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Journal Articles

How KEAP1 Deletion in Single Cell Mitigates Sickle Cell Pathology

Nadine Keleku Lukwete, PhD, Mikiko Suzuki, PhD, Harit Panda, Akihito Otsuki, PhD, Fumiki Katsuoka, PhD, Ritsumi Saitou, MD, Daisuke Saigusa, PhD, Akira Uruno, MD PhD, Masayuki Yamamoto, MD PhD

Blood (2018) 132 (Supplement 1): 2353.

https://doi.org/10.1182/blood-2018-99-110502

Published: 2018

Journal Articles

Role of GATA2 in the Maintenance of the Bone Marrow Microenvironment

Shin Hasegawa, Tohru Fujiwara, MD PhD, Yoko Okitsu, MD PhD, Hiroki Kato, MD, PhD, Yuki Sato, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Kenichi Ishizawa, Ritsuko Shimizu, MD PhD, Masayuki Yamamoto, MD PhD, Hideo Harigae, MD

Blood (2017) 130 (Supplement 1): 3781.

https://doi.org/10.1182/blood.V130.Suppl_1.3781.3781

Published: 2017

Journal Articles

Specific Deletion of Keap1 in Endothelial Cells or/and Macrophages of SCD Mice Induces Nrf2 to Protect Tissues Against Oxidative Insults

Nadine Keleku-Lukwete, MD PhD, Panda Harit, Eriko Naganuma, Mikiko Suzuki, PhD, Masayuki Yamamoto, MD PhD

Blood (2016) 128 (22): 2475.

https://doi.org/10.1182/blood.V128.22.2475.2475

Published: 2016

Journal Articles

Keap1-Nrf2 System: Potential Role in Prevention of Sickle Cell Disease Organs Damages and Inflammation

Nadine Keleku-Lukwete, MD, Mikiko Suzuki, PhD, Akihito Otsuki, DDS, Kouhei Tsuchida, Saori Katayama, MD, Makiko Hayashi, Eriko Naganuma, Takashi Moriguchi, MDPhD, Osamu Tanabe, MDPhD, James Doug Engel, PhD, Masue Imaizumi, MDPhD, Masayuki Yamamoto, MD PhD

Blood (2015) 126 (23): 411.

https://doi.org/10.1182/blood.V126.23.411.411

Published: 2015

Journal Articles

GATA-2 Regulates Dendritic Cell Differentiation

Koichi Onodera, MD, PhD, Tohru Fujiwara, MD, PhD, Yasushi Onishi, MD, PhD, Ari Itoh-Nakadai, PhD, Yoko Okitsu, MD PhD, Noriko Fukuhara, MD PhD, Kenichi Ishizawa, MD, PhD, Ritsuko Shimizu, MD, PhD, Masayuki Yamamoto, MD, PhD, Hideo Harigae, MD, PhD

Blood (2015) 126 (23): 2382.

https://doi.org/10.1182/blood.V126.23.2382.2382

Published: 2015

Journal Articles

A Stress-Responsive Transcriptional Factor NRF2 Activates Hematopoietic Stem Cells

Murakami Shohei, PhD, Masayuki Yamamoto, MD PhD, Hozumi Motohashi, MD PhD

Blood (2015) 126 (23): 2351.

https://doi.org/10.1182/blood.V126.23.2351.2351

Published: 2015

Journal Articles

Forced HoxB4 Sustains CD45 - c-kit + Pre-Hematopoieitc Stem Cells (HSCs) Derived from Murine Induced-Pluripotent Stem Cells, Which Develop Long-Term and Short-Term Repopulating HSCs According to GATA2 Expression Level

Kiyoko Izawa, PhD, Tomoya Kakegawa, Master, Masayuki Yamamoto, MD PhD, Arinobu Tojo, MD PhD

Blood (2014) 124 (21): 1567.

https://doi.org/10.1182/blood.V124.21.1567.1567

Published: 2014

Journal Articles

Long-Term Ex Vivo Maintenance Of Murine iPSC-Derived Hematopoietic Stem/Progenitor Cells By Conditional HoxB4

Kiyoko Izawa, PhD, Masayuki Yamamoto, MD, PhD, Arinobu Tojo, MD, PhD.

Blood (2013) 122 (21): 2418.

https://doi.org/10.1182/blood.V122.21.2418.2418

Published: 2013

Journal Articles

DNA Binding Diversity Achieved Through the Interaction of GATA1 N-Finger and GATA Motif Is Important for Embryonic Erythropoiesis

Atsushi Hasegawa, Ritsuko Shimizu, MD, PhD, Hirofumi Kurokawa, PhD, Masayuki Yamamoto, MD, PhD

Blood (2012) 120 (21): 3441.

https://doi.org/10.1182/blood.V120.21.3441.3441

Published: 2012

Journal Articles

GATA1 Mutants Lacking Rb-Binding Motif Observed in Transient Abnormal Myelopoiesis in Down Syndrome

Tsutomu Toki, PhD, Eri Kobayashi, MS, Rika Kanezaki, MS, RuNan Wang, MD, Kiminori Terui, MD, PhD, Hirokazu Kanegane, MD, PhD, Miho Maeda, MD, PhD, Mikiya Endo, MD, PhD, Tatsuki Mizuochi, MD, PhD, Souichi Adachi, MD, PhD, Yasuhide Hayashi, MD, PhD, Ritsuko Shimizu, MD, PhD, Masayuki Yamamoto, MD, PhD, Etsuro Ito, MD, PhD

Blood (2011) 118 (21): 1491.

https://doi.org/10.1182/blood.V118.21.1491.1491

Published: 2011

Journal Articles

Two Distinct Transactivation Domains of GATA1 Contribute Megakaryopoiesis,

Hiroshi Kaneko, Eri Kobayashi, MS, Ritsuko Shimizu, MD, PhD, Masayuki Yamamoto, MD, PhD

Blood (2011) 118 (21): 3384.

https://doi.org/10.1182/blood.V118.21.3384.3384

Published: 2011

Journal Articles

Isolation and Characterization of Renal Erythropoietin-Producing Cells: Contribution of HIF3α In Vivo .

Xiaoqing Pan, MD, PhD, Norio Suzuki, PhD, Ikuo Hirano, Shun Yamazaki, Toshiharu Yamashita, PhD, Osamu Ohneda, MD, PhD, Naoko Minegishi, MD, PhD, Masayuki Yamamoto, MD, PhD

Blood (2010) 116 (21): 1541.

https://doi.org/10.1182/blood.V116.21.1541.1541

Published: 2010

Journal Articles

Loss of the Gata1 Gene IE Exon Leads to Variant Transcript Expression and the Production of GATA1 Protein Lacking the N-Terminal Domain.

Eri Kobayashi, Ritsuko Shimizu, Yuko Kikuchi, Satoru Takahashi, Masayuki Yamamoto, MD, PhD

Blood (2009) 114 (22): 3648.

https://doi.org/10.1182/blood.V114.22.3648.3648

Published: 2009

Journal Articles

Rescue of Erythropoietin-Deficient Mice From Anemia by Complementation with BAC Transgene.

Shun Yamazaki, Norio Suzuki, PhD, Naoshi Obara, MD, PhD, Xiaoqing Pan, MD, PhD, Ikuo Hirano, Kou-ichi Jishage, PhD, Kurisu Honda, Naoko Minegishi, MD, PhD, Masayuki Yamamoto, MD, PhD

Blood (2009) 114 (22): 3614.

https://doi.org/10.1182/blood.V114.22.3614.3614

Published: 2009

Journal Articles

Spherocytic Hemolytic Anemia Caused by Disruption of GATA1-FOG1 Interaction.

Ritsuko Shimizu, Atsushi Hasegawa, Masayuki Yamamoto, MD, PhD

Blood (2009) 114 (22): 775.

https://doi.org/10.1182/blood.V114.22.775.775

Published: 2009

Journal Articles

The Critical Function of c-Myb and CD9 On Megakaryopoiesis.

Harumi Yamamoto Mukai, MD, PhD, Tomoko Kouno, Hozumi Motohashi, Yukinori Kozuma, Hiroshi Kojima, MD, PhD, Haruhiko Ninomiya, MD, PhD, Masayuki Yamamoto, MD, PhD

Blood (2009) 114 (22): 4587.

https://doi.org/10.1182/blood.V114.22.4587.4587

Published: 2009

Journal Articles

Compound Deficiency of Nrf2 and Selenoproteins in Hematopoietic Cells Leads to Severe Defects in Erythroid and Lymphoid Lineage Development.

Yukie Kawatani, Takafumi Suzuki, Ritsuko Shimizu, Vincent Kelly, Masayuki Yamamoto, MD, PhD

Blood (2009) 114 (22): 1993.

https://doi.org/10.1182/blood.V114.22.1993.1993

Published: 2009

Journal Articles

Bidirectional Control of Transcription Factor GATA2 and Cyclin/Cdks in Hematopoietic Cells.

Naoko Minegishi, MD, PhD, Hideo Harigae, M.D., Masayuki Yamamoto, MD, PhD

Blood (2008) 112 (11): 1382.

https://doi.org/10.1182/blood.V112.11.1382.1382

Published: 2008

Journal Articles

Detection of Hypoxia-Inducible Gene Manipulation.

Shigehiko Imagawa, MD, PhD, Masaki Horie, Ken Matsumoto, Ikuo Hirano, Norio Suzuki, PhD, Masayuki Yamamoto, MD

Blood (2007) 110 (11): 3662.

https://doi.org/10.1182/blood.V110.11.3662.3662

Published: 2007

Journal Articles

Phenotypic Changes of Hematopoietic Stem Cells and Stromal Cells by Aberrant Expression of GATA−2; Possible Role for the Development of Aplastic Anemia.

Yoko Okitsu, MD, Hideo Harigae, MD, Shinichiro Takahashi, MD, Naoko Minegishi, MD, Norio Suzuki, PhD, Junichi Kameoka, MD, Masayuki Yamamoto, MD, Takeshi Sasaki, MD

Blood (2006) 108 (11): 1289.

https://doi.org/10.1182/blood.V108.11.1289.1289

Published: 2006

NARROW

How KEAP1 Deletion in Single Cell Mitigates Sickle Cell Pathology

Role of GATA2 in the Maintenance of the Bone Marrow Microenvironment

Specific Deletion of Keap1 in Endothelial Cells or/and Macrophages of SCD Mice Induces Nrf2 to Protect Tissues Against Oxidative Insults

Keap1-Nrf2 System: Potential Role in Prevention of Sickle Cell Disease Organs Damages and Inflammation

GATA-2 Regulates Dendritic Cell Differentiation

A Stress-Responsive Transcriptional Factor NRF2 Activates Hematopoietic Stem Cells

Forced HoxB4 Sustains CD45 - c-kit + Pre-Hematopoieitc Stem Cells (HSCs) Derived from Murine Induced-Pluripotent Stem Cells, Which Develop Long-Term and Short-Term Repopulating HSCs According to GATA2 Expression Level

Long-Term Ex Vivo Maintenance Of Murine iPSC-Derived Hematopoietic Stem/Progenitor Cells By Conditional HoxB4

DNA Binding Diversity Achieved Through the Interaction of GATA1 N-Finger and GATA Motif Is Important for Embryonic Erythropoiesis

GATA1 Mutants Lacking Rb-Binding Motif Observed in Transient Abnormal Myelopoiesis in Down Syndrome

Two Distinct Transactivation Domains of GATA1 Contribute Megakaryopoiesis,

Isolation and Characterization of Renal Erythropoietin-Producing Cells: Contribution of HIF3α In Vivo .

Loss of the Gata1 Gene IE Exon Leads to Variant Transcript Expression and the Production of GATA1 Protein Lacking the N-Terminal Domain.

Rescue of Erythropoietin-Deficient Mice From Anemia by Complementation with BAC Transgene.

Spherocytic Hemolytic Anemia Caused by Disruption of GATA1-FOG1 Interaction.

The Critical Function of c-Myb and CD9 On Megakaryopoiesis.

Compound Deficiency of Nrf2 and Selenoproteins in Hematopoietic Cells Leads to Severe Defects in Erythroid and Lymphoid Lineage Development.

Bidirectional Control of Transcription Factor GATA2 and Cyclin/Cdks in Hematopoietic Cells.

Detection of Hypoxia-Inducible Gene Manipulation.

Phenotypic Changes of Hematopoietic Stem Cells and Stromal Cells by Aberrant Expression of GATA−2; Possible Role for the Development of Aplastic Anemia.

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American Society of Hematology

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American Society of Hematology

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