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Niels E Franke, MD, MSc
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Journal Articles

The Novel Proteasome Inhibitor 5-Amino-8-Hydroxyquinole (5AHQ) Overcomes Bortezomib Resistance in Malignant Hematological Cell Line Models Harboring Mutations in the PSMB5 Gene.

Niels E Franke, MD, MSc, Johan van Meerloo, B.ASc, Linda Slot, MSc, Xiaoming Li, PhD, Tabitha E Wood, PhD, Katarina Vojtekova, MSc, Sue Ellen Verbrugge, MSc, Gertjan Kaspers, MD, PhD, Robert A. Batey, PhD, Aaron D. Schimmer, MD, PhD, Gerrit Jansen, PhD, Jacqueline Cloos, PhD
Journal: Blood
Blood (2009) 114 (22): 940.
https://doi.org/10.1182/blood.V114.22.940.940
Published: 2009
Journal Articles

Acquired Resistance to Bortezomib in Human RPMI-8226 Multiple Myeloma Cells: Molecular Characterization, Cross-Resistance with Other Proteasome Inhibitors but Marked Sensitization to Glucocorticoids

Niels E Franke, MD, MSc, Gertjan L Kaspers, MD, PhD, Nynke van den Berg, Ina van Zantwijk, Katarina Vojtekova, MSc, Uzma Yaqub, BSc, Serge Smeets, MSc, Bauke Ylstra, PhD, Sonja Zweegman, MD, PhD, Gerrit Jansen, PhD, Jacqueline Cloos, PhD
Journal: Blood
Blood (2008) 112 (11): 2640.
https://doi.org/10.1182/blood.V112.11.2640.2640
Published: 2008
Journal Articles

Acquisition of Mutations in the PSMB5 Gene during Chronic Exposure of Human Acute Lymphoblastic Leukemia CCRF-CEM Cells to the Proteasome Inhibitor Bortezomib

Niels E Franke, MD, MSc, Ruud Oerlemans, MSc, Ina van Zantwijk, Katarina Vojtekova, MSc, Gertjan L Kaspers, MD, PhD, Gerrit Jansen, PhD, Jacqueline Cloos, PhD
Journal: Blood
Blood (2008) 112 (11): 2642.
https://doi.org/10.1182/blood.V112.11.2642.2642
Published: 2008