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Michael Topper, BS
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Journal Articles

DNA Methyltransferase Inhibitors Promote Homologous Recombination Deficiency through Induction of Immune Signaling, Sensitizing Acute Myeloid Leukemia Cells to PARP Inhibitors

Aksinija A Kogan, BS, MS, Lena J Mclaughlin, BS, Maria R. Baer, MD, Stephen Baylin, MD, Michael Topper, BS, Feyruz V. Rassool, BSc, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3763.
https://doi.org/10.1182/blood-2019-129535
Published: 2019
Journal Articles

The Combination of PARP Inhibitors and DNMT Inhibitors Modulates Immune Activity and Suggests a Role for Immune Therapy in AML

Aksinija A Kogan, BS, MS, Michael Topper, BS, Susannah C Shissler, BS, Michael S Lee, BS, Dominique R Bollino, BS, Eun Yong Choi, Rena G Lapidus, PhD, Li Li, MD PhD, Donald Small, MD PhD, Maria R. Baer, MD, Tonya J Webb, PhD, Stephen Baylin, MD, Feyruz V. Rassool, BSc, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3886.
https://doi.org/10.1182/blood-2018-99-117294
Published: 2018
Journal Articles

DNA Demethylating Agents Generate a Brcaness Effect in Multiple Sporadic Tumor Types: Prediction for Sensitivity to PARP Inhibitors in AML

Aksinija A Kogan, BS, MS, Lena J Mclaughlin, BS, Michael Topper, BS, Nidal Muvarak, PhD, Lora Stojanovic, BS, T Michael Creed, BS, MS, Soren Bentzen, PhD DMSc, Curt I. Civin, MD, Maria R. Baer, MD, Tami J Kingsbury, PhD, Stephen Baylin, MD, Feyruz V. Rassool, BSc, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3347.
https://doi.org/10.1182/blood.V130.Suppl_1.3347.3347
Published: 2017