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Journal Articles

Severe Adverse Events By First Line Tyrosine Kinase Inhibitors Decrease Survival Rate in Patients with Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia

Shuichi Ota, MD PhD, Toshihiro Matsukawa, MD PhD, Satoshi Yamamoto, MD, Shinichi Ito, MD, Motohiro Shindo, MD, Kazuya Sato, MD PhD, Takeshi Kondo, MD PhD, Tohru Takahashi, MD, Tsutomu Sato, MD PhD, Yasutaka Kakinoki, MD PhD, Hajime Kobayashi, MD, Mitsutoshi Kurosawa, MD PhD

Blood (2016) 128 (22): 1898.

https://doi.org/10.1182/blood.V128.22.1898.1898

Published: 2016

Journal Articles

Usefulness of Reticulocyte Hemoglobin Equivalent for Diagnosis of Iron Deficiency

Yasumichi Toki, MD PhD, Katsuya Ikuta, MD PhD, Masayo Yamamoto, MD PhD, Mayumi Hatayama, MD, Motohiro Shindo, MD PhD, Mikihiro Fujiya, MD PhD, Toshikatsu Okumura, MD PhD

Blood (2016) 128 (22): 3621.

https://doi.org/10.1182/blood.V128.22.3621.3621

Published: 2016

Journal Articles

First-Line Dasatinib Treatment of CML-CP Leads to Earlier Achievement of MMR and MR4.5 with High Safety

Blood (2016) 128 (22): 3102.

https://doi.org/10.1182/blood.V128.22.3102.3102

Published: 2016

Journal Articles

Velocity of Early BCR-ABL Transcript Elimination As an Optimized Predictor of Deep Molecular Response in Chronic Myeloid Leukemia Patients in Chronic Phase on Treatment with Dasatinib

Kazunori Murai, MD PhD, Kohei Yamaguchi, MD, Shigeki Ito, MD PhD, Tomoaki Akagi, Kazuei Ogawa, MD PhD, Inomata Mitsue, Kuniaki Meguro, Reiko Watanabe, MD PhD, Takuto Miyagishima, MD, PhD, Kentaro Wakasa, Motohiro Shindo, MD PhD, Yasuhiko Tsukushi, MD PhD, Kohmei Kubo, MD, PhD, Koji Oba, PhD, Junichi Sakamoto, MDPhD, Yoji Ishida, MD, PhD

Blood (2015) 126 (23): 4052.

https://doi.org/10.1182/blood.V126.23.4052.4052

Published: 2015

Journal Articles

Functional Validation and Clinical Significance Of a Newly Established Non-Transferrin-Bound Iron (NTBI) Assay System Utilizing Conventional Automated Analyzer

Satoshi Ito, MD, Katsuya Ikuta, MD, PhD, Lynda Addo, Mayumi Hatayama, MD, Yasumichi Toki, MD, Hiroki Tanaka, PhD, Junki Inamura, MD, PhD, Motohiro Shindo, M.D., Ph.D., Yoshihiro Torimoto, MD, PhD, Yutaka Kohgo, MD, PhD

Blood (2013) 122 (21): 960.

https://doi.org/10.1182/blood.V122.21.960.960

Published: 2013

Journal Articles

Pharmacokinetic (PK) and Pharmacodynamic (PD) Study Of Dasatinib In Chronic Phase Of Newly Diagnosed Chronic Myeloid Leukemia (CML-CP)

Blood (2013) 122 (21): 4031.

https://doi.org/10.1182/blood.V122.21.4031.4031

Published: 2013

Journal Articles

Clinical Efficacy and Safety Of Dasatinib For Newly Diagnosed Chronic Myeloid Leukemia In Chronic Phase In Japan

Kohei Yamaguchi, M.D., Kazunori Murai, M.D., Ph.D., Shigeki Ito, M.D., Ph.D., Tomoaki Akagi, M.D., Ph.D., Kazuei Ogawa, M.D., Ph.D., Kuniaki Meguro, M.D., Ph.D., Mitsue Inomata, M.D., Reiko Watanabe, M.D., Ph.D., Takuto Miyagishima, M.D., Kentaro Wakasa, M.D., Motohiro Shindo, M.D., Ph.D., Yasuhiko Tsukushi, M.D., Kohmei Kubo, M.D., Ph.D., Yoji Ishida, M.D., Ph.D.

Blood (2013) 122 (21): 1493.

https://doi.org/10.1182/blood.V122.21.1493.1493

Published: 2013

Journal Articles

Increased Expression Of NGF In Hepatocytes Is An Early Event In Iron Overloaded Mouse By Transcriptome Analysis

Masayo Yamamoto, MD, Hiroki Tanaka, PhD, Lynda Addo, Satoshi Ito, MD, Motohiro Shindo, M.D., Ph.D., Katsuya Ikuta, MD, PhD, Katsunori Sasaki, PHD, Takaaki Ohtake, MD, PHD, Mikihiro Fujiya, MD, PHD, Yoshihiro Torimoto, MD, PhD, Yutaka Kohgo, MD, PhD

Blood (2013) 122 (21): 2194.

https://doi.org/10.1182/blood.V122.21.2194.2194

Published: 2013

Journal Articles

Anti-Proliferative Effect of Itraconazole On ALCL-Derived Cell Line

Naoka Okamura, MD, Katsuya Ikuta, MD, PhD, Hiroki Tanaka, PhD, Lynda Addo, Yasumichi Toki, MD, Satoshi Ito, MD, Motohiro Shindo, MD, PhD, Kazuya Sato, MD, PhD, Yoshihiro Torimoto, MD, PhD, Yutaka Kohgo, MD, PhD

Blood (2012) 120 (21): 1367.

https://doi.org/10.1182/blood.V120.21.1367.1367

Published: 2012

Journal Articles

Nobel Non-Transferrin-Bound Iron (NTBI) Measuring System Utilizing Automatic Analyzer

Satoshi Ito, MD, Katsuya Ikuta, MD, PhD, Katsunori Sasaki, PhD, Motohiro Shindo, MD, PhD, Yoshihiro Torimoto, MD, PhD, Yutaka Kohgo, MD, PhD

Blood (2012) 120 (21): 3207.

https://doi.org/10.1182/blood.V120.21.3207.3207

Published: 2012

Journal Articles

Role of Allogeneic Stem Cell Transplantation for Adult T-Cell Leukemia in an HTLV-1 Non-Endemic Area of Japan.

Akio Shigematsu, MD, PhD, Junji Tanaka, MD, PhD, Naoki Kobayashi, MD, PhD, Hiroshi Yasui, MD, PhD, Motohiro Shindo, MD, PhD, Yasutaka Kakinoki, MD, PhD, Kakinoki Yasutaka, MD, PhD, Satoshi Iyama, MD, PhD, Kuroda HIroyuki, MD, PhD, Tsutsumi Yutaka, MD.PhD, Satoshi Hashino, MD, PhD, Masahiro Imamura, MD, PhD, Takanori Teshima, MD, PhD

Blood (2012) 120 (21): 3089.

https://doi.org/10.1182/blood.V120.21.3089.3089

Published: 2012

Journal Articles

Direct Upregulation of Iron Regulatory Hormone Hepcidin by Interferon Alpha

Kazuhiko Ichiki, MD, Katsuya Ikuta, MD, PhD, Hiroki Tanaka, PhD, Yusuke Sasaki, Yasushi Shimonaka, Katsunori Sasaki, PhD, Satoshi Ito, MD, Motohiro Shindo, MD, PhD, Takaaki Ohtake, MD, PhD, Yoshihiro Torimoto, MD, PhD, Yutaka Kohgo, MD, PhD

Blood (2011) 118 (21): 2103.

https://doi.org/10.1182/blood.V118.21.2103.2103

Published: 2011

Journal Articles

A Crucial Cytotoxic Role of Anti-Idiotypic Antibody in Immunotherapy for B-Cell Neoplasms with Tumor Cell-Derived Heat Shock Protein 70.

Kazuya Sato, MD., PhD, Junko Jimbo, MD, PhD, Naoka Okamura, MD., Takaaki Hosoki, MD, PhD, Motohiro Shindo, MD, PhD, Katsuya Ikuta, MD, PhD, Yusuke Mizukami, MD, PhD, Mikihiro Fujiya, MD., PhD, Yoshihiro Torimoto, MD, PhD, Yutaka Kohgo, MD., PhD

Blood (2009) 114 (22): 1642.

https://doi.org/10.1182/blood.V114.22.1642.1642

Published: 2009

Journal Articles

Characterization of the Interaction Between Diferric Transferrin and Transferrin Receptor 2 by Functional Assays and Atomic Force Microscopy (AFM).

Katsuya Ikuta, MD, PhD, Alexandre Yersin, PhD, Junko Jimbo, MD, PhD, Takaaki Hosoki, MD, Motohiro Shindo, MD, PhD, Kazuya Sato, MD, PhD, Yoshihiro Torimoto, MD, PhD, Atsushi Ikai, PhD, Yutaka Kohgo, MD, PhD

Blood (2008) 112 (11): 1853.

https://doi.org/10.1182/blood.V112.11.1853.1853

Published: 2008

Journal Articles

Changes of the Expressions of the Genes Involved in Iron Metabolism by the Iron Chelation Therapy in the Iron Overloaded Mouse Model.

Katsuya Ikuta, MD, PhD, Yoshihiro Torimoto, MD, PhD, Takaaki Hosoki, MD, Junko Jimbo, MD, PhD, Motohiro Shindo, MD, PhD, Kazuya Sato, MD, PhD, Takaaki Ohtake, MD, PhD, Katsunori Sasaki, PhD, Yutaka Kohgo, MD, PhD

Blood (2008) 112 (11): 1854.

https://doi.org/10.1182/blood.V112.11.1854.1854

Published: 2008

Journal Articles

Intracellular Recycling and Iron Donating Ability of Transferrin Receptor 2α Protein Expressed in Transferrin Receptor-Deficient Chinese Hamster Ovary Cells.

Katsuya Ikuta, MD, PhD, Junko Jimbo, M.D., Takaaki Hosoki, M.D., Motohiro Shindo, M.D., Ph.D., Kazuya Sato, M.D., Ph.D., Yoshihiro Torimoto, M.D., Ph.D., Yutaka Kohgo, M.D., Ph.D.

Blood (2007) 110 (11): 2671.

https://doi.org/10.1182/blood.V110.11.2671.2671

Published: 2007

Journal Articles

A Novel Cytotoxic Mechanism by Leukemia-Specific Antibody in Immunotherapy with Leukemia Cell-Derived Heat Shock Protein 70.

Kazuya Sato, MD, PhD, Junko Jimbo, MD, Takaaki Hosoki, MD, Motohiro Shindo, MD, PHD, Katsuya Ikuta, MD, PHD, Yoshihiro Torimoto, MD, PHD, Yutaka Kohgo, MD, PHD

Blood (2007) 110 (11): 2302.

https://doi.org/10.1182/blood.V110.11.2302.2302

Published: 2007

Journal Articles

Leukemia Specific Humoral Immune Responses in Immunotherapy with Leukemia Cell-Derived HSP70 in Mice.

Junko Jimbo, MD, Kazuya Sato, MD/PhD, Takaaki Hosoki, MD, Motohiro Shindo, MD/PhD, Katsuya Ikuta, MD/PhD, Yoshihiro Torimoto, MD/PhD, Yutaka Kohgo, MD/PhD

Blood (2006) 108 (11): 5192.

https://doi.org/10.1182/blood.V108.11.5192.5192

Published: 2006

Journal Articles

Leukemia Specific Complement Dependent Cytotoxicity Contributes to Anti-Leukemia Immunity Induced by Leukemia Cell-Derived HSP70 Immunization in Mice.

Junko Jimbo, MD, Kazuya Sato, MD, PhD, Takaaki Hosoki, MD, Motohiro Shindo, MD, PhD, Katsuya Ikuta, MD, PhD, Yoshihiro Torimoto, MD, PhD, Yutaka Kohgo, MD, PhD

Blood (2005) 106 (11): 3910.

https://doi.org/10.1182/blood.V106.11.3910.3910

Published: 2005

Journal Articles

Inflammatory Cytokine IL-1β Upregulates Hepcidin Expression in Human Hepatoma Cell Lines.

Katsuya Ikuta, MD, PhD, Junki Inamura, MD, PhD, Junko Jimbo, MD, Takaaki Hosoki, MD, Motohiro Shindo, MD, PhD, Kazuya Sato, MD, PhD, Yoshihiro Torimoto, MD, PhD, Yutaka Kohgo, MD, PhD

Blood (2005) 106 (11): 3593.

https://doi.org/10.1182/blood.V106.11.3593.3593

Published: 2005

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Severe Adverse Events By First Line Tyrosine Kinase Inhibitors Decrease Survival Rate in Patients with Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia

Usefulness of Reticulocyte Hemoglobin Equivalent for Diagnosis of Iron Deficiency

First-Line Dasatinib Treatment of CML-CP Leads to Earlier Achievement of MMR and MR4.5 with High Safety

Velocity of Early BCR-ABL Transcript Elimination As an Optimized Predictor of Deep Molecular Response in Chronic Myeloid Leukemia Patients in Chronic Phase on Treatment with Dasatinib

Functional Validation and Clinical Significance Of a Newly Established Non-Transferrin-Bound Iron (NTBI) Assay System Utilizing Conventional Automated Analyzer

Pharmacokinetic (PK) and Pharmacodynamic (PD) Study Of Dasatinib In Chronic Phase Of Newly Diagnosed Chronic Myeloid Leukemia (CML-CP)

Clinical Efficacy and Safety Of Dasatinib For Newly Diagnosed Chronic Myeloid Leukemia In Chronic Phase In Japan

Increased Expression Of NGF In Hepatocytes Is An Early Event In Iron Overloaded Mouse By Transcriptome Analysis

Anti-Proliferative Effect of Itraconazole On ALCL-Derived Cell Line

Nobel Non-Transferrin-Bound Iron (NTBI) Measuring System Utilizing Automatic Analyzer

Role of Allogeneic Stem Cell Transplantation for Adult T-Cell Leukemia in an HTLV-1 Non-Endemic Area of Japan.

Direct Upregulation of Iron Regulatory Hormone Hepcidin by Interferon Alpha

A Crucial Cytotoxic Role of Anti-Idiotypic Antibody in Immunotherapy for B-Cell Neoplasms with Tumor Cell-Derived Heat Shock Protein 70.

Characterization of the Interaction Between Diferric Transferrin and Transferrin Receptor 2 by Functional Assays and Atomic Force Microscopy (AFM).

Changes of the Expressions of the Genes Involved in Iron Metabolism by the Iron Chelation Therapy in the Iron Overloaded Mouse Model.

Intracellular Recycling and Iron Donating Ability of Transferrin Receptor 2α Protein Expressed in Transferrin Receptor-Deficient Chinese Hamster Ovary Cells.

A Novel Cytotoxic Mechanism by Leukemia-Specific Antibody in Immunotherapy with Leukemia Cell-Derived Heat Shock Protein 70.

Leukemia Specific Humoral Immune Responses in Immunotherapy with Leukemia Cell-Derived HSP70 in Mice.

Leukemia Specific Complement Dependent Cytotoxicity Contributes to Anti-Leukemia Immunity Induced by Leukemia Cell-Derived HSP70 Immunization in Mice.

Inflammatory Cytokine IL-1β Upregulates Hepcidin Expression in Human Hepatoma Cell Lines.

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