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Journal Articles

Open ADAMTS13 Conformation in Immune-Mediated Thrombotic Thrombocytopenic Purpura Is Induced By Anti-ADAMTS13 Autoantibodies and Corresponds with an Ongoing ADAMTS13 Pathology

Blood (2018) 132 (Supplement 1): 222.

https://doi.org/10.1182/blood-2018-99-113762

Published: 2018

Journal Articles

The Macrophage-Specific CD163 Is an Endocytic Receptor for Von Willebrand Factor (VWF) Cleaving Protease ADAMTS13

Fabian Verbij, MSc, Nicoletta Sorvillo, PhD, Paul Kaijen, Johana Hrdinova, MSc, Rob Fijnheer, MD PhD, Anja ten Brinke, PhD, Alexander B. Meijer, PhD, Floris P. van Alphen, BSc, Timo K. van der Berg, Dr., Jonas H. Graversen, Soren K. Moestrup, MD PhD, Jan Voorberg, PhD

Blood (2016) 128 (22): 17.

https://doi.org/10.1182/blood.V128.22.17.17

Published: 2016

Journal Articles

Detection of Platelet Autoantibodies Revisited to Identify Immune Thrombocytopenia

Leendert Porcelijn, MD, Elly Huiskes, Gonda Oldert, Rob Fijnheer, MD PhD, Martin R. Schipperus, MD PhD, Jaap Jan Zwaginga, MD PhD, Masja De Haas, Prof, MD

Blood (2015) 126 (23): 1142.

https://doi.org/10.1182/blood.V126.23.1142.1142

Published: 2015

Journal Articles

ADAMTS13 Reactive CD4+ T Cells Targeting CUB-2 Domain Derived Peptides in Autoimmune Thrombotic Thrombocytopenic Purpura

Fabian Verbij, MSc, Femke de Heij, Annelies Turksma, PhD, Paul Kaijen, Rob Fijnheer, MD PhD, Nicoletta Sorvillo, PhD, Anja ten Brinke, PhD, Jan Voorberg, PhD

Blood (2015) 126 (23): 107.

https://doi.org/10.1182/blood.V126.23.107.107

Published: 2015

Journal Articles

Human Antibodies with Specificity for the Spacer Domain of ADAMTS13 Are Derived from VH1-69 Germline Genes.

Wouter Pos, MSc, Brenda M. Luken, PhD, Johanna Kremer-Hovinga, MD, PhD, Ellen A.M. Turenhout, Roy Jefferis, PhD, Jing-fei Dong, MD, PhD, Rob Fijnheer, MD, PhD, Jan Voorberg, PhD

Blood (2007) 110 (11): 2158.

https://doi.org/10.1182/blood.V110.11.2158.2158

Published: 2007

Journal Articles

Beta2-Glycoprotein I Interferes with von Willebrand Factor-Dependent Platelet Adhesion.

Peter J. Lenting, PhD, Janine J. Hulstein, PhD, Bas de Laat, PhD, Ronald H. Derksen, MD,PhD, Rob Fijnheer, MD,PhD, Philip G. de Groot, PhD

Blood (2006) 108 (11): 415.

https://doi.org/10.1182/blood.V108.11.415.415

Published: 2006

Journal Articles

Characterization of a Human Monoclonal Antibody Directed Against the Spacer Domain of ADAMTS13; a Prototype of Antibodies Present in Patients with Acquired Thrombotic Thrombocytopenic Purpura.

Brenda M. Luken, PhD, Ellen A.M. Turenhout, Paul H.P. Kaijen, Johanna A. Kremer Hovinga, MD, Jan A. Van Mourik, PhD, Rob Fijnheer, MD, PhD, Jan Voorberg, PhD

Blood (2006) 108 (11): 1069.

https://doi.org/10.1182/blood.V108.11.1069.1069

Published: 2006

Journal Articles

Amino Acid Regions 572–579 and 657–666 of the Spacer Domain of ADAMTS13 Provide a Common Antigenic Core Required for Binding of Antibodies in Patients with Acquired TTP.

Brenda M. Luken, MSc, Ellen A.M. Turenhout, Paul H.P. Kaijen, Rob Fijnheer, MD, PhD., Jan Voorberg, PhD.

Blood (2005) 106 (11): 59.

https://doi.org/10.1182/blood.V106.11.59.59

Published: 2005

Journal Articles

Pulmonary Complications after T-Cell Depleted Allogeneic Stem Cell Transplantation: Low Incidence and Strong Association with Acute GVHD.

Cynthia Huisman, MD, PhD, Hanneke M. van der Straaten, MD, Marijke R. Canninga-van Dijk, MD, Rob Fijnheer, MD, PhD, Leo F. Verdonck, MD, PhD

Blood (2005) 106 (11): 1821.

https://doi.org/10.1182/blood.V106.11.1821.1821

Published: 2005

Journal Articles

Multiple B Cell Clones Producing Antibodies Directed to the Spacer and Disintegrin/TSR1 Domains of ADAMTS13 in a Patient with Acquired TTP.

Brenda M. Luken, MSc, Paul H.P. Kaijen, Ellen A.M. Turenhout, Rob Fijnheer, MD, PhD, Jan Voorberg, PhD

Blood (2004) 104 (11): 257.

https://doi.org/10.1182/blood.V104.11.257.257

Published: 2004

NARROW

Open ADAMTS13 Conformation in Immune-Mediated Thrombotic Thrombocytopenic Purpura Is Induced By Anti-ADAMTS13 Autoantibodies and Corresponds with an Ongoing ADAMTS13 Pathology

The Macrophage-Specific CD163 Is an Endocytic Receptor for Von Willebrand Factor (VWF) Cleaving Protease ADAMTS13

Detection of Platelet Autoantibodies Revisited to Identify Immune Thrombocytopenia

ADAMTS13 Reactive CD4+ T Cells Targeting CUB-2 Domain Derived Peptides in Autoimmune Thrombotic Thrombocytopenic Purpura

Human Antibodies with Specificity for the Spacer Domain of ADAMTS13 Are Derived from VH1-69 Germline Genes.

Beta2-Glycoprotein I Interferes with von Willebrand Factor-Dependent Platelet Adhesion.

Characterization of a Human Monoclonal Antibody Directed Against the Spacer Domain of ADAMTS13; a Prototype of Antibodies Present in Patients with Acquired Thrombotic Thrombocytopenic Purpura.

Amino Acid Regions 572–579 and 657–666 of the Spacer Domain of ADAMTS13 Provide a Common Antigenic Core Required for Binding of Antibodies in Patients with Acquired TTP.

Pulmonary Complications after T-Cell Depleted Allogeneic Stem Cell Transplantation: Low Incidence and Strong Association with Acute GVHD.

Multiple B Cell Clones Producing Antibodies Directed to the Spacer and Disintegrin/TSR1 Domains of ADAMTS13 in a Patient with Acquired TTP.

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American Society of Hematology

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American Society of Hematology

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