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Ralph D Sanderson, PhD
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Journal Articles

Roneparstat (SST0001), an Innovative Heparanase (HPSE) Inhibitor for Multiple Myeloma (MM) Therapy: First in Man Study

Monica Galli, MD, Hila Magen, MD, Hermann Einsele, Manik Chatterjee, MD, Mariella Grasso, MD, Giorgina Specchia, Paola Barbieri, MD, David Paoletti, MS, Silvia Pace, MS, Ralph D Sanderson, PhD, Alessandro Rambaldi, MD, Arnon Nagler, MD MSc
Journal: Blood
Blood (2015) 126 (23): 3246.
https://doi.org/10.1182/blood.V126.23.3246.3246
Published: 2015
Journal Articles

Runx2 Transcription Factor Regulates Heparanase-Induced Bone Resorption in Multiple Myeloma

Li Nan, Haiyan Chen, Jian Ruan, MD, Rebecca S Sollie, Cara Schafer, Francis T Crittenden, Anurag Purushothaman, PhD, Ralph D. Sanderson, PhD, Amjad Javed, PhD, Yang Yang, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 567.
https://doi.org/10.1182/blood.V120.21.567.567
Published: 2012
Journal Articles

Heparanase Regulates Response to Proteasomal Inhibition in Myeloma

Vishnu Prakash C. Ramani, PhD, Ralph D. Sanderson, PhD
Journal: Blood
Blood (2012) 120 (21): 4902.
https://doi.org/10.1182/blood.V120.21.4902.4902
Published: 2012
Journal Articles

A Heparin-Based Inhibitor of Heparanase Blocks Myeloma Growth In Vivo by Targeting the Tumor Microenvironment.

Yang Yang, MD, PhD, Telisha Swain, BA, Annamaria Naggi, PhD, Giangiacomo Torri, PhD, Benito Casu, PhD, Israel Vlodavsky, PhD, Ralph D. Sanderson, PhD
Journal: Blood
Blood (2007) 110 (11): 1502.
https://doi.org/10.1182/blood.V110.11.1502.1502
Published: 2007
Journal Articles

Expression of Soluble Syndecan-1 or Heparanase by Myeloma Cells Enhances Levels of Angiogenic Growth Factors Present in Endothelial Cells.

Yang Yang, MD, PhD, Ashley Elizabeth Frith, Allison Theus, Veronica Macleod, MS, Ralph D. Sanderson, PhD
Journal: Blood
Blood (2006) 108 (11): 3448.
https://doi.org/10.1182/blood.V108.11.3448.3448
Published: 2006
Journal Articles

Extracellular Endosulfatases (Sulfs) Inhibit Myeloma Tumor Growth In Vivo .

Yuemeng Dai, MD, PhD, Yang Yang, MD, PhD, Veronica MacLeod, MS, Xinping Yue, PhD, Alan C. Rapraeger, PhD, Zachary Shriver, PhD, Ganesh Venkataraman, PhD, Ram Sasisekharan, PhD, Ralph D. Sanderson, PhD
Journal: Blood
Blood (2005) 106 (11): 3386.
https://doi.org/10.1182/blood.V106.11.3386.3386
Published: 2005
Journal Articles

Heparanase Upregulates Synthesis and Expression of Syndecan-1 (CD138) - A Novel Growth Regulatory Loop for Myeloma Tumors.

Yang Yang, MD, PhD, Veronica MacLeod, MS, Allison M. Theus, BS, Ralph D. Sanderson, PhD, Fenghuang Zhan, MD, PhD, John Shaughnessy, Jr., PhD
Journal: Blood
Blood (2005) 106 (11): 625.
https://doi.org/10.1182/blood.V106.11.625.625
Published: 2005
Journal Articles

Heparanase Promotes the Spontaneous Metastasis of Myeloma Cells to Bone.

Yang Yang, MD, PhD, Veronica MacLeod, MS, Manali Bendre, PhD, Yan Huang, Allison M. Theus, BA, Hua-Quan Miao, PhD, Paul Kussie, PhD, Shmuel Yaccoby, PhD, Joshua Epstein, DSc, Larry J. Suva, PhD, Thomas Kelly, PhD, Ralph D. Sanderson, PhD
Journal: Blood
Blood (2004) 104 (11): 635.
https://doi.org/10.1182/blood.V104.11.635.635
Published: 2004