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Nancy J. Zeleznik-Le, PhD
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Journal Articles

Direct Binding of BCOR, but Not CBX8, to MLL-AF9 Is Essential for MLL-AF9 Leukemia Via Regulation of the EYA1/SIX1 Gene Network

John H. Bushweller, PhD, Charles Schmidt, Nicholas Achille, Aravinda Kuntimaddi, Adam Boulton, Benjamin Leach, Shubin Zhang, Nancy J. Zeleznik-Le, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1316.
https://doi.org/10.1182/blood-2018-99-111388
Published: 2018
Journal Articles

The Mir-17-92 Cluster Contributes to MLL Leukemia through the Repression of PKNOX1, a MEIS1 Competitor

Yousaf A Mian, Nancy J. Zeleznik-Le, PhD
Journal: Blood
Blood (2014) 124 (21): 877.
https://doi.org/10.1182/blood.V124.21.877.877
Published: 2014
Journal Articles

Structural and Functional Studies Of The Intrinsically Disordered Protein AF9 In MLL-AF9 Leukemia

Aravinda Kuntimaddi, Alyson Lokken, Shubin Zhang, Jeremy Thorpe, Benjamin Leach, PhD, Bhavna Lumba, PhD, Charles S. Hemenway, MD, PhD, Mazhar Adli, PhD, Nancy J. Zeleznik-Le, PhD, John H. Bushweller, PhD
Journal: Blood
Blood (2013) 122 (21): 3762.
https://doi.org/10.1182/blood.V122.21.3762.3762
Published: 2013
Journal Articles

The Role of the Intrinsically Disordered and Multifunctional AF9 C-Terminal Domain in MLL-AF9 Leukemia,

John H. Bushweller, PhD, Benjamin Leach, Ming-jin Chang, Bhavna Lumba, Tomasz Cierpicki, PhD, Nancy J. Zeleznik-Le, PhD, Charles S. Hemenway, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 3464.
https://doi.org/10.1182/blood.V118.21.3464.3464
Published: 2011
Journal Articles

Title: Promoter Methylation of Selected Genes and Response to Azacitidine (AZ) Therapy in Patients with Non-BCR-ABL Myeloproliferative Disorders (MPDs)

Nicholas Achille, BS, Laura Michaelis, MD, Scott E. Smith, MD, PhD, FACP, Eliza Germano, Nancy J. Zeleznik-Le, PhD, Sucha Nand, MD
Journal: Blood
Blood (2011) 118 (21): 4625.
https://doi.org/10.1182/blood.V118.21.4625.4625
Published: 2011
Journal Articles

DNMT1 Cxxc Domain Can Functionally Substitute In An MLL Fusion Protein

Laurie E. Risner, PhD, Aravinda Kuntimaddi, John H. Bushweller, PhD, Nancy J. Zeleznik-Le, PhD
Journal: Blood
Blood (2010) 116 (21): 4193.
https://doi.org/10.1182/blood.V116.21.4193.4193
Published: 2010
Journal Articles

Epigenetic Signaling Is Required for HoxA9-Based Leukemic Transformation.

Aditya Chaubey, Ph.D., Chinavenmeni S. Velu, PhD, Shane Horman, PhD, Anil Jegga, Monica L. Guzman, PhD, Laurie Risner, Nancy J. Zeleznik-Le, PhD, Craig T. Jordan, PhD, Martin Carroll, MD, Brian Gebelein, Ph.D., H. Leighton Grimes, PhD
Journal: Blood
Blood (2009) 114 (22): 3966.
https://doi.org/10.1182/blood.V114.22.3966.3966
Published: 2009
Journal Articles

Structural Basis for MLL Cxxc Domain Protection against CpG DNA Methylation and the Essential Role of This Function in MLL-AF9 Leukemia.

Laurie Risner, Tomasz Cierpicki, PhD, Jolanta Grembecka, PhD, Stephen M Lukasik, PhD, Relja Popovic, PhD, David S Shultis, PhD, Nancy J. Zeleznik-Le, PhD, John H. Bushweller, PhD
Journal: Blood
Blood (2009) 114 (22): 763.
https://doi.org/10.1182/blood.V114.22.763.763
Published: 2009