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Masafumi Seki, MD PhD
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Journal Articles

The Prognostic Value of TP53 Mutations Depends on Clinical Backgrounds in Pediatric Patients with Acute Lymphoblastic Leukemia

Hiroo Ueno, MD, Kenichi Yoshida, MD PhD, Yusuke Shiozawa, MD, PhD, Yasuhito Nannya, MD PhD, Yuka Iijima-Yamashita, PhD, Nobutaka Kiyokawa, MD PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, PhD, Hiroko Tanaka, BA, Tomoya Isobe, MD, Masafumi Seki, MD,PhD, Shunsuke Kimura, MD, Hideki Makishima, MD PhD, Nobuyuki Kakiuchi, MD, Keisuke Kataoka, MD PhD, Tetsuichi Yoshizato, MD PhD, Hiroyuki Tsukamoto, MD PhD, Dai Nishijima, PhD, Takao Deguchi, MD PhD, Kentaro Ohki, MD PhD, Atsushi Sato, MD, Hiroyuki Takahashi, Yoshiko Hashii, MD, PhD, Sadao Tokimasa, MD, PhD, Junichi Hara, MD, PhD, Yoshiyuki Kosaka, MD PhD, Koji Kato, MD PhD, Takeshi Inukai, MD, Junko Takita, MD, PhD, Toshihiko Imamura, MD PhD, Satoru Miyano, PhD, Atsushi Manabe, MD PhD, Keizo Horibe, MD PhD, Seishi Ogawa, MD PhD, Masashi Sanada, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4077.
https://doi.org/10.1182/blood-2018-99-115617
Published: 2018
Journal Articles

Distribution and Clinical Features of NOTCH1 Signaling Activating Alterations in Pediatric T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Shunsuke Kimura, MD, Masafumi Seki, MD, PhD, Kenichi Yoshida, MD PhD, Hiroo Ueno, MD, Yasuhito Nannya, MD PhD, Kentaro Ohki, MD PhD, Motohiro Kato, MD PhD, Katsuyoshi Koh, MD, Ryoji Kobayashi, MD, Takao Deguchi, MD PhD, Yoshiko Hashii, MD PhD, Toshihiko Imamura, MD PhD, Atsushi Sato, MD, Nobutaka Kiyokawa, MD PhD, Atsushi Manabe, MD PhD, Keizo Horibe, MD PhD, Akira Ohara, MD, Masashi Sanada, MD PhD, Mitsuteru Hiwatari, MD PhD, Masao Kobayashi, MD PhD, Akira Oka, MD PhD, Satoru Miyano, PhD, Seishi Ogawa, MD PhD, Junko Takita, MD, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4089.
https://doi.org/10.1182/blood-2018-99-111092
Published: 2018
Journal Articles

Comprehensive Genomic Analysis Identified Acute Lymphoblastic Leukemia in Down Syndrome Was Highly Heterogeneous with the High Prevalence of Ph-like Signature

Yasuo Kubota, MD, Kumiko Uryu, MD PhD, Tatsuya Ito, MD, Masafumi Seki, MD,PhD, Tomoya Isobe, MD, Tsutomu Toki, PhD, Kenichi Yoshida, MD PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, PhD, Hiroko Tanaka, BA, MItsuteru Hiwatari, MD PhD, Satoru Miyano, PhD, Akira Oka, MD PhD, Seishi Ogawa, MD PhD, Kiminori Terui, MD PhD, Atsushi Sato, MD, Etsuro Ito, MD PhD, Junko Takita, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2817.
https://doi.org/10.1182/blood-2018-99-111080
Published: 2018
Journal Articles

Integrated Genetic/Epigenetic Analysis Revealed High Heterogeneity of Acute Lymphoblastic Leukemia in Down Syndrome

Yasuo Kubota, MD, Kumiko Uryu, MD PhD, Tatsuya Ito, MD, Tomoko Kawai, PhD, Masafumi Seki, MD,PhD, Tomoya Isobe, Tsutomu Toki, PhD, Kenichi Yoshida, MD PhD, Keisuke Kataoka, MD PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, B.A., Hiroko Tanaka, B.A., Satoru Miyano, PhD, Akira Oka, MD PhD, Yasuhide Hayashi, Seishi Ogawa, MD PhD, Kiminori Terui, MD PhD, Atsushi Sato, MD, Kenichiro Hata, MD PhD, Etsuro Ito, MD PhD, Junko Takita, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3975.
https://doi.org/10.1182/blood.V130.Suppl_1.3975.3975
Published: 2017
Journal Articles

Clinical Effect of Genetic Alterations in Pediatric Patients with B-Progenitor Acute Lymphoblastic Leukemia

Hiroo Ueno, MD, Kenichi Yoshida, MD PhD, Yasuhito Nannya, MD PhD, Yuka Iijima-Yamashita, M.S., Yusuke Shiozawa, MD , PhD, Yuichi Shiraishi, PhD, Tomomi Ishida, Keisuke Kataoka, MD PhD, Tetsuichi Yoshizato, MD,PhD, Hideki Makishima, MD PhD, Nobuyuki Kakiuchi, MD, Masafumi Seki, MD,PhD, Hiroko Tanaka, B.A., Kenichi Chiba, B.A., Takao Deguchi, MD PhD, Atsushi Sato, MD, Yoshiko Hashii, MD, PhD, Sadao Tokimasa, MD, PhD, Junichi Hara, MD, PhD, Yoshiyuki Kosaka, MD, PhD, Koji Kato, MD, PhD, Toshihiko Imamura, MD, PhD, Satoru Miyano, PhD, Keizo Horibe, Seishi Ogawa, MD PhD, Masashi Sanada, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3979.
https://doi.org/10.1182/blood.V130.Suppl_1.3979.3979
Published: 2017
Journal Articles

The Epigenetic and Genetic Landscapes of Pediatric T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Shunsuke Kimura, Masafumi Seki, MD,PhD, Tomoko Kawai, PhD, Kenichi Yoshida, MD PhD, Tomoya Isobe, Hiroo Ueno, MD, Yusuke Shiozawa, MD , PhD, Hiromichi Suzuki, MD , PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, B.A., Hiroko Tanaka, B.A., Kentaro Ohki, MD PhD, Motohiro Kato, MD, Katsuyoshi Koh, MD, Ryoji Hanada, MD, Ryoji Kobayashi, MD, Takao Deguchi, MD PhD, Yoshiko Hashii, MD, PhD, Toshihiko Imamura, MD, PhD, Atsushi Sato, MD, Nobutaka Kiyokawa, MD PhD, Atushi Manabe, MD PhD, Keizo Horibe, Akira Ohara, MD, Masashi Sanada, MD PhD, Masao Kobayashi, MD PhD, Akira Oka, MD PhD, Yasuhide Hayashi, MD PhD, Satoru Miyano, PhD, Kenichiro Hata, MD PhD, Seishi Ogawa, MD PhD, Junko Takita, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1444.
https://doi.org/10.1182/blood.V130.Suppl_1.1444.1444
Published: 2017
Journal Articles

RARB Translocations in Acute Promyelocytic Leukemia without Rara translocation

Motohiro Kato, MD, Tomoo Osumi, MD, Shinichi Tsujimoto, MD, Moe Tamura, Meri Uchiyama, Kazuhiko Nakabayashi, Kohji Okamura, Daisuke Tomizawa, MD PhD, Akihiro Watanabe, Hiroyuki Takahashi, Tsukasa Hori, MD PhD, Shohei Yamamoto, MD PhD, Kazuko Hamamoto, Masahiro Migita, Hiroko Ogata-Kawata, Toru Uchiyama, Hiroe Kizawa, Hitomi Ueno-Yokohata, Ryota Shirai, Masanori Yoshida, Masafumi Seki, MD,PhD, Kentaro Oki, MD PhD, Junko Takita, MD PhD, Seishi Ogawa, MD PhD, Toshio Kitamura, MD PhD, Kimikazu Matsumoto, Kenichiro Hata, MD PhD, Susumu Goyama, MD PhD, Nobutaka Kiyokawa, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 104.
https://doi.org/10.1182/blood.V130.Suppl_1.104.104
Published: 2017
Journal Articles

Identifications of Highly Aggressive Phenotype with SPI1 Overexpression in Pediatric T Cell Acute Lymphoblastic Leukemia/Lymphoma

Masafumi Seki, MD PhD, Shunsuke Kimura, MD, Kenichi Yoshida, MD PhD, Tomoya Isobe, MD, Hiroo Ueno, MD, Hiromichi Suzuki, MD PhD, Yusuke Shiozawa, MD, Keisuke Kataoka, MD PhD, Yoichi Fujii, MD, Yuichi Shiraishi, PhD, Kenichi Chiba, BA, Hiroko Tanaka, BA, Masatoshi Takagi, MD PhD, Atsushi Iwama, MD PhD, Kentaro Oki, MDPhD, Motohiro Kato, MD PhD, Katsuyoshi Koh, MD, Ryoji Hanada, MD, Hiroshi Moritake, MD PhD, Ryoji Kobayashi, MD PhD, Takao Deguchi, MD PhD, Yoshiko Hashii, MD PhD, Toshihiko Imamura, MD PhD, Atsushi Sato, MD, Keizo Horibe, MD PhD, Nobutaka Kiyokawa, MD PhD, Atsushi Manabe, MD PhD, Akira Ohara, MD PhD, Masashi Sanada, MD PhD, Yasuhide Hayashi, MD PhD, Hiroyuki Mano, MDPhD, Satoru Miyano, PhD, Akira Oka, MD PhD, Seishi Ogawa, MD PhD, Junko Takita, MD PhD
Journal: Blood
Blood (2016) 128 (22): 909.
https://doi.org/10.1182/blood.V128.22.909.909
Published: 2016
Journal Articles

TAL1 Super Enhancer Aberration and Stil-TAL1 Fusion in Pediatric T Cell Acute Lymphoblastic Leukemia

Shunsuke Kimura, MD, Masafumi Seki, MD PhD, Kenichi Yoshida, MD PhD, Hiroo Ueno, MD, Yuichi Shiraishi, PhD, Kenichi Chiba, BA, Hiroko Tanaka, BA, Hiromichi Suzuki, MD PhD, Keisuke Kataoka, MD PhD, Kentaro Ohki, MD PhD, Motohiro Kato, MD PhD, Katsuyoshi Koh, MD, Ryoji Hanada, MD, Nobutaka Kiyokawa, MD PhD, Masao Kobayashi, MD PhD, Atsushi Manabe, MD PhD, Akira Ohara, MD PhD, Yasuhide Hayashi, MD PhD, Satoru Miyano, PhD, Seishi Ogawa, MD PhD, Junko Takita, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1734.
https://doi.org/10.1182/blood.V128.22.1734.1734
Published: 2016
Journal Articles

Gene Expression Profiles and Methylation Analysis in Down Syndrome Related Acute Lymphoblastic Leukemia

Yasuo Kubota, MD, Kumiko Uryu, MD, Tomoko Kawai, Tatsuya Ito, MD, Isamu Hanada, MD PhD, Tsutomu Toki, PhD, Masafumi Seki, MD PhD, Kenichi Yoshida, MD PhD, Keisuke Kataoka, MD PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, BA, Hiroko Tanaka, BA, Satoru Miyano, PhD, Akira Oka, MD PhD, Yasuhide Hayashi, MD PhD, Seishi Ogawa, MD PhD, Kiminori Terui, MD PhD, Atsushi Sato, MD PhD, Kenichiro Hata, Etsuro Ito, MD PhD, Junko Takita, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4084.
https://doi.org/10.1182/blood.V128.22.4084.4084
Published: 2016