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    Sean O'Brien, Ph.D.
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    Journal Articles

    CX-5461, a Novel RNA Polymerase I Inhibitor, Is Active Against Wild-Type and Mutant p53 Myeloma Models

    Hans C. Lee, MD, Hua Wang, Ph.D., Bing-Zong Li, M.D., Ph.D., Zhiqiang Wang, Ph.D., Richard Julian Jones, Ph.D., Dongmin Gu, M.D., Ph.D., Sean O'Brien, Ph.D., Richard E. Davis, M.D., Robert Z. Orlowski, M.D., Ph.D.
    Journal: Blood
    Blood (2013) 122 (21): 4438.
    https://doi.org/10.1182/blood.V122.21.4438.4438
    Published: 2013
    Journal Articles

    Inhibition Of RNA Polymerase I Transcription By CX-5461 As a Therapeutic Strategy For The Cancer-Specific Activation Of p53 In Highly Refractory Haematological Malignancies

    Nadine Hein, PhD, Sean O'Brien, Ph.D., Denis Drygin, PhD, Simon J. Harrison, MBBS MRCP (uk) MRCPath (uk) PhD, Amit Khot, MD, FRCPath, MBBS, MRCP, Carleen Cullinane, PhD, Matthews Geoff, PhD, Marta Chesi, PhD, Peter Leif Bergsagel, MD, Johannes Zuber, MD, Scott W. Lowe, Ph.D., Ricky W Johnstone, PhD, Rick Pearson, PhD, Grant A. McArthur, MD, PhD, FRACP, MBBS, Ross D Hannan, PhD
    Journal: Blood
    Blood (2013) 122 (21): 3941.
    https://doi.org/10.1182/blood.V122.21.3941.3941
    Published: 2013

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