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Journal Articles

Disease Burden Impacts Outcomes in Pediatric and Young Adult B-Cell Acute Lymphoblastic Leukemia after Commercial Tisagenlecleucel: Results from the Pediatric Real World CAR Consortium (PRWCC)

Blood (2020) 136 (Supplement 1): 14–15.

https://doi.org/10.1182/blood-2020-134472

Published: 2020

Journal Articles

Real-World Treatment of Pediatric Patients with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia Using Tisagenlecleucel That Is out of Specification for Commercial Release

Blood (2020) 136 (Supplement 1): 42–44.

https://doi.org/10.1182/blood-2020-136674

Published: 2020

Journal Articles

Health Care Utilization and Cost of Allogeneic Hematopoietic Cell Transplantation in Children with Malignant and Non-Malignant Diseases

Angela Ricci, MD, Zhezhen Jin, PhD, Wallace Bourgeois, MD, Matt Hall, PhD, Prakash Satwani, MD

Blood (2017) 130 (Supplement 1): 2109.

https://doi.org/10.1182/blood.V130.Suppl_1.2109.2109

Published: 2017

Journal Articles

Role of Donor Source on Clinical Outcomes and Inpatient Resource Utilization for Hematopoietic Cell Transplantation in Children with Acute Leukemia

Staci D Arnold, MD MBA, Ruta Brazauskas, PhD, Naya He, MPH, Yimei Li, PhD, Prakash Satwani, MD MBBS, Michael A Pulsipher, MD, Matt Hall, PhD, Yoshiko Atsuta, MD PhD, Jignesh D Dalal, MD, Theresa Hahn, PhD, Carmem Bonfim, MD, Nandita Khera, MD, Richard Aplenc, MD PhD, Wael Saber, MD MS

Blood (2016) 128 (22): 3575.

https://doi.org/10.1182/blood.V128.22.3575.3575

Published: 2016

Journal Articles

A Study of Predictors of Clinical Outcomes and Healthcare Utilization in Children with Sickle Cell Disease Undergoing Allogeneic Hematopoietic Cell Transplantation

Prakash Satwani, MD MBBS, Ruta Brazauskas, PhD, Staci D. Arnold, MD MBA, Naya He, PhD, Yimei Li, PhD, Richard Aplenc, MD PhD, Matt Hall, PhD, Yoshiko Atsuta, MDPhD, Jignesh D Dalal, MD, Theresa Hahn, PhD, ZheZhen Jin, PhD, Carmem Sales-Bonfim, MD PhD, Nandita Khera, MD, Wael Saber, MD MS

Blood (2015) 126 (23): 528.

https://doi.org/10.1182/blood.V126.23.528.528

Published: 2015

Journal Articles

Romedepsin (RM), a Histone Deacytelase Inhibitor (HDACi), Significantly Increases the Expression of NKG2D Ligands, MIC A/B, In Pediatric Leukemia/Lymphoma Cells (LL), Resulting In Enhanced In Vitro and In Vivo NK Cytotoxicity In NOD-SCID Mice: Translational Approach for Adoptive NK Cell Targeted Immunotherapy

Prakash Satwani, MD, Aniket Saha, MD, Sejal Bavishi, BS, Frances Zhao, MS, Janet Ayello, MS, MT(ASCP), Carmella van de Ven, MA, Mitchell S. Cairo, MD

Blood (2010) 116 (21): 4297.

https://doi.org/10.1182/blood.V116.21.4297.4297

Published: 2010

Journal Articles

A Pilot Study of Reduced Toxicity Conditioning (RTC) with Busulfan (Bu), Fludarabine (Flu), and Alemtuzumab Followed by Allogeneic Stem Cell Transplantation (AlloSCT) to Induce Sustained Mixed Donor Chimerism In Patients with Symptomatic Sickle Cell Disease (SCD)

Monica Bhatia, MD, Mark B Geyer, AB, Courtney Baker, RN, MSN, PNP, Erin Morris, RN, BSN, Deirdre Duffy, BS, Diane George, MD, James H Garvin, Jr., MD, PhD, Prakash Satwani, MD, Joseph Schwartz, MD, Sandra Foley, CPNP, Ria Hawks, CPNP, Elana Hamburger-Smilow, CPNP, Lee Ann Baxter-Lowe, PhD, Mitchell S. Cairo, MD

Blood (2010) 116 (21): 3504.

https://doi.org/10.1182/blood.V116.21.3504.3504

Published: 2010

Journal Articles

Dose Escalation of Clofarabine In Combination with Cytarabine and Total Body Irradiation (TBI) Followed by Allogeneic Stem Cell Transplantation (AlloSCT) In Children, Adolescents and Young Adults (CAYA) with Poor-Risk Acute Leukemia

Mark B Geyer, AB, Angela M Ricci, BA, Lauren Harrison, RN, MSN, Deirdre Duffy, BS, Monica Bhatia, MD, James H Garvin, Jr., MD, Diane George, MD, Prakash Satwani, MD, Alexandra C Cheerva, MD, MS, Julie Talano, MD, Fevzi Ozkaynak, MD, Theodore B. Moore, MD, MS, Joseph Schwartz, MD, Lee Ann Baxter-Lowe, PhD, Mitchell S. Cairo, MD

Blood (2010) 116 (21): 36.

https://doi.org/10.1182/blood.V116.21.36.36

Published: 2010

Journal Articles

Differential Genomic and Proteomic Signatures In Cord Blood (CB) Vs Peripheral Blood (PB) CD56 +Dim NK Cells: Over Expression of CD34 In CB Vs PB CD56 +Dim NK Cells

Nancy S Day, PhD, Evan Shereck, MD, Janet Ayello, MS, MT(ASCP), Catherine McGuinn, MD, Prakash Satwani, MD, Juliana Atallah, Carmella van de Ven, MA, Ronald J Wapner, MD, Megan S. Lim, MD, PhD, Mitchell S. Cairo, MD

Blood (2010) 116 (21): 2781.

https://doi.org/10.1182/blood.V116.21.2781.2781

Published: 2010

Journal Articles

Romedepsin (RM), a HDACi, Significantly Increases the Expression of NKG2D Ligands, MIC A/B, in Leukemia/Lymphoma Cells (LL), in Part through the Glycogen Synthase Kinase-3 (GSK-3) Pathway, Resulting in Enhanced NK Cytotoxicity.

Aniket Saha, MD, Sejal Bavishi, B.S., Frances Zhao, Janet Ayello, MS, MT, Carmella van de Ven, MA, Prakash Satwani, MD, Mitchell S. Cairo, MD

Blood (2009) 114 (22): 3027.

https://doi.org/10.1182/blood.V114.22.3027.3027

Published: 2009

Journal Articles

Reduced Toxicity Conditioning (RTC) Compared to Myeloablative Conditioning (MAC) Prior to Unrelated Cord Blood Transplantation (UCBT) in Pediatric Recipients Was Associated with Similar but Also Delayed Time to Immune Reconstitution and a Concomitant Significant Decrease in Grade II-IV Agvhd.

Jason Freedman, M.D., Diane George, MD, Judith Jacobson, DrPH, MBA, Mark Geyer, AB, Carmella van de Ven, MA, Nathifa Fearon, RN, MSN, Claire Fanelli, RN, BSN, Bradford Tallamy, BA, Prakash Satwani, MD, Monica Bhatia, MD, James H. Garvin, Jr., MD, M. Brigid Bradley, MD, Tracey Schonfeld, RN, BSN, Lauren Harrison, RN, Erin Morris, RN, Joseph Schwartz, MD, Lee Ann Baxter-Lowe, PhD, Mitchell S. Cairo, MD

Blood (2009) 114 (22): 2304.

https://doi.org/10.1182/blood.V114.22.2304.2304

Published: 2009

Journal Articles

Enhanced Natural Killer (NK) and NK T Cell Activation, Expansion and Cytokine Protein Production Following Ex-Vivo Engineering (EvE) of Cryopreserved Umbilical Cord Blood (UCB): Potential Role of CB NK and NKT Cells in Adoptive Cellular Immunotherapy (ACI).

Janet Ayello, MS, Prakash Satwani, MD, Carmella van de Ven, MA, Laxmi Baxi, MD, Ronald Wapner, MD, Etan Sugarman, BA, Mitchell S. Cairo, MD

Blood (2007) 110 (11): 1206.

https://doi.org/10.1182/blood.V110.11.1206.1206

Published: 2007

Journal Articles

Immunophenotypic and Proteomic Characterization of Cord Blood (CB) CD56 dim Versus Peripheral Blood (PB) CD56 dim NK Cells.

Evan Shereck, MD, Nancy Day, PhD, Catherine McGuinn, MD, Prakash Satwani, MD, Carmella van de Ven, MA, Janet Ayello, MS, David Crockett, MS, Ronald J. Wapner, MD, Kojo Elenitoba-Johnson, MD, Megan Lim, MD, PhD, Mitchell S. Cairo, MD

Blood (2007) 110 (11): 3879.

https://doi.org/10.1182/blood.V110.11.3879.3879

Published: 2007

Journal Articles

Peripheral Blood (PB) CD56 bright and CD56 dim Do Not Exhibit Differences in NKR Expression Compared to Their Cord Blood (CB) Counterparts: CB CD56 dim May Represent an Intermediary between CB CD56 bright and PB CD56 dim .

Evan Shereck, MD, Prakash Satwani, MD, Carmella van de Ven, Janet Ayello, Ronald J. Wapner, MD, Nancy Day, PhD, Hong Jiang, PhD, Mitchell S. Cairo, MD

Blood (2006) 108 (11): 5155.

https://doi.org/10.1182/blood.V108.11.5155.5155

Published: 2006

Journal Articles

Aberrant Expression of IL-2R in Pediatric Anaplastic Large Cell Lymphoma: Cellular and Proteomic Analysis of Denileukin Diftitox (ONTAK) as a Potential Therapeutic Agent.

Megan S. Lim, MD, PhD, Jaqueline Tygeson, Charles Seiler, David K. Crockett, Prakash Satwani, MD, Sherrie L. Perkins, MD, PhD, Mitchell S. Cairo, MD, Kojo S. Elenitoba-Johnson, MD

Blood (2006) 108 (11): 2051.

https://doi.org/10.1182/blood.V108.11.2051.2051

Published: 2006

Journal Articles

Optimal Ex-Vivo Expansion (EvE) of Cord Blood (CB) Natural Killer (NK) Cells, NK Cytotoxicity and NK Receptor (NKR) Expression: Potential for CB Adoptive Cellular Immunotherapy (ACI).

Janet Ayello, Prakash Satwani, MD, Carmella Van de Ven, Elizabeth Roman, MD, Laxmi Baxi, MD, Joanne Kurtzburg, MD, Mitchell S. Cairo, MD

Blood (2005) 106 (11): 34.

https://doi.org/10.1182/blood.V106.11.34.34

Published: 2005

Journal Articles

Characterization and Comparison of Cord Blood (CB) vs Adult Peripheral Blood (APB) CD4 + CD25 + NAÏVE and Antigen Presentation Cell (APC) Induced T Regulatory (TREG): Significant Increase in APC Induced CB vs APB CD4 + /CD25 + /CTLA-4 + TREG.

Chih-Chao Chang, PhD, Carmella van de Ven, MA, Prakash Satwani, MD, Nora Oberfeld, BS, Lynn Simpson, MD, Mitchell S. Cairo, MD

Blood (2004) 104 (11): 4974.

https://doi.org/10.1182/blood.V104.11.4974.4974

Published: 2004

Journal Articles

Differential Expression of Genes Associated with Toll-Like Receptor-4 (TLR4) Signal Transduction Pathway in Lipopolysaccharide (LPS)-Activated Cord Blood (CB) vs. Adult Peripheral Blood (APB) Monocyte (Mo)-Derived Dendritic Cells (DC).

Hong Jiang, PhD, Mary Brigid Bradley, MD, Carmella van de Ven, Prakash Satwani, MD, Laxmi Baxi, MD, Mitchell S. Cairo, MD

Blood (2004) 104 (11): 3444.

https://doi.org/10.1182/blood.V104.11.3444.3444

Published: 2004

Journal Articles

Dysregulation of Interleukin (IL)-18 Gene Expression and Protein Production in Basal and Activated Cord Blood (CB) vs. Peripheral Blood (PB) Mononuclear Cells and Differential Effects of IL-18 in CB vs. PB T and NK Cell Immunity.

Prakash Satwani, MD, Janet Ayello, MS, Lynn Simpson, MD, Carmella van de Ven, MA, Mitchell S. Cairo, MD

Blood (2004) 104 (11): 2660.

https://doi.org/10.1182/blood.V104.11.2660.2660

Published: 2004

Journal Articles

Prolonged Ex Vivo Expansion (7–10 Days) of Cord Blood (CB) Recryopreserved and Rethawed Aliquots with Anti-CD3, IL-2, IL-12 Significantly Expands NKT Cells, NKT KIR Substes and NK Cytotoxicity Compared to Short-Term Expansion: Potential for CB Adoptive Cellular Immunotherapy (ACI).

Janet Ayello, MS, Prakash Satwani, MD, Carmella van de Ven, MA, Elizabeth Roman, MD, Allison O’Neill, Max Shutran, Matthew Greenhawt, MD, Laxmi Baxi, MD, Lynn Simpson, MD, Joanne Kurtzberg, MD, Mitchell S. Cairo, MD

Blood (2004) 104 (11): 2845.

https://doi.org/10.1182/blood.V104.11.2845.2845

Published: 2004

NARROW

Disease Burden Impacts Outcomes in Pediatric and Young Adult B-Cell Acute Lymphoblastic Leukemia after Commercial Tisagenlecleucel: Results from the Pediatric Real World CAR Consortium (PRWCC)

Real-World Treatment of Pediatric Patients with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia Using Tisagenlecleucel That Is out of Specification for Commercial Release

Health Care Utilization and Cost of Allogeneic Hematopoietic Cell Transplantation in Children with Malignant and Non-Malignant Diseases

Role of Donor Source on Clinical Outcomes and Inpatient Resource Utilization for Hematopoietic Cell Transplantation in Children with Acute Leukemia

A Study of Predictors of Clinical Outcomes and Healthcare Utilization in Children with Sickle Cell Disease Undergoing Allogeneic Hematopoietic Cell Transplantation

A Pilot Study of Reduced Toxicity Conditioning (RTC) with Busulfan (Bu), Fludarabine (Flu), and Alemtuzumab Followed by Allogeneic Stem Cell Transplantation (AlloSCT) to Induce Sustained Mixed Donor Chimerism In Patients with Symptomatic Sickle Cell Disease (SCD)

Dose Escalation of Clofarabine In Combination with Cytarabine and Total Body Irradiation (TBI) Followed by Allogeneic Stem Cell Transplantation (AlloSCT) In Children, Adolescents and Young Adults (CAYA) with Poor-Risk Acute Leukemia

Differential Genomic and Proteomic Signatures In Cord Blood (CB) Vs Peripheral Blood (PB) CD56 +Dim NK Cells: Over Expression of CD34 In CB Vs PB CD56 +Dim NK Cells

Romedepsin (RM), a HDACi, Significantly Increases the Expression of NKG2D Ligands, MIC A/B, in Leukemia/Lymphoma Cells (LL), in Part through the Glycogen Synthase Kinase-3 (GSK-3) Pathway, Resulting in Enhanced NK Cytotoxicity.

Reduced Toxicity Conditioning (RTC) Compared to Myeloablative Conditioning (MAC) Prior to Unrelated Cord Blood Transplantation (UCBT) in Pediatric Recipients Was Associated with Similar but Also Delayed Time to Immune Reconstitution and a Concomitant Significant Decrease in Grade II-IV Agvhd.

Enhanced Natural Killer (NK) and NK T Cell Activation, Expansion and Cytokine Protein Production Following Ex-Vivo Engineering (EvE) of Cryopreserved Umbilical Cord Blood (UCB): Potential Role of CB NK and NKT Cells in Adoptive Cellular Immunotherapy (ACI).

Immunophenotypic and Proteomic Characterization of Cord Blood (CB) CD56 dim Versus Peripheral Blood (PB) CD56 dim NK Cells.

Peripheral Blood (PB) CD56 bright and CD56 dim Do Not Exhibit Differences in NKR Expression Compared to Their Cord Blood (CB) Counterparts: CB CD56 dim May Represent an Intermediary between CB CD56 bright and PB CD56 dim .

Aberrant Expression of IL-2R in Pediatric Anaplastic Large Cell Lymphoma: Cellular and Proteomic Analysis of Denileukin Diftitox (ONTAK) as a Potential Therapeutic Agent.

Optimal Ex-Vivo Expansion (EvE) of Cord Blood (CB) Natural Killer (NK) Cells, NK Cytotoxicity and NK Receptor (NKR) Expression: Potential for CB Adoptive Cellular Immunotherapy (ACI).

Characterization and Comparison of Cord Blood (CB) vs Adult Peripheral Blood (APB) CD4 + CD25 + NAÏVE and Antigen Presentation Cell (APC) Induced T Regulatory (TREG): Significant Increase in APC Induced CB vs APB CD4 + /CD25 + /CTLA-4 + TREG.

Differential Expression of Genes Associated with Toll-Like Receptor-4 (TLR4) Signal Transduction Pathway in Lipopolysaccharide (LPS)-Activated Cord Blood (CB) vs. Adult Peripheral Blood (APB) Monocyte (Mo)-Derived Dendritic Cells (DC).

Dysregulation of Interleukin (IL)-18 Gene Expression and Protein Production in Basal and Activated Cord Blood (CB) vs. Peripheral Blood (PB) Mononuclear Cells and Differential Effects of IL-18 in CB vs. PB T and NK Cell Immunity.

Prolonged Ex Vivo Expansion (7–10 Days) of Cord Blood (CB) Recryopreserved and Rethawed Aliquots with Anti-CD3, IL-2, IL-12 Significantly Expands NKT Cells, NKT KIR Substes and NK Cytotoxicity Compared to Short-Term Expansion: Potential for CB Adoptive Cellular Immunotherapy (ACI).

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American Society of Hematology

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American Society of Hematology

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