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Journal Articles

A Novel Approach for Treatment of T-Cell Malignancies: Targeting T-Cell Receptor Vβ Families

Jie Wang, MDMS, Katarzyna Urbanska, PhD, Prannda Sharma, Mathilde Poussin, Reza Nejati, MD, Lauren Shaw, Megan S. Lim, MD PhD, Stephen J. Schuster, MD, Daniel Powell, Jr., PhD

Blood (2020) 136 (Supplement 1): 28–29.

https://doi.org/10.1182/blood-2020-142010

Published: 2020

Journal Articles

Epigenetic Modulation of CD48 By NPM-ALK Promotes Immune Evasion in ALK+ ALCL

Rui Wu, MD PhD, Elena Ivan, MD, Anagh Anant Sahasrabuddhe, PhDMSc,BSc, Timothy Shaw, PhD, Charles G. Mullighan, MBBS, MD, Vasiliki Leventaki, Kojo S. J. Elenitoba-Johnson, MD, Megan S. Lim, MD PhD

Blood (2019) 134 (Supplement_1): 1510.

https://doi.org/10.1182/blood-2019-127453

Published: 2019

Journal Articles

Natural History Study of Idiopathic Multicentric Castleman Disease Identifies Effective Treatments for a Large Proportion of Patients but Treatment-Refractory Patients Remain

Blood (2019) 134 (Supplement_1): 1540.

https://doi.org/10.1182/blood-2019-131367

Published: 2019

Journal Articles

Hypercytokine-Producing Cells and Oligoclonal T-Cell Populations in Lymph Nodes from Castleman Disease Patients

Anna Wing, Wenzhao Meng, PhD, Gerald Wertheim, MD, PhD, Dale Frank, MD, Michele Paessler, D.O., Megan S. Lim, MD, PhD, Eline T. Luning Prak, MD, PhD, David C Fajgenbaum, MD MBA, MSc, Vinodh Pillai, MD, PhD

Blood (2018) 132 (Supplement 1): 3725.

https://doi.org/10.1182/blood-2018-99-116487

Published: 2018

Journal Articles

Epiproteomic Landscape and Histone Code of Cutaneous T-Cell Lymphoma/Sézary Syndrome

Ozlem Onder, PhD MSc, Rui Wu, MDPhD, Maria Wysocka, PhD, Paul L. Haun, MD, Ellen Kim, MD, Benjamin A Garcia, PhD, David Bahler, MD, Alain Rook, MD, Megan S. Lim, MD,PhD, Kojo S.J. Elenitoba-Johnson, MD

Blood (2018) 132 (Supplement 1): 780.

https://doi.org/10.1182/blood-2018-99-115347

Published: 2018

Journal Articles

Children's Oncology Group (COG) AALL0434: Successful Disease Control without Cranial Radiation in Newly Diagnosed T Lymphoblastic Lymphoma (T-LL)

Robert James Hayashi, Stuart S. Winter, MD, Kimberly P. Dunsmore, MD, Meenakshi Devidas, PhD, Brent Wood, MD PhD, Michelle L. Hermiston, MD PhD, David T Teachey, MD, Sherrie L. Perkins, MD PhD, Rodney R. Miles, MD PhD, Elizabeth A. Raetz, MD, Mignon L. Loh, MD, Naomi Winick, MD, William L. Carroll, MD, Stephen P. Hunger, MD, Megan S. Lim, MD,PhD, Catherine M. Bollard, MD, Thomas G. Gross, MD PhD

Blood (2018) 132 (Supplement 1): 1000.

https://doi.org/10.1182/blood-2018-99-113481

Published: 2018

Journal Articles

Primary Mediastinal B-Cell Lymphoma: Evaluation of Clinicopathologic Diagnosis Compared to Gene Expression Based Diagnosis in a Clinical Trial with CD30+ B-Cell Lymphomas

Jakub Svoboda, MD, Steven M. Bair, MD, Christian Steidl, MD, Marco Ruella, MD, Daniel J. Landsburg, MD, Sunita Dwivedy Nasta, MD, Stefan Klaus Barta, MD MRCP, MS, M. Reza Nejati, MD, James Nathan Gerson, MD, Lauren Elizabeth Strelec, BA, Matthew R. Youngman, BS, Elise A. Chong, MD, Olga Kutovaya, PhD, Stacy Hung, Agata M. Bogusz, MD PhD, Megan S. Lim, MD, PhD, Stephen J. Schuster, MD

Blood (2018) 132 (Supplement 1): 2959.

https://doi.org/10.1182/blood-2018-99-115024

Published: 2018

Journal Articles

N-Glycoproteomic Landscape of Human Lymphoid Cancers Reveals Novel Biomarkers and Potential Therapeutic Targets

Delphine CM Rolland, Pharm D, PhD, Venkatesha Basrur, PhD, Yoon Kyung Jeon, MD PhD, Carla McNeil-Schwalm, MD, Damian Fermin, PhD, Kevin Conlon, MS, Chih-Chiang Tsou, PhD, Noah A Brown, MD, Dafydd G Thomas, MD PhD, Nathanael G. Bailey, MD, Gilbert S Omenn, MD PhD, Alexey I Nesvizhskii, PhD, Megan S Lim, MD PhD, Kojo SJ Elenitoba-Johnson, MD

Blood (2015) 126 (23): 697.

https://doi.org/10.1182/blood.V126.23.697.697

Published: 2015

Journal Articles

Comparative Phosphoproteomics Study Between Obinutuzumab (GA101) Vs. Rituximab (RTX) Against RTX Sensitive/Resistant Burkitt Lymphoma (BL): Differentially Phosphorylated B Cell Receptor, Fc-Gamma Receptor, Phagocytosis and Natural Killer Cell-Mediated Cytotoxicity Signaling Pathway Proteins

Aradhana Tiwari, Delphine CM Rolland, PharmD, PhD, Mona Elmacken, MD, Janet Ayello, MS, Carmella van de Ven, MA, Venkatesha Basrur, PhD, Kevin Conlon, MS, Damine Fermin, PhD, Matthew J. Barth, MD, Christian Klein, PhD, Kojo Elenitoba-Johnson, Megan S Lim, MD PhD, Mitchell S. Cairo, MD

Blood (2015) 126 (23): 1550.

https://doi.org/10.1182/blood.V126.23.1550.1550

Published: 2015

Journal Articles

Ibrutinib Significantly Prolonged Survival in a Human Burkitt Lymphoma (BL) Xenograft NSG Mouse Model: Ibrutinib May be a Potential Adjuvant Agent in the Treatment of BL

Sanghoon Lee, PhD MSc., Changhong Yin, MD MS, Janet Ayello, MS, Erin Morris, RN, Timmy O'Connell, MS, Lauren Harrison, RN, MSN, Carmella van de Ven, MA, Matthew J. Barth, MD, Rodney R. Miles, MD PhD, Paul J. Galardy, MD, Stanton Goldman, MD, Megan S Lim, MD PhD, Michelle L. Hermiston, MD PhD, Linda McAllister-Lucas, MDPhD, Lisa Giulino-Roth, MD, Sherrie L. Perkins, MD PhD, Mitchell S. Cairo, MD

Blood (2015) 126 (23): 5117.

https://doi.org/10.1182/blood.V126.23.5117.5117

Published: 2015

Journal Articles

NPM-ALK Mediated Tyrosine Phosphorylation of ATP Citrate Lyase Regulates Lipid Metabolism and Promotes Oncogenesis of Anaplastic Large Cell Lymphoma

Johnvesly Basappa, PhD, Mahmoud A ElAzzouny, PhD, Delphine CM Rolland, Pharm D, PhD, Thirunavukkarasu Velusamy, PhD, Steven Hwang, BS, Venkatesha Basrur, PhD, Kevin Conlon, MS, Lili Zhao, PhD, Nathanael G. Bailey, MD, Charles F Burant, MDPhD, Kojo SJ Elenitoba-Johnson, MD, Megan S Lim, MD PhD

Blood (2015) 126 (23): 465.

https://doi.org/10.1182/blood.V126.23.465.465

Published: 2015

Journal Articles

Ibrutinib Alone and in Combination with Dexamethasone and Carfilzomib Significantly Inhibits Cell Proliferation in Primary Mediastinal B-Cell Lymphoma (PMBL): Ibrutinib May be a Future Targeted Agent in Combination Therapy in Patients with PMBL

Sanghoon Lee, PhD MSc., Changhong Yin, MD MS, Janet Ayello, MS, Erin Morris, RN, Lauren Harrison, RN, MSN, Carmella van de Ven, MA, Matthew J. Barth, MD, Rodney R. Miles, MD PhD, Paul J. Galardy, MD, Stanton Goldman, MD, Megan S Lim, MD PhD, Michelle L. Hermiston, MD PhD, Linda McAllister-Lucas, MDPhD, Lisa Giulino-Roth, MD, Sherrie L. Perkins, MD PhD, Mitchell S. Cairo, MD

Blood (2015) 126 (23): 4852.

https://doi.org/10.1182/blood.V126.23.4852.4852

Published: 2015

Journal Articles

PTBP1 Interacts with PKM2 in an NPM-ALK-Dependent Manner and Contributes to the Pathogenesis of Anaplastic Large Cell Lymphoma (ALCL)

Johnvesly Basappa, PhD, Steven R Hwang, BS, Scott RP McDonnell, PhD, Venkatesh Basrur, PhD, Carlos Murga-Zamalloa, MD, Kojo S.J. Elenitoba-Johnson, MD, Megan S Lim, MD PhD

Blood (2014) 124 (21): 3010.

https://doi.org/10.1182/blood.V124.21.3010.3010

Published: 2014

Journal Articles

Novel Gene Translocations Involving TYK2 in Cutaneous CD30-Positive Lymphoproliferative Disorders

Thirunavukkarasu Velusamy, PhD, Mark J. Kiel, MD PhD, Anagh A Sahasrabuddhe, PhD, Delphine C.M. Rolland, PharmD, PhD, Catherine A Dixon, PhD, Nathanael G. Bailey, MD, Bryan L Betz, PhD, Noah A. Brown, MD, Alexandra C Hristov, MD, Ryan A. Wilcox, MD PhD, Roberto N. Miranda, MD, L. Jeffrey Medeiros, MD, Yoon K Jeon, MD, Megan S Lim, MD PhD, Kojo S.J. Elenitoba-Johnson, MD

Blood (2014) 124 (21): 3032.

https://doi.org/10.1182/blood.V124.21.3032.3032

Published: 2014

Journal Articles

Integrated Genome Sequencing Reveals Frequent Loss of Function Alterations of ARID1A and Other Epigenetic Modifiers in Sezary Syndrome

Mark Kiel, MDPhD, Anagh A Sahasrabuddhe, PhD, Thiru Velusamy, PhD, Fuzon Chung, PhD, Nathanael G. Bailey, MD, Bryan L Betz, PhD, David W Bahler, MD PhD, Roberto N. Miranda, MD, L. Jeffrey Medeiros, MD, Megan S Lim, MD PhD, Kojo S.J. Elenitoba-Johnson, MD

Blood (2014) 124 (21): 706.

https://doi.org/10.1182/blood.V124.21.706.706

Published: 2014

Journal Articles

A Novel Non-Canonical Phosphodegron Regulates EZH2 Proteasomal Degradation and H3K27 Trimethylation Activity in Hematopoietic Malignancies

Anagh A Sahasrabuddhe, PhD, Xiaofei Chen, PhD, Thirunavukkarasu Velusamy, PhD, Fuzon Chung, PhD, Megan S Lim, MD PhD, Kojo S.J. Elenitoba-Johnson, MD

Blood (2014) 124 (21): 1678.

https://doi.org/10.1182/blood.V124.21.1678.1678

Published: 2014

Journal Articles

Deregulation of the PI3K/Akt Signal Transduction Pathway Is Associated with the Development of Chemotherapy Resistance and Can be Effectively Targeted to Improve Chemoresponsiveness in Burkitt Lymphoma Pre-Clinical Models

Sarah Frys, BSc, Natalie M Czuczman, BSc, Cory Mavis, BSc, MSc, Delphine C.M. Rolland, PharmD, PhD, Megan S Lim, MD PhD, Aradhana Tiwari, Mitchell S. Cairo, MD, Rodney R. Miles, MD PhD, Matthew J. Barth, MD

Blood (2014) 124 (21): 1769.

https://doi.org/10.1182/blood.V124.21.1769.1769

Published: 2014

Journal Articles

The Absolute Lymphocyte to Monocyte Ratio at Diagnosis Further Stratifies Survival Based on Cell of Origin in Diffuse Large B-Cell Lymphoma

Sumana Devata, MD, Nicholas Herrman, Robert Briski, Farahk Keyoumarsi, Daniel F Boyer, MD, Megan S Lim, MD PhD, Nathanael G. Bailey, MD, Ryan A. Wilcox, MD PhD

Blood (2014) 124 (21): 1646.

https://doi.org/10.1182/blood.V124.21.1646.1646

Published: 2014

Journal Articles

A Comparative Global Phosphoproteomics Analysis of Obinutuzumab (GA101) Versus Rituximab (RTX) Against RTX Sensitive and Resistant Burkitt Lymphoma (BL) Demonstrates Differential Phosphorylation of Signaling Pathways Proteins

Aradhana Awasthi, PhD, Delphine C.M. Rolland, PharmD, PhD, Mona Elmacken, MD, Christopher Reggio, Janet Ayello, MS, MT(ASCP), Carmella van de Ven, MA, Venkatesha Basrur, PhD, Kevin Conlon, MS, Damian Fermin, PhD, Matthew J. Barth, MD, Kojo S.J. Elenitoba-Johnson, MD, Megan S Lim, MD PhD, Mitchell S. Cairo, MD

Blood (2014) 124 (21): 5481.

https://doi.org/10.1182/blood.V124.21.5481.5481

Published: 2014

Journal Articles

SCF-β-TrCP E3 Ubiquitin Ligase-Mediated Proteolysis Of EZH2 Regulates H3K27 Trimethylation Activity In Germinal Center-Derived B-Cell Lymphomas

Anagh A Sahasrabuddhe, PhD, Xiaofei Chen, PhD, Fuzon Chung, PhD, Thirunavukkarasu Velusamy, PhD, Megan S Lim, MD, PhD, Kojo S.J. Elenitoba-Johnson, MD

Blood (2013) 122 (21): 244.

https://doi.org/10.1182/blood.V122.21.244.244

Published: 2013

NARROW

A Novel Approach for Treatment of T-Cell Malignancies: Targeting T-Cell Receptor Vβ Families

Epigenetic Modulation of CD48 By NPM-ALK Promotes Immune Evasion in ALK+ ALCL

Natural History Study of Idiopathic Multicentric Castleman Disease Identifies Effective Treatments for a Large Proportion of Patients but Treatment-Refractory Patients Remain

Hypercytokine-Producing Cells and Oligoclonal T-Cell Populations in Lymph Nodes from Castleman Disease Patients

Epiproteomic Landscape and Histone Code of Cutaneous T-Cell Lymphoma/Sézary Syndrome

Children's Oncology Group (COG) AALL0434: Successful Disease Control without Cranial Radiation in Newly Diagnosed T Lymphoblastic Lymphoma (T-LL)

Primary Mediastinal B-Cell Lymphoma: Evaluation of Clinicopathologic Diagnosis Compared to Gene Expression Based Diagnosis in a Clinical Trial with CD30+ B-Cell Lymphomas

N-Glycoproteomic Landscape of Human Lymphoid Cancers Reveals Novel Biomarkers and Potential Therapeutic Targets

Comparative Phosphoproteomics Study Between Obinutuzumab (GA101) Vs. Rituximab (RTX) Against RTX Sensitive/Resistant Burkitt Lymphoma (BL): Differentially Phosphorylated B Cell Receptor, Fc-Gamma Receptor, Phagocytosis and Natural Killer Cell-Mediated Cytotoxicity Signaling Pathway Proteins

Ibrutinib Significantly Prolonged Survival in a Human Burkitt Lymphoma (BL) Xenograft NSG Mouse Model: Ibrutinib May be a Potential Adjuvant Agent in the Treatment of BL

NPM-ALK Mediated Tyrosine Phosphorylation of ATP Citrate Lyase Regulates Lipid Metabolism and Promotes Oncogenesis of Anaplastic Large Cell Lymphoma

Ibrutinib Alone and in Combination with Dexamethasone and Carfilzomib Significantly Inhibits Cell Proliferation in Primary Mediastinal B-Cell Lymphoma (PMBL): Ibrutinib May be a Future Targeted Agent in Combination Therapy in Patients with PMBL

PTBP1 Interacts with PKM2 in an NPM-ALK-Dependent Manner and Contributes to the Pathogenesis of Anaplastic Large Cell Lymphoma (ALCL)

Novel Gene Translocations Involving TYK2 in Cutaneous CD30-Positive Lymphoproliferative Disorders

Integrated Genome Sequencing Reveals Frequent Loss of Function Alterations of ARID1A and Other Epigenetic Modifiers in Sezary Syndrome

A Novel Non-Canonical Phosphodegron Regulates EZH2 Proteasomal Degradation and H3K27 Trimethylation Activity in Hematopoietic Malignancies

Deregulation of the PI3K/Akt Signal Transduction Pathway Is Associated with the Development of Chemotherapy Resistance and Can be Effectively Targeted to Improve Chemoresponsiveness in Burkitt Lymphoma Pre-Clinical Models

The Absolute Lymphocyte to Monocyte Ratio at Diagnosis Further Stratifies Survival Based on Cell of Origin in Diffuse Large B-Cell Lymphoma

A Comparative Global Phosphoproteomics Analysis of Obinutuzumab (GA101) Versus Rituximab (RTX) Against RTX Sensitive and Resistant Burkitt Lymphoma (BL) Demonstrates Differential Phosphorylation of Signaling Pathways Proteins

SCF-β-TrCP E3 Ubiquitin Ligase-Mediated Proteolysis Of EZH2 Regulates H3K27 Trimethylation Activity In Germinal Center-Derived B-Cell Lymphomas

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American Society of Hematology

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American Society of Hematology

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