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Journal Articles

A Deptor Inhibitor Induces Its Degradation with Resulting Anti-Myeloma Cytotoxicity in Vitro and In Vivo

Mario I Vega, PhD, Yijiang Shi, MD PhD, Patrick Frost, PhD, Sara Huerta-Yepez, PhD, Alan Lichtenstein, MD

Blood (2019) 134 (Supplement_1): 1821.

https://doi.org/10.1182/blood-2019-121480

Published: 2019

Journal Articles

Role of the microRNA-7 (miR-7) in the Inhibition of Chemoresistance and Migration of Lymphoma Non-Hodgkin's through Regulation of YY1 and KLF4

Mario Morales-Martinez, PhDSt, Gabriel G Vega, PhD, Natividad Neri Munoz, PhD MD, M. J Nambo, Isabel Alvarado, Ivonne Cuadra, MD, M. A. Duran-Padilla, MD, Sara Huerta-Yepez, PhD, Mario I Vega, PhD

Blood (2019) 134 (Supplement_1): 5220.

https://doi.org/10.1182/blood-2019-121469

Published: 2019

Journal Articles

Fusion Protein Ompc-CD154 Inhibits Proliferation and Induces Apoptosis in B-NHL Cell Lines By a Mechanism That Involves MAPK P38 and TRAF2 Activation

Gerardo Pantoja-Escobar, PhD, Laura Romo-Dorantes, Mario Morales-Martinez, PhD Student, Gabriel G Vega, PhD student, Otoniel Martinez-Maza, PhD, Sara Huerta-Yepez, PhD, Mario I. Vega, PhD

Blood (2016) 128 (22): 5306.

https://doi.org/10.1182/blood.V128.22.5306.5306

Published: 2016

Journal Articles

KLF4 and YY1 Are Resistant Factors in NHL and Potential Therapeutic Targets: The New Resistant NF-κb/YY1/KLF4/Bcl xL /Mcl-1 Axis

Mayra R Montecillo-Aguado, MsC, Gabriel G Vega, PhDstudent, Hector Mayani, PhD, Sara Huerta-Yepez, PhD, Benjamin Bonavida, PhD, Otoniel Martinez-Maza, PhD, Mario I. Vega, PhD

Blood (2015) 126 (23): 1466.

https://doi.org/10.1182/blood.V126.23.1466.1466

Published: 2015

Journal Articles

Cooperation Between the CD20 Receptor and hIFN-Alpha Receptor in Overriding the Blocked CD20 Cell-Signaling in Rituximab-Resistant B-NHL By the Fusion Protein Anti-CD20-hIFN-Alpha

Gabriel G Vega, PhDstudent, Luz A Franco-Cea, Sara Huerta-Yepez, PhD, Hector Mayani, PhD, Otoniel Martinez-Maza, PhD, Benjamin Bonavida, PhD, Mario I. Vega, PhD

Blood (2015) 126 (23): 1468.

https://doi.org/10.1182/blood.V126.23.1468.1468

Published: 2015

Journal Articles

Yin Yang 1 (YY1) Regulates The Transcription Of The Gene Krüppel-Like Factor 4 ( KLF4 ) In Pediatric Burkitt Lymphoma: Clinical Implications

Mario I Vega, PhD, Alberto Valencia-Hipolito, MD/PhD, Miriam Hernandez-Atenogenes, ChB, Gabriel G Vega, MDVZ/PhD, Hector Mayani, PhD, Sara Huerta-Yepez, PhD, Benjamin Bonavida, Ph.D, Otoniel Martinez-Maza, PhD

Blood (2013) 122 (21): 3004.

https://doi.org/10.1182/blood.V122.21.3004.3004

Published: 2013

Journal Articles

Inhibition of B-NHL Tumor Xenografts Following Treatment with Galiximab (Anti-CD80 mAb) and Potentiation When Combined with Chemotherapy

Mario I Vega, PhD, Hari Hariharan, PhD, Peter Chu, PhD, Tracey Murphy, PhD, Dana Clanton, PhD, Lisa Berquist, PhD, Arturo Molina, PhD, Steffan Ho, PhD, Benjamin Bonavida, Ph.D

Blood (2012) 120 (21): 4873.

https://doi.org/10.1182/blood.V120.21.4873.4873

Published: 2012

Journal Articles

HIF-1α Induces a Chemoresistance Phenotype in a Non-Hodgkin‘s Lymphoma Cell Line Via up-Regulation of Bcl- xL

Marco A Hernandez-Luna, M Sc, Leticia Rocha-Zavaleta, PhD, Mario I Vega, PhD, Sara Huerta-Yepez, PhD

Blood (2012) 120 (21): 5091.

https://doi.org/10.1182/blood.V120.21.5091.5091

Published: 2012

Journal Articles

Upregulation of KLF4 Expression in Pediatric B-NHL Lymphomas and Its Association with Low EFS and Poor Survival Following Treatment with Chemotherapy

Mario I Vega, PhD, Miriam Hernandez-Atenogenes, ChB, Alberto Valencia, MD, Gabriel G Vega, MDVZ, Altagracia Maldonado-Valenzuela, ChB, Guillermo Ramon, MD, Haiming Chen, James R. Berenson, MD, Otoniel Martinez-Maza, PhD, Hector Mayani, PhD, Sara Huerta-Yepez, PhD, Benjamin Bonavida, Ph.D

Blood (2011) 118 (21): 5184.

https://doi.org/10.1182/blood.V118.21.5184.5184

Published: 2011

Journal Articles

Unresponsiveness to CHOP Is Associated with Activation of the p38 MAPK Pathway in Patients with DLBCL

Mario I Vega, PhD, Alejandro Aviles-Salas, MD, J Ramon Chalapud, MD, Sara Huerta-Yepez, PhD, Rogelio Hernandez-Pando, MD, PhD, Melisa Martinez-Paniagua, BSc, MSc, Bernardo Martinez-Miguel, BCh, Miriam Hernandez-Atenogenes, ChB, Gabriel G Vega, MDVZ, Haiming Chen, James R. Berenson, MD, Hector Mayani, PhD, Otoniel Martinez-Maza, PhD, Benjamin Bonavida, Ph.D

Blood (2011) 118 (21): 2647.

https://doi.org/10.1182/blood.V118.21.2647.2647

Published: 2011

Journal Articles

Co-Overexpression of YY1 and Gp-170 (MDR1) in Childhood Acute Lymphocytic Leukemia (ALL): Transcription Regulation of Gp-170 by YY1 and Prognostic Significance,

Gabriela andres-Antonio, Jesus Rangel-Santiago, B.S., Ana B Tirado-Rodriguez, B.S., Elisa Dorantes-Acosta, MD MSc, Mario I Vega, PhD, Guillermo Aquino-Jarquin, PhD, Briseida Lopez, MD, Elba Jimenez, MD, Rosana Pelayo, PhD, Benjamin Bonavida, Ph.D, Aurora Medina-Sanson, MD, Sara Huerta-Yepez, PhD

Blood (2011) 118 (21): 3567.

https://doi.org/10.1182/blood.V118.21.3567.3567

Published: 2011

Journal Articles

Cytotoxic Activity of Anti-CD20-hIFN-α on Rituximab-Resistant B-NHL Clones and Synergy with Chemotherapy,

Gabriel G Vega, MDVZ, Mario I Vega, PhD, Sara Huerta-Yepez, Ph.D., Ali Jazirehi, PhD, Hector Mayani, PhD, Otoniel Martinez-Maza, PhD, Sherie Morrison, Benjamin Bonavida, Ph.D

Blood (2011) 118 (21): 3499.

https://doi.org/10.1182/blood.V118.21.3499.3499

Published: 2011

Journal Articles

The Overexpression of Inactive Phosphorylated Raf-1 Kinase Inhibitory Protein (RKIP) in Multiple Myeloma (MM) Regulates the Resistance to Bortezomib-Induced Cytotoxicity: Reversal of Resistance by the PKC Inhibitor Bisindolylmalemide

Sara Huerta-Yepez, PhD, Stavroula Baritaki, PhD, Hong Liu, Karla MC Mendez-Maldonado, B.S., Manuel L Penichet, M.D., Ph.D., Mario I Vega, PhD, Otoniel Martinez-Maza, PhD, Haiming Chen, James R. Berenson, MD, Devasis Chatterjee, PhD, Benjamin Bonavida, Ph.D

Blood (2011) 118 (21): 2892.

https://doi.org/10.1182/blood.V118.21.2892.2892

Published: 2011

Journal Articles

Rituximab Inhibits the PI3K/Akt Survival Pathway In B-NHL Cells Via Induction of the PTEN Tumor Suppressor: Pivotal Roles of the Inhibition of the PTEN Repressors Snail and YY1

Stavroula Baritaki, PhD, Eriko Suzuki, Ph.D, Mario I. Vega, PhD, Haiming Chen, MD, PhD, James R. Berenson, MD, Benjamin Bonavida, PhD

Blood (2010) 116 (21): 3152.

https://doi.org/10.1182/blood.V116.21.3152.3152

Published: 2010

Journal Articles

An ADCC-Independent Mechanism of Rituximab-Mediated B-NHL Cells Depletion Via Sensitization to Cell Death through the Expression of TRAIL on NK Cells

Mario I. Vega, PhD, Sara Huerta-Yepez, PhD, Melisa Martinez-Paniagua, BSc, MSc, Stavroula Baritaki, PhD, Benjamin Bonavida, PhD

Blood (2010) 116 (21): 4919.

https://doi.org/10.1182/blood.V116.21.4919.4919

Published: 2010

Journal Articles

Reversal of Drug/TRAIL-Resistant B-NHL Cells to Apoptosis by the Combination of Rituximab (anti-CD20) and Either Mapatumumab or Lexatumumab

Mario I. Vega, PhD, Sara Huerta-Yepez, PhD, Melisa Martinez-Paniagua, BSc, MSc, Stavroula Baritaki, PhD, Haiming Chen, MD, PhD, James R. Berenson, MD, Benjamin Bonavida, PhD

Blood (2010) 116 (21): 4931.

https://doi.org/10.1182/blood.V116.21.4931.4931

Published: 2010

Journal Articles

Photodynamic Therapy (PDT)-Mediated Inhibition of the Transcription Factor Yin Yang 1 (YY1) That Regulates Resistance In Lymphoma

Valentina Rapozzi, Ph.D, Sara Huerta-Yepez, PhD, Abhijeet Joshi, Mario I. Vega, PhD, Stavroula Baritaki, PhD, Luigi E. Xodo, Ph.D, Benjamin Bonavida, PhD

Blood (2010) 116 (21): 5113.

https://doi.org/10.1182/blood.V116.21.5113.5113

Published: 2010

Journal Articles

The Pivotal Role of Yin Yang 1 (YY1) Inhibition (and downstream Bcl-2/Bcl xl ) by Galiximab (anti-CD80 mAb) In the Reversal of Resistance of B-NHL Cells to Chemotherapy

Melisa Martinez-Paniagua, BSc, MSc, Mario I. Vega, PhD, Sara Huerta-Yepez, PhD, Hari Hariharan, PhD, Haiming Chen, MD, PhD, James R. Berenson, MD, Benjamin Bonavida, PhD

Blood (2010) 116 (21): 2887.

https://doi.org/10.1182/blood.V116.21.2887.2887

Published: 2010

Journal Articles

High Expression of Transcription Factor Yin Yang 1 and Multidrug Resistance Protein in Early B-Cell Precursors in Childhood Acute Lymphoblastic Leukemia.

Gabriela Antonio-Andres, MSc, Rosana Pelayo, PhD, Elisa Dorantes-Acosta, MD, Briseida Lopez-Martinez, MD, Belen Tirado-Rodriguez, BsC, Guadalupe Diaz-Elizondo, B.Sc., Mario I. Vega, PhD, Lourdes Arriaga-Pizano, PhD, Guillermina Juliana Baay-Guzmán, B.Sc., Daniel Hernandez-Cueto, Tech, Benjamin Bonavida, PhD, Aurora Medina-Sanson, MD, Sara Huerta-Yepez, PhD.

Blood (2009) 114 (22): 4695.

https://doi.org/10.1182/blood.V114.22.4695.4695

Published: 2009

Journal Articles

Upregulation of Krüppel-Like Factor 4 (KLF-4) Expression as a Potential Tumor Progression Gene Product in Non-Hodgkin's Lymphoma.

Mario I. Vega, PhD, Juan vazquez-Islas, Melisa Martinez-Paniagua, Miriam Hernandez-Atenogenes, Bernardo martinez-Miguel, Altagracia Maldonado-Valenzuela, B.Sc., Cesar Gonzalez-Bonilla, Sara Huerta-Yepez, PhD., Otoniel Martinez-Maza, Ph.D., Benjamin Bonavida, PhD

Blood (2009) 114 (22): 5022.

https://doi.org/10.1182/blood.V114.22.5022.5022

Published: 2009

NARROW

A Deptor Inhibitor Induces Its Degradation with Resulting Anti-Myeloma Cytotoxicity in Vitro and In Vivo

Role of the microRNA-7 (miR-7) in the Inhibition of Chemoresistance and Migration of Lymphoma Non-Hodgkin's through Regulation of YY1 and KLF4

Fusion Protein Ompc-CD154 Inhibits Proliferation and Induces Apoptosis in B-NHL Cell Lines By a Mechanism That Involves MAPK P38 and TRAF2 Activation

KLF4 and YY1 Are Resistant Factors in NHL and Potential Therapeutic Targets: The New Resistant NF-κb/YY1/KLF4/Bcl xL /Mcl-1 Axis

Cooperation Between the CD20 Receptor and hIFN-Alpha Receptor in Overriding the Blocked CD20 Cell-Signaling in Rituximab-Resistant B-NHL By the Fusion Protein Anti-CD20-hIFN-Alpha

Yin Yang 1 (YY1) Regulates The Transcription Of The Gene Krüppel-Like Factor 4 ( KLF4 ) In Pediatric Burkitt Lymphoma: Clinical Implications

Inhibition of B-NHL Tumor Xenografts Following Treatment with Galiximab (Anti-CD80 mAb) and Potentiation When Combined with Chemotherapy

HIF-1α Induces a Chemoresistance Phenotype in a Non-Hodgkin‘s Lymphoma Cell Line Via up-Regulation of Bcl- xL

Upregulation of KLF4 Expression in Pediatric B-NHL Lymphomas and Its Association with Low EFS and Poor Survival Following Treatment with Chemotherapy

Unresponsiveness to CHOP Is Associated with Activation of the p38 MAPK Pathway in Patients with DLBCL

Co-Overexpression of YY1 and Gp-170 (MDR1) in Childhood Acute Lymphocytic Leukemia (ALL): Transcription Regulation of Gp-170 by YY1 and Prognostic Significance,

Cytotoxic Activity of Anti-CD20-hIFN-α on Rituximab-Resistant B-NHL Clones and Synergy with Chemotherapy,

The Overexpression of Inactive Phosphorylated Raf-1 Kinase Inhibitory Protein (RKIP) in Multiple Myeloma (MM) Regulates the Resistance to Bortezomib-Induced Cytotoxicity: Reversal of Resistance by the PKC Inhibitor Bisindolylmalemide

Rituximab Inhibits the PI3K/Akt Survival Pathway In B-NHL Cells Via Induction of the PTEN Tumor Suppressor: Pivotal Roles of the Inhibition of the PTEN Repressors Snail and YY1

An ADCC-Independent Mechanism of Rituximab-Mediated B-NHL Cells Depletion Via Sensitization to Cell Death through the Expression of TRAIL on NK Cells

Reversal of Drug/TRAIL-Resistant B-NHL Cells to Apoptosis by the Combination of Rituximab (anti-CD20) and Either Mapatumumab or Lexatumumab

Photodynamic Therapy (PDT)-Mediated Inhibition of the Transcription Factor Yin Yang 1 (YY1) That Regulates Resistance In Lymphoma

The Pivotal Role of Yin Yang 1 (YY1) Inhibition (and downstream Bcl-2/Bcl xl ) by Galiximab (anti-CD80 mAb) In the Reversal of Resistance of B-NHL Cells to Chemotherapy

High Expression of Transcription Factor Yin Yang 1 and Multidrug Resistance Protein in Early B-Cell Precursors in Childhood Acute Lymphoblastic Leukemia.

Upregulation of Krüppel-Like Factor 4 (KLF-4) Expression as a Potential Tumor Progression Gene Product in Non-Hodgkin's Lymphoma.

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American Society of Hematology

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American Society of Hematology

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