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Shannon Renee Sweeney, MS
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Journal Articles

Mitochondrial Complex I Inhibitor Iacs-010759 Reverses the NOTCH1-Driven Metabolic Reprogramming in T-ALL Via Blockade of Oxidative Phosphorylation: Synergy with Chemotherapy and Glutaminase Inhibition

Natalia Baran, PhDMD, Alessia Lodi, PhD, Shannon Renee Sweeney, MS, Pandey Renu, PhD, Vinitha Mary Kuruvilla, Antonio Cavazos, MSc, Daniel Herranz, PharmD, Anna Skwarska, PhD, Marc Warmoes, PhD, R. Eric Davis, MD, Karine Harutyunyan, PhD, Ningping Feng, PhD, Jason P Gay, MS, Sergej Naumovich Konoplev, MD PhD, Marcin Kaminski, PhD, Jeffrey J Kovacs, PhD, Di Du, PhD, Elias J. Jabbour, MD, Adolfo A. Ferrando, MD PhD, Maria E Di Francesco, PhD, Philip L Lorenzi, PhD, Joseph R Marszalek, PhD, Stefano Tiziani, PhD, Marina Y. Konopleva, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4020.
https://doi.org/10.1182/blood-2018-99-117310
Published: 2018
Journal Articles

Inhibition of Oxphos with Iacs-010759 Depletes AML Leukemia Initiating Cells (LIC) in Vitro and Improves Survival in Pre-Clinical AML Models

Natalia Baran, PhD MD, Lina Han, PhD, Shannon Renee Sweeney, MS, Alessia Lodi, PhD, Shelley Herbrich, MS, Antonio Cavazos, MSc, Helen Ma, MS, Jason P Gay, MS, Ningping Feng, PhD, Hsiang-Chun Chen, PhD, Marcin Kaminski, PhD, Kenneth Dunner, Jr., AS, BS, Guilin Tang, MD, Gheath Alatrash, DO, PhD, Jennifer Molina, PhD, Monica L. Guzman, PhD, Jing Ning, PhD, Stefano Tiziani, PhD, Joseph R Marszalek, PhD, Marina Konopleva, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1350.
https://doi.org/10.1182/blood.V130.Suppl_1.1350.1350
Published: 2017