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Maria Kleppe, PhD
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Journal Articles

Genomic and Proteomic Profiling of AF10-Fusion Oncoproteins Reveal Mechanisms of Leukemogenesis and Actionable Targets

Bo-Rui Chen, PhD, Anagha Deshpande, PhD, Maria Kleppe, PhD, Narayana Yeddula, PhD, Sunnie Yoh, PhD, Scott A. Armstrong, MD PhD, Ross L. Levine, MD, Sumit Chanda, PhD, Aniruddha J. Deshpande, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 544.
https://doi.org/10.1182/blood-2018-99-119210
Published: 2018
Journal Articles

Targeting Cell Non-Autonomous MAPK Activation As a Novel Therapeutic Strategy in Myeloproliferative Neoplasms

Sara C. Meyer, MD PhD, Nilabh Ghosh, MSc, Simona Stivala, PhD, Anne Baerenwaldt, PhD, Hui Hao-Shen, Stefan Dirnhofer, MD, Matthias S. Dettmer, MD, Cédric Simillion, PhD, Sophia Chiu, MSc, Matthew Keller, MSc, Maria Kleppe, PhD, Morgane Hilpert, PhD, Andreas S. Buser, MD, Jakob R. Passweg, MDMS, Thomas Radimerski, PhD, Radek C. Skoda, MD, Ross L. Levine, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 381.
https://doi.org/10.1182/blood.V130.Suppl_1.381.381
Published: 2017
Journal Articles

Genomic Landscapes in Elderly AML

Franck Rapaport, PhD, Timour Baslan, PhD, Ling Wang, MS, Caroline Sheridan, Tak Lee, Todd Hricik, Marc Robert de Massy, Leonid Telis, Yaseswini Neelamraju, Juan Medina, Larry D Cripe, MD, Martin S. Tallman, MD, Scott Lowe, PhD, Zhuoxin Sun, PhD, Yanming Zhang, MD, Donna S. Neuberg, ScD, Elisabeth Paietta, PhD, Ari Melnick, MD, Ross L. Levine, MD, Maria Kleppe, PhD, Francine E. Garrett-Bakelman, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 404.
https://doi.org/10.1182/blood.V130.Suppl_1.404.404
Published: 2017
Journal Articles

JAK1 As a Convergent Regulator of Hematopoietic Stem Cell Function and Stress Hematopoiesis

Maria Kleppe, PhD, Matthew H Spitzer, PhD, Sheng Li, PhD, Lauren Dong, M.S., Efthymia Papalexi, Corinne Hill, M.S, Sofie De Groote, M.S., Matthew Keller, M.S., Priya Koppikar, PhD, Franck Rapaport, PhD, Jorge Gandara, Christopher E. Mason, PhD, Garry P. Nolan, Prof, PhD, Ross L. Levine, MD
Journal: Blood
Blood (2016) 128 (22): 722.
https://doi.org/10.1182/blood.V128.22.722.722
Published: 2016
Journal Articles

Lysine-Specific Histone Demethylase, LSD1, (KDM1A) As a Novel Therapeutic Target in Myeloproliferative Neoplasms

Maria Kleppe, PhD, Kaitlyn Shank, BS, Papalexi Efthymia, BS, Hugh Riehnhoff, MD, Ross L. Levine, MD
Journal: Blood
Blood (2015) 126 (23): 601.
https://doi.org/10.1182/blood.V126.23.601.601
Published: 2015
Journal Articles

Type II Inhibition of JAK2 with NVP-CHZ868 Reverses Type I JAK Inhibitor Persistence and Demonstrates Increased Efficacy in MPN Models

Sara C Meyer, MD PhD, Matthew D Keller, BS, Priya Koppikar, PhD, Olga A Guryanova, MD PhD, Maria Kleppe, PhD, Anna Sophia McKenney, MPH, William R Sellers, MD, Francesco Hofmann, PhD, Fabienne Baffert, Christoph Gaul, PhD, Thomas Radimerski, PhD, Ross L Levine, MD
Journal: Blood
Blood (2014) 124 (21): 160.
https://doi.org/10.1182/blood.V124.21.160.160
Published: 2014