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Journal Articles

Role of Aneuploidy in Transcriptional Regulation and Clinical Prognosis in Relapsed and/or Refractory Multiple Myeloma (RRMM)

Christopher T Su, MD, Liying Chen, MS, Jason Chen, MD, Brian Parkin, MD, Avery Polk, Malathi Kandarpa, PhD, Craig E. Cole, MD, Erica Campagnaro, MD, Josh Vo, PhD, Dan Robinson, PhD, Yi-Mi Wu, PhD, Moshe Talpaz, MD, Jennifer Yesil, MSc, Daniel Auclair, P. Leif Bergsagel, MD, Arul Chinnaiyan, MDPhD, Veerabhadran Baladandayuthapani, PhD, J Christine Ye, MDMSc
Journal: Blood
Blood (2020) 136 (Supplement 1): 45–46.
https://doi.org/10.1182/blood-2020-134558
Published: 2020
Journal Articles

Phase I Trial of Systemic Administration of Vesicular Stomatitis Virus Genetically Engineered to Express NIS and Human Interferon Beta, in Patients with Relapsed or Refractory Multiple Myeloma (MM), Acute Myeloid Leukemia (AML), and T-Cell Neoplasms (TCL)

Joselle Cook, MBBS, Kah-Whye Peng, PhD, Brenda F Ginos, B.A., Amylou C. Dueck, PhD, Marissa Giers, BSN, RN, Nandakumar Packiriswamy, PhD DVM, Beth Brunton, PhD, Mrinal M. Patnaik, MDMBBS, Thomas E. Witzig, MD, Francis K. Buadi, MB, CHB, Angela Dispenzieri, MD, Morie A Gertz, MD, Ronald S. Go, MD, Suzanne R. Hayman, MD, John A. Lust, MD PhD, David Dingli, MD PhD, S. Vincent Rajkumar, MD, Nelson Leung, MD, Rahma M Warsame, MD, Wilson I Gonsalves, MD, Taxiarchis Kourelis, MD, Eli Muchtar, MD, P. Leif Bergsagel, MD, Stephen Broski, MD, Prashant Kapoor, MD, Robert A. Kyle, MD, Mustaqeem A. Siddiqui, MDMBA, Amie Fonder, PA-C, MS, Miriam A. Hobbs, APRN, CNP, DNP, Yi L. Hwa, NP, Yi Lin, MD PhD, Shaji K. Kumar, MD, Stephen J. Russell, MD PhD, Martha Q. Lacy, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 7–8.
https://doi.org/10.1182/blood-2020-140853
Published: 2020
Journal Articles

Phenotypic and Functional Characterization of Multiple Myeloma By Single Cell Mass Cytometry (CyTOF)

Linda B Baughn, PhD, Erik Jessen, PhD, Matthew Smith, Neeraj Sharma, PhD, Joselle Cook, MBBS, Surendra Dasari, PhD, Kathryn E. Pearce, MS, Nathalie Meurice, PhD, Michael A. Linden, MDPhD, A. Keith Stewart, MB, ChB, P. Leif Bergsagel, MD, Brian G. Van Ness, PhD, Shaji K. Kumar, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40–41.
https://doi.org/10.1182/blood-2020-141639
Published: 2020
Journal Articles

Phase 2 Trial of Ixazomib, Cyclophosphamide and Dexamethasone for Treatment of Previously Untreated Light Chain Amyloidosis

Eli Muchtar, MD, Morie A Gertz, MD, Betsy Laplant, MS, Francis K. Buadi, MB, CHB, Nelson Leung, MD, Stephanie M. Peterson, P. Leif Bergsagel, MD, Amie Fonder, PA-C, MS, Yi L. Hwa, NP, Miriam A. Hobbs, APRN, CNP, DNP, Dania Kaehlyn Helgeson, Alanna M. Vossen, Wilson I Gonsalves, MD, Martha Q. Lacy, MD, Prashant Kapoor, MD, Mustaqeem A. Siddiqui, MDMBA, Jeremy Larsen, Rahma M Warsame, MD, Suzanne R. Hayman, MD, Ronald S. Go, MD, David Dingli, MD PhD, Taxiarchis Kourelis, MD, Angela Dispenzieri, MD, S. Vincent Rajkumar, MD, Shaji K. Kumar, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 52–53.
https://doi.org/10.1182/blood-2020-138814
Published: 2020
Journal Articles

Heterogeneity of MYC Abnormalities in Multiple Myeloma

Neeraj Sharma, PhD, James B Smadbeck, PhD, Nadine Abdallah, MD, Kathryn E. Pearce, MS, Yan Asmann, PhD, Jess Peterson, MD, Rhett P. Ketterling, MD, Patricia Greipp, DO, P. Leif Bergsagel, MD, S. Vincent Rajkumar, MD, Shaji K. Kumar, MD, Linda B Baughn, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 2–3.
https://doi.org/10.1182/blood-2020-140844
Published: 2020
Journal Articles

A Phase I Dose Escalation Study of PT-112 in Patients with Relapsed or Refractory Multiple Myeloma

Taxiarchis Kourelis, MD, Sikander Ailawadhi, Dan T. Vogl, MD, Dennis Cooper, MD, Tyler D Ames, PhD, Christina Y Yim, PhD, Matthew R Price, Jose J Jimeno, MD PhD, P. Leif Bergsagel, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 9–10.
https://doi.org/10.1182/blood-2020-134916
Published: 2020
Journal Articles

Improving the Definition of Response Assessment: Prognostic Value of Minimal Residual Disease Combined with PET/CT at Day 100 Post Autologous Stem Cell Transplantation in Multiple Myeloma

Miguel Gonzalez-Velez, MD, Mariano Arribas, Heidi E. Kosiorek, MS, Richard Butterfield, III, Carlo Guerrero, MD, Luke Mountjoy, DO, Jeremy Larsen, Craig B. Reeder, MD, P. Leif Bergsagel, MD, A. Keith Stewart, MB, ChB, Rafael Fonseca, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-142845
Published: 2020
Journal Articles

Integrative Analysis of FISH, Transcriptomics and Mutational Status Predicts Responsiveness to Novel Agents in Multiple Myeloma

Cecilia Bonolo De Campos, PhD, Caleb K Stein, PhD, Nathalie Meurice, PhD, Laura Ann Bruins, BS, Joachim L Petit, PhD, Alysia N Polito, BS, Gregory J Ahmann, BS, Shulan Tian, MS, PhD, P. Leif Bergsagel, MD, Esteban Braggio, PhD, A. Keith Stewart, MB, ChB
Journal: Blood
Blood (2019) 134 (Supplement_1): 574.
https://doi.org/10.1182/blood-2019-130977
Published: 2019
Journal Articles

Myeloma Cells Addicted to Glutamine for Biomass Production Are Sensitive to Lenalidomide

Sinto Chirackal, PhD, Esteban Braggio, PhD, Rahman Atiqur, PhD, Gregory J Ahmann, BS, Yuan Xiao Zhu, PhD, A. Keith Stewart, MB, ChB, Marta Chesi, PhD, P. Leif Bergsagel, MD, Rafael Fonseca, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4410.
https://doi.org/10.1182/blood-2019-124967
Published: 2019
Journal Articles

Aneuploidy Is Associated with Inferior Survival in Relapsed Refractory Multiple Myeloma Patients

J Christine Ye, MDMSc, Liying Chen, Jason Chen, MD, Brian Parkin, Avery Polk, Malathi Kandarpa, PhD, Craig E. Cole, MD, Erica L. Campagnaro, MD, Dan Robinson, PhD, Yi-Mi Wu, Moshe Talpaz, MD, Jennifer Yesil, Daniel Auclair, P. Leif Bergsagel, MD, Arul Chinnaiyan, MD, Veerabhadran Baladandayuthapani
Journal: Blood
Blood (2019) 134 (Supplement_1): 4360.
https://doi.org/10.1182/blood-2019-124135
Published: 2019
Journal Articles

The CCND1 870G Risk Allele Is Enriched in African Individuals with Plasma Cell Dyscrasias

Linda B Baughn, PhD, Zhou Li, MS, Kathryn E. Pearce, Celine M. Vachon, PhD, Mei-Yin Polley, PhD, Jonathan J Keats, PhD, Eran Elhaik, PhD, Michael L. Baird, PhD, Terry Therneau, PhD, James R. Cerhan, MD PhD, P. Leif Bergsagel, MD, Angela Dispenzieri, MD, S.Vincent Rajkumar, MD, Yan Asmann, PhD, Shaji K. Kumar, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4362.
https://doi.org/10.1182/blood-2019-124979
Published: 2019
Journal Articles

Altered Iron Metabolism Is a New Targetable Hallmark for Multiple Myeloma

Can Li, MD, Xuelian Tan, Qierra Brockman, BA, Yogesh Jethava, MBBS,MDFRCPath,MRCP, Marta Chesi, PhD, P. Leif Bergsagel, MD, Fangping Chen, MD PhD, Ivana Frech, DSc, PhD MBA, Fenghuang Zhan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3059.
https://doi.org/10.1182/blood-2019-123473
Published: 2019
Journal Articles

Gene Expression Profiling of Structural and Functional High-Risk Multiple Myeloma

Moritz Binder, MDMPH, S. Vincent Rajkumar, MD, Martha Q. Lacy, MD, Jessica L. Haug, Angela Dispenzieri, MD, Kimberly J. Henderson, Teresa K. Kimlinger, A. Keith Stewart, MB, ChB, P. Leif Bergsagel, MD, Shaji K. Kumar, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3061.
https://doi.org/10.1182/blood-2019-124637
Published: 2019
Journal Articles

A Novel Approach to Risk Stratification in Multiple Myeloma Using ISS Stage and FISH

Shaji K. Kumar, MD, Patricia Greipp, DO, Morie A Gertz, MD, Angela Dispenzieri, MD, Linda B Baughn, PhD, Martha Q. Lacy, MD, Suzanne R. Hayman, MD, Francis K. Buadi, MB, CHB, David Dingli, MD PhD, Prashant Kapoor, MD, Ronald S. Go, MD, Yi L. Hwa, APRN, CNP, DNP, Amie Fonder, PA-C, MS, Miriam A. Hobbs, APRN, CNP, DNP, Yi Lin, MD PhD, Nelson Leung, MD, Taxiarchis Kourelis, MD, Rahma M Warsame, MD, Mustaqeem Siddiqui, MD, John A. Lust, MD PhD, Robert A. Kyle, MD, Rhett P. Ketterling, MD, S.Vincent Rajkumar, MD, P. Leif Bergsagel, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1800.
https://doi.org/10.1182/blood-2019-130639
Published: 2019
Journal Articles

Phase 2 Trial of Ixazomib, Cyclophosphamide and Dexamethasone in Relapsed Multiple Myeloma

Francis K. Buadi, MB, CHB, Martha Q. Lacy, MD, Betsy Laplant, MS, Eric Wolfe, Morie A. Gertz, MD, Sikander Ailawadhi, MD, Suzanne R. Hayman, MD, Ronald S. Go, MD, Dania Kaehlyn Helgeson, Vivek Roy, MD, Craig B. Reeder, MD, Amie Fonder, PA-C, MS, Yi L. Hwa, APRN, CNP, DNP, Miriam A. Hobbs, APRN, CNP, DNP, P. Leif Bergsagel, MD, Rafael Fonseca, MD, David Dingli, MD PhD, Wilson I Gonsalves, MD, Prashant Kapoor, MD, Asher A. Chanan-Khan, MD, Taxiarchis Kourelis, MD, Jeremy Larsen, Stephen J Russell, MD PhD, John A. Lust, MD PhD, Taimur Sher, MD, Mustaqeem A. Siddiqui, MDMBA, A. Keith Stewart, MB, ChB, Rahma M Warsame, MD, S. Vincent Rajkumar, MD, Robert A. Kyle, MD, Shaji K. Kumar, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1904.
https://doi.org/10.1182/blood-2019-131478
Published: 2019
Journal Articles

Reconstructing the Clonal and Mutational Architecture of Myeloma through Avian Leukosis Virus (ALV)-Mediated Genome Editing

Zachary Morrow, BS, Alexander Cicala, Evan Flietner, BS, Athanasios Papadas, MD, Adam Pagenkopf, BS, Zhi Wen, PhD, Adhithi Rajagopalan, BS, Poulikos Poulikakos, PhD, Natalie Scott Callander, MD, Marta Chesi, PhD, P. Leif Bergsagel, MD, Jing Zhang, PhD, Fotios Asimakopoulos, PhD MBBChir,
Journal: Blood
Blood (2018) 132 (Supplement 1): 4480.
https://doi.org/10.1182/blood-2018-99-115288
Published: 2018
Journal Articles

Genomic Abnormalities Among African Individuals with Monoclonal Gammopathies Using Calculated Ancestry

Linda B Baughn, PhD, Dirk Larson, MS, Mei-Yin Polley, PhD, Kathryn E. Pearce, Eran Elhaik, PhD, Michael L. Baird, PhD, Colin Colby, Joanne Benson, Zhou Li, MS, Yan Asmann, PhD, Terry Therneau, PhD, James R. Cerhan, MD PhD, Celine M. Vachon, PhD, A Keith Stewart, MB, ChB, P. Leif Bergsagel, MD, Angela Dispenzieri, MD, Shaji K. Kumar, MD, S. Vincent Rajkumar, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4458.
https://doi.org/10.1182/blood-2018-99-117382
Published: 2018
Journal Articles

A Single-Cell Transcriptional Analysis of Tumour Cells and the Immune Microenvironment during Disease Evolution in a Transgenic Mouse Model of Myeloma

Danielle C Croucher, MSc, Marta Chesi, PhD, Zhihua Li, Victoria Marie Garbitt, BS, Meaghen E Sharik, BS, Daniel Waller, PhD, Michael Sebag, MD PhD, P. Leif Bergsagel, MD, Trevor J. Pugh, PhD, Suzanne Trudel, MD FRCP(C)
Journal: Blood
Blood (2018) 132 (Supplement 1): 56.
https://doi.org/10.1182/blood-2018-99-118691
Published: 2018
Journal Articles

Mice Expressing MYC and Nras Q61R in Germinal Center B Cells Develop Highly Aggressive Multiple Myeloma

Adhithi Rajagopalan, BS, Zhi Wen, PhD, Quinlan Furumo, Erik A. Ranheim, MD PhD, Remington Finn, Evan Flietner, BS, Grant Yun, Yun Zhou, MS, Mei Yu, PhD, Natalie Scott Callander, MD, Marta Chesi, PhD, P. Leif Bergsagel, MD, Robert Burns, PhD, Demin Wang, PhD, Fotios Asimakopoulos, PhDMBBChir,, Jing Zhang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1006.
https://doi.org/10.1182/blood-2018-99-116757
Published: 2018
Journal Articles

MYC Translocations Identified By Sequencing Panel in Smoldering Multiple Myeloma Strongly Predict for Rapid Progression to Multiple Myeloma

Niamh Keane, MB, MRCP, Caleb K Stein, MS, Daniel Angelov, MSc,MB, Shulan Tian, David Viswanatha, MD, Shaji K Kumar, MD, Angela Dispenzieri, MD, Veronica Gonzalez De La Calle, MD, Kristine Misund, PhD, Robert A Kyle, MD, Michael E O'Dwyer, MD, Rafael Fonseca, MD, A. Keith Stewart, MBChB, MBA, Esteban Braggio, PhD, Yan Asmann, PhD, S. Vincent Rajkumar, MD, P. Leif Bergsagel, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 393.
https://doi.org/10.1182/blood.V130.Suppl_1.393.393
Published: 2017