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Journal Articles

Biomarker Signatures of Sickle Cell Disease Severity

Mengtian Du, BA, Sarah Van Ness, BA, Victor R. Gordeuk, MD, Mark T Gladwin, MD, Paola Sebastiani, PhD, Martin H. Steinberg, MD

Blood (2017) 130 (Supplement 1): 690.

https://doi.org/10.1182/blood.V130.Suppl_1.690.690

Published: 2017

Journal Articles

Association of FOXO3A Polymorphisms with Hematocrit, LDH and Longevity in Patients with Sickle Cell Anemia from CSSCD, Walk-Phasst, and PUSH Clinical Trials

Harold T Bae, PhD MS, Paola Sebastiani, PhD, Victor R. Gordeuk, MD, Yingze Zhang, PhD, Martin H. Steinberg, MD, Gregory J Kato, MD

Blood (2015) 126 (23): 2176.

https://doi.org/10.1182/blood.V126.23.2176.2176

Published: 2015

Journal Articles

Polymorphisms Associated with the Arab-Indian Haplotype of Sickle Cell Anemia Are Candidate Fetal Hemoglobin Gene Modulators

Vinod Vathipadiekal, PhD, Abdulrahman Alsultan, MD, John Farrell, PhD, A.M Al-Rubaish, Fahad Al-Muhanna, Z Naserullah, A Alsuliman, P.K. Patra, Jacqueline Milton, Lindsay Farrer, David H.K. Chui, MD, Amein Al-Ali, Paola Sebastiani, PhD, Martin H. Steinberg, MD

Blood (2015) 126 (23): 3388.

https://doi.org/10.1182/blood.V126.23.3388.3388

Published: 2015

Journal Articles

A Candidate Trans-Acting Modulator of Fetal Hemoglobin Gene Expression in the Arab-Indian Haplotype of Sickle Cell Anemia

Blood (2015) 126 (23): 409.

https://doi.org/10.1182/blood.V126.23.409.409

Published: 2015

Journal Articles

Genes Associated with Alloimmunization to Blood Group Antigens in Sickle Cell Disease

Jacqueline N. Milton, PhD, Allison E. Ashley-Koch, PhD, Melanie E. Garrett, MS, Karen L. Soldano, B.S., Eugene P. Orringer, MD, Paola Sebastiani, PhD, Daniel A. Dworkis, MD PhD, Karen Quillen, MD MPH, Martin H. Steinberg, MD, Marilyn J. Telen, MD

Blood (2014) 124 (21): 762.

https://doi.org/10.1182/blood.V124.21.762.762

Published: 2014

Journal Articles

BCL11A enhancer Haplotypes Are Associated with the Distribution of HbF in Arab-Indian and African Haplotype Sickle Cell Anemia but Not the Different Population Levels of HbF

Paola Sebastiani, PhD, John J. Farrell, PhD, Shuai Wang, MS, Heather L Edward, BA, Heather M. Shappell, BS, Harold T. Bae, PhD, Clinton T. Baldwin, PhD, A. M. Al-Rubaish, MD, Zaki Naserullah, MD, Ahmed Alsuliman, MD, Pradeep K. Patra, PhD, Lindsay A. Farrer, PhD, David H.K. Chui, MD, Abdulrahman Alsultan, MD, Duyen A. Ngo, MD, Haifa Kathrin Al-Ali, MD, Martin H. Steinberg, MD

Blood (2014) 124 (21): 4066.

https://doi.org/10.1182/blood.V124.21.4066.4066

Published: 2014

Journal Articles

Fetal Hemoglobin In Sickle Cell Anemia: A Glass Half Full?

Martin H. Steinberg, MD, David H.K. Chui, MD, George J. Dover, MD, Paola Sebastiani, PhD, Abdulrahman Alsultan, MD

Blood (2013) 122 (21): 4691.

https://doi.org/10.1182/blood.V122.21.4691.4691

Published: 2013

Journal Articles

Genetic Association Of a MAPK8 Expression Quantitative Trait Locus With Pre-Capillary Pulmonary Hypertension In Sickle Cell Disease

Xu Zhang, PhD, Wei Zhang, PhD, Shwu-Fan Ma, PhD, Ankit A. Desai, MD, Galina Y. Miasnikova, MD, Adelina Sergueeva, MD, Tatiana Ammosova, PhD, Min Xu, Sergei A. Nekhai, PhD, Taimur Abbasi, MD, Nancy G. Casanova, MD, Martin H. Steinberg, MD, Clinton T. Baldwin, PhD, Paola Sebastiani, PhD, Josef Prchal, MD, Rick Kittles, PhD, Joe GN Garcia, MD, Roberto F. Machado, MD, Victor R. Gordeuk, MD

Blood (2013) 122 (21): 991.

https://doi.org/10.1182/blood.V122.21.991.991

Published: 2013

Journal Articles

Prediction of Fetal Hemoglobin in Sickle Cell Anemia Using a Genetic Risk Score

Jacqueline N Milton, MS, Paola Sebastiani, PhD, Clinton T. Baldwin, PhD, Efthymia Melista, Victor R. Gordeuk, MD, Mehdi Nouraie, PhD, Gregory J. Kato, M.D., Caterina Minniti, MD, James G. Taylor, M.D., Andrew Campbell, MD, Lori Luchtman-Jones, MD, Sohail R. Rana, MD, Oswaldo L Castro, MD, Yingze Zhang, PhD, Mark T Gladwin, MD, Martin H. Steinberg, MD

Blood (2012) 120 (21): 3216.

https://doi.org/10.1182/blood.V120.21.3216.3216

Published: 2012

Journal Articles

Induced Pluripotent Stem Cell Modeling of Sickle Cell Anemia

Sarah S Rozelle, Brenden W Smith, Efthymia Melista, Ehimen Aneni, MD, Paola Sebastiani, PhD, Clinton T. Baldwin, PhD, Abdulrahman Alsultan, MD, David H.K. Chui, MD, Gustavo Mostoslavsky, M.D., Ph.D, Martin H. Steinberg, MD, George J. Murphy, Ph.D

Blood (2012) 120 (21): 3233.

https://doi.org/10.1182/blood.V120.21.3233.3233

Published: 2012

Journal Articles

Genetic Determinants of Hemolysis in Sickle Cell Anemia.

Blood (2012) 120 (21): 2104.

https://doi.org/10.1182/blood.V120.21.2104.2104

Published: 2012

Journal Articles

Co-Inheritance of Delta Thalassemia Might Contribute to the High Fetal Hemoglobin in Sickle Cell Anemia Patients with the Saudi-Indian Haplotype

Abdulrahman Alsultan, MD, Duyen A. Ngo, MD, John J. Farrell, MS, Hazem Ghabbour, Idowu Akinsheye, PhD, Amein Al-Ali, PhD, Ahmed Alsuliman, MD, Muneer Al-Baghshi, MD, Waleed Albuali, MD, Mohammed Alabdulaali, MD, Paola Sebastiani, PhD, Clinton T. Baldwin, PhD, David H.K. Chui, MD, Martin H. Steinberg, MD

Blood (2011) 118 (21): 1056.

https://doi.org/10.1182/blood.V118.21.1056.1056

Published: 2011

Journal Articles

Clinical and Genetic Variability of Red Blood Cell Hemolysis in Sickle Cell Anemia

Jacqueline N Milton, MS, Paola Sebastiani, PhD, Yingze Zhang, PhD, Mehdi Nouraie, MD, Janet Lee, MD, Clinton T. Baldwin, PhD, Xuejun Zhao, MD, Zeyu Xiong, MD, Qilu Zeng, MS, Gregory J. Kato, MD, Jonathan C. Goldsmith, MD, James G. Taylor, MD, Onyinye Onyekwere, MD, MS, Victor R. Gordeuk, MD, Roberto F Machado, MD, Martin H Steinberg, MD, Mark T Gladwin, MD

Blood (2011) 118 (21): 1077.

https://doi.org/10.1182/blood.V118.21.1077.1077

Published: 2011

Journal Articles

An Elevated Tricuspid Regurgitant Jet Velocity in Sickle Cell Disease Is Associated with Polymorphisms in Genes Impacting Innate Immunity

Harold T. Bae, Clinton T. Baldwin, PhD, Mark T Gladwin, MD, Allison E Ashley-Koch, PhD, Melanie Garrett, MS, Karen Soldano, B.S., James G. Taylor, MD, Gregory J. Kato, MD, Marilyn J. Telen, MD, Paola Sebastiani, PhD, Martin H. Steinberg, MD, Elizabeth S Klings, MD

Blood (2011) 118 (21): 514.

https://doi.org/10.1182/blood.V118.21.514.514

Published: 2011

Journal Articles

Alterations In HLA-DR Expression In Peripheral Blood Mononuclear Cells Are Associated with An Elevated Tricuspid Regurgitant Jet Velocity and Pulmonary Hypertension of Sickle Cell Disease

Elizabeth Klings, MD, Daniel A Dworkis, Surinder Safaya, PhD, Guihua Li, BA, Lynda Reid, Paola Sebastiani, PhD, Clinton T. Baldwin, PhD, Martin H. Steinberg, MD

Blood (2010) 116 (21): 2640.

https://doi.org/10.1182/blood.V116.21.2640.2640

Published: 2010

Journal Articles

Tumor Necrosis Factor-α Signaling In Sickle Cell Disease: Elevated Biomarker Levels and Genetic Associations with Disease Severity

Daniel A Dworkis, Elizabeth Klings, MD, Nadia Solovieff, Guihua Li, BA, Jacqueline N Milton, Stephen W. Hartley, Efthymia Melista, Jason Parente, Paola Sebastiani, PhD, Martin H. Steinberg, MD, Clinton T. Baldwin, PhD

Blood (2010) 116 (21): 2654.

https://doi.org/10.1182/blood.V116.21.2654.2654

Published: 2010

Journal Articles

Fetal Hemoglobin In Sickle Cell Anemia: Molecular Characterization of Saudi Patients From the Eastern Province

Abdulrahman Alsultan, MD, Idowu Akinsheye, Nadia Solovieff, Hazem Ghabbour, Duyen A. Ngo, MD, Daniel A Dworkis, Clinton T. Baldwin, PhD, Paola Sebastiani, PhD, Lindsay A. Farrer, PhD, Martin H. Steinberg, MD, David H.K. Chui, MD

Blood (2010) 116 (21): 1627.

https://doi.org/10.1182/blood.V116.21.1627.1627

Published: 2010

Journal Articles

A 3-Bp Deletion Between Transcription Factor Binding Motifs In the HBS1L-MYB Intergenic Region on Chromosome 6q23 Is Associated with HbF Expression

John J. Farrell, MS, Richard M. Sherva, PhD, Zhi-yi Chen, PhD, Luo Hong-yuan, MD, PhD, Banjamin F. Chu, MD, Shau Yin Ha, MBBS, Chi Kong Li, MBBS, MD, Anselm C.W. Lee, MBBS, Chi Keung Li, MBBS, Hui Leung Yuen, MBBS, Jason C.C. So, MBBS, Edmond ShiuKwan Ma, MD, FRCP, FRCPath, Li Chong Chan, MD, Vivian Chan, PhD, Paola Sebastiani, PhD, Lindsay A. Farrer, PhD, Clinton T. Baldwin, PhD, Martin H. Steinberg, MD, David H.K. Chui, MD

Blood (2010) 116 (21): 1013.

https://doi.org/10.1182/blood.V116.21.1013.1013

Published: 2010

Journal Articles

Genome-Wide Association Study of Stroke in Sickle Cell Anemia.

Paola Sebastiani, PhD, Jacqueline N. Milton, BS, Nadia Timofeev, MS, Stephen W Hartley, Daniel A Dworkis, BS, Efthymia Melista, BS, Clinton T. Baldwin, PhD, Martin H Steinberg, MD

Blood (2009) 114 (22): 1528.

https://doi.org/10.1182/blood.V114.22.1528.1528

Published: 2009

Journal Articles

A Genome-Wide Association Study of the Alloimmunization Responder Phenotype in Sickle Cell Disease.

Daniel A Dworkis, BS, Nadia Timofeev, MS, Jacqueline N. Milton, BS, Stephen W Hartley, Mayetri Gupta, PhD, Paola Sebastiani, PhD, Clinton T. Baldwin, PhD, Efthymia Melista, BS, Jason Parente, BS, Karen Quillen, MD, Martin H Steinberg, MD

Blood (2009) 114 (22): 2551.

https://doi.org/10.1182/blood.V114.22.2551.2551

Published: 2009

NARROW

Biomarker Signatures of Sickle Cell Disease Severity

Association of FOXO3A Polymorphisms with Hematocrit, LDH and Longevity in Patients with Sickle Cell Anemia from CSSCD, Walk-Phasst, and PUSH Clinical Trials

Polymorphisms Associated with the Arab-Indian Haplotype of Sickle Cell Anemia Are Candidate Fetal Hemoglobin Gene Modulators

A Candidate Trans-Acting Modulator of Fetal Hemoglobin Gene Expression in the Arab-Indian Haplotype of Sickle Cell Anemia

Genes Associated with Alloimmunization to Blood Group Antigens in Sickle Cell Disease

BCL11A enhancer Haplotypes Are Associated with the Distribution of HbF in Arab-Indian and African Haplotype Sickle Cell Anemia but Not the Different Population Levels of HbF

Fetal Hemoglobin In Sickle Cell Anemia: A Glass Half Full?

Genetic Association Of a MAPK8 Expression Quantitative Trait Locus With Pre-Capillary Pulmonary Hypertension In Sickle Cell Disease

Prediction of Fetal Hemoglobin in Sickle Cell Anemia Using a Genetic Risk Score

Induced Pluripotent Stem Cell Modeling of Sickle Cell Anemia

Genetic Determinants of Hemolysis in Sickle Cell Anemia.

Co-Inheritance of Delta Thalassemia Might Contribute to the High Fetal Hemoglobin in Sickle Cell Anemia Patients with the Saudi-Indian Haplotype

Clinical and Genetic Variability of Red Blood Cell Hemolysis in Sickle Cell Anemia

An Elevated Tricuspid Regurgitant Jet Velocity in Sickle Cell Disease Is Associated with Polymorphisms in Genes Impacting Innate Immunity

Alterations In HLA-DR Expression In Peripheral Blood Mononuclear Cells Are Associated with An Elevated Tricuspid Regurgitant Jet Velocity and Pulmonary Hypertension of Sickle Cell Disease

Tumor Necrosis Factor-α Signaling In Sickle Cell Disease: Elevated Biomarker Levels and Genetic Associations with Disease Severity

Fetal Hemoglobin In Sickle Cell Anemia: Molecular Characterization of Saudi Patients From the Eastern Province

A 3-Bp Deletion Between Transcription Factor Binding Motifs In the HBS1L-MYB Intergenic Region on Chromosome 6q23 Is Associated with HbF Expression

Genome-Wide Association Study of Stroke in Sickle Cell Anemia.

A Genome-Wide Association Study of the Alloimmunization Responder Phenotype in Sickle Cell Disease.

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American Society of Hematology

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American Society of Hematology

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