, Armando Chierchia, Srikant Viswanadha, PhD, Swaroop Vakkalanka, PhD, Luca Castagna, Armando Santoro, MD, Carmelo Carlo-Stella, MD
Journal: Blood
Blood (2015) 126 (23): 1561.
https://doi.org/10.1182/blood.V126.23.1561.1561
Published: 2015
Journal Articles

A Dose Escalation Study of RP6530, a Novel Dual PI3K Delta/Gamma Inhibitor, in Patients with Relapsed/Refractory Hematologic Malignancies

Carmelo Carlo-Stella, MD, Richard Delarue, MD, Prajak J Barde, MD, Lydia Scarfo, Thamila Saheb, Uday Kumar, Srikant Viswanadha, PhD, Sara Gandolfi, MD, Valeria Pittari, MD, Armando Santoro, MD, Silvia Laura Locatelli, PhD, Swaroop Vakkalanka, PhD, Paolo Ghia, MD PhD, Andres J.M. Ferreri
Journal: Blood
Blood (2015) 126 (23): 1495.
https://doi.org/10.1182/blood.V126.23.1495.1495
Published: 2015