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Journal Articles

Targeting β3 Integrin Psi Domain Inhibits Both Platelet Aggregation and Blood Coagulation: Two Birds with One Stone

Tyler W. Stratton, MSc, Guangheng Zhu, MD, Yiming Wang, MD PhD, Pingguo Chen, PhD, Miguel A. D. Neves, PhD MSc, Reid C. Gallant, MSc, Peter A. A. Norris, BSc, John J. Freedman, MD, Heyu Ni, MD MSc, PhD

Blood (2018) 132 (Supplement 1): 1246.

https://doi.org/10.1182/blood-2018-99-119964

Published: 2018

Journal Articles

Maternal Anti-αIIb Antibodies Target Fetal Hematopoietic Stem Cells and May Lead to Pancytopenia and Miscarriage in Fnait

Jade Sullivan, BSc, Brigitta Elaine Oswald, B.Sc, Brian Vadasz, BSc, June Li, MSc, Pingguo Chen, PhD, Mortimer Poncz, MD, John J. Freedman, MD, Heyu Ni, MD MSc, PhD

Blood (2017) 130 (Supplement 1): 233.

https://doi.org/10.1182/blood.V130.Suppl_1.233.233

Published: 2017

Journal Articles

Novel Murine Models Of Fetal and Neonatal Alloimmune Thrombocytopenia Established In αIIb Deficient and Human αIIb Transgenic Mice

Brian Vadasz, BSc, Pingguo Chen, PhD, Yougbare Issaka, PhD, Guangheng Zhu, MD, Frampton Jonathan, Ph.D, Mortimer Poncz, MD, John J. Freedman, MD, Heyu Ni, MD, PhD

Blood (2013) 122 (21): 2314.

https://doi.org/10.1182/blood.V122.21.2314.2314

Published: 2013

Journal Articles

CD8+ T Cells Are Predominantly Protective In a Murine Model Of ITP and Is Required For Effective Steroid Therapy

Li Ma, Elisa K. Simpson, H.B.Sc., June Li, BSc, Guangheng Zhu, MD, Pingguo Chen, PhD, John W. Semple, PhD, John Freedman, MD, Heyu Ni, MD, PhD

Blood (2013) 122 (21): 1076.

https://doi.org/10.1182/blood.V122.21.1076.1076

Published: 2013

Journal Articles

Psi Domain of b3 Integrin Has Endogenous Thiol Isomerase Function and Is a Potential New Target for Anti-Thrombotic Therapy

Guangheng Zhu, MD, Pingguo Chen, PhD, Adili Reheman, MD, June Li, BSc, Heyu Ni, MD, PhD

Blood (2012) 120 (21): 382.

https://doi.org/10.1182/blood.V120.21.382.382

Published: 2012

Journal Articles

Antibody- and Cell-Mediated Immune Thrombocytopenia Are Differentially Sensitive to Intravenous Gammaglobulin Therapy

Leola Chow, PhD, Michael Kim, BSc, Edwin R. Speck, BRT, Rukhsana Aslam, PhD, Michelle Lee Webster, MSc, Pingguo Chen, PhD, Heyu Ni, MD, PhD, John Freedman, MD, John W. Semple, PhD

Blood (2008) 112 (11): 399.

https://doi.org/10.1182/blood.V112.11.399.399

Published: 2008

Journal Articles

Engagement of Fibrinogen and β3 Integrin Is Required for Maintenance of Platelet Intracellular and Cell Surface P-Selectin Expression

Hong Yang, MD, Sean Lang, BSc, Zhimin Zhai, MD, Christopher M. Spring, MSc, Adili Reheman, MD, Pingguo Chen, PhD, Matthew J. Flick, PhD, Jay L. Degen, PhD, Ling Li, MSc, Walter H.A. Kahr, MD, PhD, John Freedman, MD, Heyu Ni, MD, PhD

Blood (2008) 112 (11): 2868.

https://doi.org/10.1182/blood.V112.11.2868.2868

Published: 2008

Journal Articles

Maternal Immune Response to Fetal Platelet GPIbα Causes More Frequent Miscarriage in An Animal Model: A Potential Explanation for Low Reported Incidence of Fetal and Neonatal Immune Thrombocytopenia Mediated by Anti-GPIbα Antibodies.

Conglei Li, MD, Siavash Piran, MSc., Pingguo Chen, PhD, Sean Lang, BSc., Jerry Ware, PhD, Zaverio M. Ruggeri, MD, John Freedman, MD, Heyu Ni, MD, PhD

Blood (2008) 112 (11): 3426.

https://doi.org/10.1182/blood.V112.11.3426.3426

Published: 2008

Journal Articles

Fibronectin Is Not the Only Important Molecule Required for Fibrinogen/VWF-Independent Platelet Aggregation: Study of Thrombosis in a New Strain of Triple Deficient Mice.

Adili Reheman, MD, Yang Hong, M.D., Christopher M. Spring, M.Sc., Pingguo Chen, PhD, Denisa D. Wagner, PhD, Reinhard Fassler, M.D., John Freedman, M.D., Heyu Ni, M.D., PhD

Blood (2006) 108 (11): 1515.

https://doi.org/10.1182/blood.V108.11.1515.1515

Published: 2006

NARROW

Targeting β3 Integrin Psi Domain Inhibits Both Platelet Aggregation and Blood Coagulation: Two Birds with One Stone

Maternal Anti-αIIb Antibodies Target Fetal Hematopoietic Stem Cells and May Lead to Pancytopenia and Miscarriage in Fnait

Novel Murine Models Of Fetal and Neonatal Alloimmune Thrombocytopenia Established In αIIb Deficient and Human αIIb Transgenic Mice

CD8+ T Cells Are Predominantly Protective In a Murine Model Of ITP and Is Required For Effective Steroid Therapy

Psi Domain of b3 Integrin Has Endogenous Thiol Isomerase Function and Is a Potential New Target for Anti-Thrombotic Therapy

Antibody- and Cell-Mediated Immune Thrombocytopenia Are Differentially Sensitive to Intravenous Gammaglobulin Therapy

Engagement of Fibrinogen and β3 Integrin Is Required for Maintenance of Platelet Intracellular and Cell Surface P-Selectin Expression

Maternal Immune Response to Fetal Platelet GPIbα Causes More Frequent Miscarriage in An Animal Model: A Potential Explanation for Low Reported Incidence of Fetal and Neonatal Immune Thrombocytopenia Mediated by Anti-GPIbα Antibodies.

Fibronectin Is Not the Only Important Molecule Required for Fibrinogen/VWF-Independent Platelet Aggregation: Study of Thrombosis in a New Strain of Triple Deficient Mice.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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