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Journal Articles

Nascent Transcript and Single Cell Rnaseq Analysis Defines the Mechanism of Action of the LSD1 Inhibitor INCB059872 in Myeloid Leukemia

Gretchen Johnston, Haley E. Ramsey, PhDMSc, Kristy Stengel, PhD, Shilpa Sampathi, PhD, Pankaj Acharya, PhD, Maria Arrate, MSc, Matthew C. Stubbs, PhD, Timothy Burn, PhD, Scott Hiebert, PhD, Michael R. Savona, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2509.
https://doi.org/10.1182/blood-2019-130458
Published: 2019
Journal Articles

The BET Inhibitor INCB054329 Primes AML Cells for Venetoclax-Induced Apoptosis

Haley Ramsey, PhD MSc, Susu Zhang, Yue Zhao, PhD, Melissa Ann Fischer, PhD, Agnieszka Ewa Gorska, MSc, Maria Arrate, MSc, Londa Fuller, Dalton Greenwood, Matthew C. Stubbs, PhD, Phillip Liu, PhD, Jeffrey C Rathmell, PhD, Scott Hiebert, PhD, Michael R. Savona, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4074.
https://doi.org/10.1182/blood-2018-99-111393
Published: 2018
Journal Articles

Therapeutic Targeting of HDAC3 in FOXO1-Mutant DLBCL

Kristy Stengel, PhD, Srividya Bhaskara, PhD, Jing Wang, PhD, Qi Liu, PhD, Scott Hiebert, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 311.
https://doi.org/10.1182/blood.V130.Suppl_1.311.311
Published: 2017
Journal Articles

Histone Deacetylase Inhibitors Mimic BET Inhibitors and Cause RNA Polymerase Pausing at MYC, KIT, and Other Oncogenes in t(8;21) AML

Pankaj Acharya, PhD, Shilpa Sampathi, PhD, Yue Zhao, PhD, Jing Wang, PhD, Qi Liu, PhD, Kristy Stengel, PhD, Scott Hiebert, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2470.
https://doi.org/10.1182/blood.V130.Suppl_1.2470.2470
Published: 2017
Journal Articles

The CDK7 Inhibitor THZ1 Alters RNA Polymerase Dynamics at the 5' and 3' Ends of Genes

Shilpa Sampathi, PhD, Pankaj Acharya, PhD, Yue Zhao, PhD, Jing Wang, PhD, Kristy Stengel, PhD, Qi Liu, PhD, Michael R. Savona, MD, Scott Hiebert, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1195.
https://doi.org/10.1182/blood.V130.Suppl_1.1195.1195
Published: 2017
Journal Articles

High Resolution Mapping of Active RNA Polymerases Identifies KIT As a Target of BET Inhibitors in t(8;21) AML

Yue Zhao, PhD, Phillip Liu, PhD, Peggy Scherle, PhD, Reid Huber, PhD, Michael R. Savona, MD, Scott Hiebert, PhD
Journal: Blood
Blood (2015) 126 (23): 1225.
https://doi.org/10.1182/blood.V126.23.1225.1225
Published: 2015
Journal Articles

Eto2/MTG16 Regulates E-Protein Activity and Subset Specification in Dendritic Cell Development

Hiyaa Singhee Ghosh, Ph.D, Kang Liu, PhD, Scott Hiebert, PhD, Boris Reizis, PhD
Journal: Blood
Blood (2012) 120 (21): 1229.
https://doi.org/10.1182/blood.V120.21.1229.1229
Published: 2012
Journal Articles

Myeloid Translocation Gene (MTG)-16 Binds Intracellular Domains of Notch Receptors to Coordinate Notch-Dependent Cell Fate Specification.

Michael E Engel, MD, PhD, Hong Nguyen, PhD, Jolene Mariotti, BS, Aubrey A Hunt, BS, Scott Hiebert, PhD
Journal: Blood
Blood (2009) 114 (22): 257.
https://doi.org/10.1182/blood.V114.22.257.257
Published: 2009
Journal Articles

MTG16, a Target of the T(16;21) in Acute Myeloid Leukemia, Is Required for Hematopoietic Stem and Progenitor Cell Functions

Melissa Ann Steapleton, Isabel Moreno, PhD, Brenda Chyla, PhD, Scott Hiebert, PhD
Journal: Blood
Blood (2008) 112 (11): 609.
https://doi.org/10.1182/blood.V112.11.609.609
Published: 2008
Journal Articles

Myeloid Translocation Gene 16 (MTG16) Regulates Lymphopoiesis

Aubrey A Hunt, Melissa Ann Steapleton, Isabel Moreno, PhD, Scott Hiebert, PhD
Journal: Blood
Blood (2008) 112 (11): 2466.
https://doi.org/10.1182/blood.V112.11.2466.2466
Published: 2008
Journal Articles

RUNX1/AML1 DNA Binding Domain and ETO/MTG8 NHR2 Dimerization Domain Are Critical to AML1−ETO9a Leukemogenesis.

Ming Yan, PhD, Scott Hiebert, PhD, Dong-Er Zhang, PhD
Journal: Blood
Blood (2006) 108 (11): 772.
https://doi.org/10.1182/blood.V108.11.772.772
Published: 2006