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Michael J Humphries, PhD
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Journal Articles

Filanesib (ARRY-520) Demonstrates Potent and Rapid Activity in Preclinical Models of MM, Dependent on Bcl-2 Family Expression, and Synergistic with Dexamethasone and IMiDs

Susana Hernández-García, Laura San-Segundo, Lorena González-Méndez, Teresa Paíno, PhD, Ana Alicia López-Iglesias, MD, Montserrat Martín-Sánchez, Mercedes Garayoa, PhD BS, Michael J Humphries, PhD, Brian Tunquist, PhD BS, Maria-Victoria Mateos, Enrique M Ocio, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4710.
https://doi.org/10.1182/blood.V124.21.4710.4710
Published: 2014
Journal Articles

Efficacy of Dual Inhibition of p38 Mitogen Activated Protein Kinase (MAPK) and Tie-2 Kinase in Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Lohith Shakaladevanapura Bachegowda, MDMRCP(UK), Ioannis Mantzaris, MD, Kerry A. Morrone, MD, Nandini Keshkar, Weijuan Li, MD PhD, George Nwankwo, Samira Shahnaz, MD, Tushar D. Bhagat, PhD, Orsolya Giricz, PhD, Sanchari Bhattacharrya, PhD, Yiting Yu, PhD, Carolina D. Schinke, MD, Aby Pynadath, MD, Andrea Pellagatti, PhD, Jacqueline Boultwood, PhD, Michael J Humphries, PhD, Shannon L Winski, PhD, Matthias Bartenstein, MD, Chandan Guha, MD PhD, Leonidas Platanias, MD PhD, Ulrich Steidl, MD PhD, Amit Verma, MD
Journal: Blood
Blood (2014) 124 (21): 4628.
https://doi.org/10.1182/blood.V124.21.4628.4628
Published: 2014
Journal Articles

ARRY-520 Combined With Pomalidomide Displays Enhanced Anti-Tumor Activity In Preclinical Models Of Multiple Myeloma

Michael J Humphries, PhD, Deborah Anderson, Lance Williams, Rob Rieger, Brian Tunquist, PhD, Duncan Walker, PhD
Journal: Blood
Blood (2013) 122 (21): 3167.
https://doi.org/10.1182/blood.V122.21.3167.3167
Published: 2013