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Marcel R.M. van den Brink, MD PhD.
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Journal Articles

RIG-I Activation Is Critical for Responsiveness to Checkpoint Blockade

Simon Heidegger, MD, Alexander Wintges, Florian Stritzke, Katja Steiger, Paul-Albert Koenig, Thomas Engleitner, Julius Clemens Fischer, Vladimir Makarov, Christof Winter, Roland Rad, Marcel R.M. van den Brink, MD PhD, Jürgen Ruland, Florian Bassermann, MD PhD, Timothy Chan, Tobias Haas, MD, Hendrik Poeck, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 624.
https://doi.org/10.1182/blood-2019-128724
Published: 2019
Journal Articles

Antibiotic Exposures and Dietary Intakes Are Associated with Changes in Microbiota Compositions in Allogeneic Hematopoietic Stem Cell Transplant Patients

Chi L. Nguyen, BA, Antonio L.C. Gomes, PhD, Jonathan U. Peled, MD PhD, John B. Slingerland, BSc, Ann E. Slingerland, BSc, Marissa L. Buchan, MS, Peter A. Adintori, MS, RD, CDN, Kate A Markey, PhDMBBS,FRACP, Annelie Clurman, BA, Molly A. Maloy, MS, Sergio A. Giralt, MD, Miguel-Angel Perales, MD, Ying Taur, MD MPH, Xavier B. Joao, PhD, Eric G. Pamer, MD, Marcel R.M. van den Brink, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 597.
https://doi.org/10.1182/blood-2019-130578
Published: 2019
Journal Articles

Sparing of the Lower Gastrointestinal Tract Microbiota Is Associated with Reduced Acute Graft-Versus-Host Disease

Doris M Ponce, MD, Marina D Burgos da Silva, PhD, Antonio L.C. Gomes, PhD, Gillian Moore, BA, John B. Slingerland, BSc, Eric G. Pamer, MD, Ying Taur, MD MPH, Jonathan U. Peled, MD PhD, Marcel R.M. van den Brink, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4538.
https://doi.org/10.1182/blood-2019-131067
Published: 2019
Journal Articles

The Blood Microbiome Predicts Acute Graft-Versus-Host Disease after Stem Cell Transplantation

Lily Blair, PhD, Jonathan U. Peled, MD, Paul A Giardina, John B. Slingerland, BSc, Ann E. Slingerland, BSc, Desiree Hollemon, MPH, MSN, Carine Ho, Sivan Bercovici, Asim Ahmed, David K Hong, MD, Sergio A. Giralt, MD, Ying Taur, MD MPH, Marcel R.M. van den Brink, MD PhD, Kate A Markey, PhDMBBS,FRACP
Journal: Blood
Blood (2019) 134 (Supplement_1): 4513.
https://doi.org/10.1182/blood-2019-129272
Published: 2019
Journal Articles

Financial Incentives to Increase Stool Collection Rates for Microbiome Studies in Adult Bone Marrow Transplant Patients

Jillian C. Thompson, MS, Yi Ren, MS, Kristi M. Romero, BS, Meagan V. Lew, BS, Amy T. Bush, BS, Julia A. Messina, MD, Sin-Ho Jung, PhD, Julie M. Miller, PhD, Zachary Zenko, PhD, Robert R. Jenq, MD, Jonathan U. Peled, MD, Marcel R.M. van den Brink, MD PhD, Nelson J. Chao, MD, Anthony D. Sung, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5775.
https://doi.org/10.1182/blood-2019-128702
Published: 2019
Journal Articles

Pre-Transplant Fecal Microbial Diversity Independently Predicts Critical Illness after Hematopoietic Cell Transplantation

Fatima I. Adhi, MD, Eric R. Littmann, BA, Ying Taur, MD MPH, Molly A. Maloy, MS, Kate A Markey, PhDMBBS,FRACP, Emily Fontana, BA, Luigi A Amoretti, B.S., Roberta Wright, M.S., M.B.S., Miriam Sanchez-Escamilla, MD, Nerea Castillo Flores, MD PhD, Ana Alarcon Tomas, MD, Richard J Lin, MD PhD, Lucrecia Yáñez, MD PhD, Daniel Brereton, B.A., Annelie Clurman, BA, John B. Slingerland, BSc, Gunjan L. Shah, MD, Christina Cho, MD, Michael Scordo, MD, Ioannis Politikos, MD, Boglarka Gyurkocza, MD, Doris M Ponce, MD, Juliet Barker, MBBS, Miguel-Angel Perales, MD, Sergio A Giralt, MD, Marcel R.M. van den Brink, MD PhD, Eric G. Pamer, MD, Jonathan U. Peled, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3264.
https://doi.org/10.1182/blood-2019-124902
Published: 2019
Journal Articles

A High Degree of Engrafting Unit-Recipient HLA-Allele Mismatch Is Not Associated with an Increased Risk of Transplant-Related Mortality (TRM) or Inferior Progression-Free Survival (PFS) after Double Unit Cord Blood (CB) Transplantation (dCBT) in Adults with Hematologic Malignancies

Ioannis Politikos, MD, Sean M Devlin, PhD, Molly Maloy, MS, Christopher Mazis, BS, Kristine Naputo, BA, Aishat Olaide Afuye, BA, Andromachi Scaradavou, MD, Scott T Avecilla, MD PhD, Hugo R. Castro-Malaspina, MD, Christina Cho, MD, Parastoo B. Dahi, MD, Sergio Giralt, MD, Boglarka Gyurkocza, MD, Ann A. Jakubowski, MDPhD, Esperanza B. Papadopoulos, MD, Miguel-Angel Perales, MD, Craig S. Sauter, MD, Michael Scordo, MD, Brian C. Shaffer, MD, Gunjan L. Shah, MD, Roni Tamari, MD, Marcel R.M. van den Brink, MD PhD, James W. Young, MD, Doris Ponce, MD, Juliet Barker, MBBS
Journal: Blood
Blood (2018) 132 (Supplement 1): 3470.
https://doi.org/10.1182/blood-2018-99-116477
Published: 2018
Journal Articles

Evaluation of Cord Blood (CB) Unit TNC & CD34+ Cell Content & Donor-Recipient High-Resolution 8 HLA-Allele Match By Patient Ancestry: An Evaluation of 513 CB Units in a Racially & Ethnically Diverse Population of Adults with Hematologic Malignancies

Christopher Mazis, BS, Ioannis Politikos, MD, Sean M Devlin, PhD, Molly Maloy, MS, Eric Davis, MPH, Candice Cooper, Melissa Nhaissi, MPH, Beth Suri, Deborah Wells, Sergio Giralt, MD, Gunjan L. Shah, MD, Marcel R.M. van den Brink, MD PhD, Nancy A. Kernan, Andromachi Scaradavou, MD, Juliet Barker, MBBS
Journal: Blood
Blood (2018) 132 (Supplement 1): 3342.
https://doi.org/10.1182/blood-2018-99-116598
Published: 2018
Journal Articles

Intestinal Microbiota Composition Prior to CAR T Cell Infusion Correlates with Efficacy and Toxicity

Melody Smith, MD, Eric R. Littmann, BA, John B. Slingerland, BSc, Annelie Clurman, BA, Ann E. Slingerland, BSc, Ying Taur, MD MPH, Jonas Schluter, PhD, Jae H. Park, MD, Roisin O'Cearbhaill, MD, Sham Mailankody, MBBS, Eric L. Smith, MD PhD, Maria Lia Palomba, MD, Oladapo Yeku, MD PhD, Jonathan U. Peled, MD, Elizabeth Halton, NP-BC AOCNP, Claudia Diamonte, RN, Jason Chan, Malloury Hall, BA, Pavan Anant, BS, Peter Kane, BA, Sergio Giralt, MD, Isabelle Riviere, PhD, Renier J. Brentjens, MD PhD, Eric G. Pamer, MD, Marcel R.M. van den Brink, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3492.
https://doi.org/10.1182/blood-2018-99-118628
Published: 2018
Journal Articles

Intestinal Enterococcus Is a Major Risk Factor for the Development of Acute Gvhd

Christoph K. Stein-Thoeringer, MD, Jonathan U. Peled, MD PhD, Antonio LC Gomes, PhD, Amina Lazrak, BS, Melissa D Docampo, BS, Ann E. Slingerland, BSc, Katherine Nichols, BS, Yusuke Shono, MD PhD, Daniela Weber, MD, Anthony D. Sung, MD, Daigo Hashimoto, MD, PhD, Justin Cross, PhD, Takanori Teshima, Ernst Holler, MD, Nelson J. Chao, MD, Eric G. Pamer, MD, Marcel R.M. van den Brink, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 358.
https://doi.org/10.1182/blood-2018-99-119887
Published: 2018
Journal Articles

Loss of Microbiota Diversity after Autologous Stem Cell Transplant Is Comparable to Injury in Allogeneic Stem Cell Transplant

Niloufer Khan, MD, Jonathan U. Peled, MD PhD, Antonio LC Gomes, PhD, Sean M Devlin, PhD, Carlos Rondon-Clavo, MD, Annelie Clurman, BA, John B. Slingerland, BSc, Ann E. Slingerland, BSc, Molly Maloy, MS, Anthony D. Sung, MD, Nelson J. Chao, MD, Craig S. Sauter, MD, Heather J. Landau, MD, Doris Ponce, MD, Boglarka Gyurkocza, MD, Gunjan L. Shah, MD, Michael Scordo, MD, Parastoo B. Dahi, MD, Miguel-Angel Perales, MD, Robert R. Jenq, MD, Sergio Giralt, MD, Eric G. Pamer, MD, Marcel R.M. van den Brink, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 608.
https://doi.org/10.1182/blood-2018-99-110857
Published: 2018
Journal Articles

Expression of the Butyrate/Niacin Receptor, GPR109a on T Cells Plays an Important Role in a Mouse Model of Graft Versus Host Disease

Melissa D Docampo, BS, Christoph K. Stein-Thoeringer, MD, Amina Lazrak, BS, Marina D Burgos da Silva, PhD, Justin Cross, PhD, Marcel R.M. van den Brink, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 61.
https://doi.org/10.1182/blood-2018-99-118783
Published: 2018
Journal Articles

Double-Unit Cord Blood (CB) Transplantation with Haplo-Identical CD34+ Cells (haplo-dCBT) May Speed Neutrophil Recovery Although Successful Bridging Is Contingent on Close Haplo-Winning CB Unit HLA-Match

Ioannis Politikos, MD, Sean M Devlin, PhD, Christopher Mazis, BS, Molly Maloy, MS, Kristine Naputo, BA, Aishat Olaide Afuye, BA, Valkal Bhatt, PharmD, BCOP, BCPS, Andromachi Scaradavou, MD, Richard J. O'Reilly, MD, Scott T Avecilla, MD PhD, Hugo R. Castro-Malaspina, MD, Christina Cho, MD, Parastoo B. Dahi, MD, Sergio Giralt, MD, Boglarka Gyurkocza, MD, Katharine C. Hsu, MD PhD, Ann A. Jakubowski, MD PhD, Esperanza B. Papadopoulos, MD, Miguel-Angel Perales, MD, Craig S. Sauter, MD, Michael Scordo, MD, Brian C. Shaffer, MD, Gunjan L. Shah, MD, Roni Tamari, MD, Marcel R.M. van den Brink, MD PhD, James W. Young, MD, Doris Ponce, MD, Juliet Barker, MBBS
Journal: Blood
Blood (2018) 132 (Supplement 1): 2078.
https://doi.org/10.1182/blood-2018-99-116276
Published: 2018
Journal Articles

Multicenter Microbiota Analysis Indicates That Pre-HCT Microbiota Injury Is Prevalent across Geography and Predicts Poor Overall Survival

Jonathan U. Peled, MD PhD, Antonio LC Gomes, PhD, Christoph K. Stein-Thoeringer, MD, John B. Slingerland, BSc, Ann E. Slingerland, BSc, Daniela Weber, MSc, Kate A Markey, PhDMBBS, Melody Smith, MD, Doris Ponce, MD, Annelie Clurman, BA, Anthony D. Sung, MD, Daigo Hashimoto, MD, PhD, Molly Maloy, MS, Niloufer Khan, MD, Boglarka Gyurkocza, MD, Sergio Giralt, MD, Miguel-Angel Perales, MD, Robert R. Jenq, MD, Ying Taur, MD MPH, Xavier B. Joao, PhD, Eric G. Pamer, MD, Takanori Teshima, Nelson J. Chao, MD, Ernst Holler, MD, Marcel R.M. van den Brink, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 811.
https://doi.org/10.1182/blood-2018-99-116967
Published: 2018
Journal Articles

Pre-Transplant and Peri-d100 Gastrointestinal Dysbiosis Is Associated with the Subsequent Development of Chronic Graft-Versus-Host Disease

Kate A Markey, PhDMBBS, Antonio LC Gomes, PhD, Eric R. Littmann, BA, Sean M Devlin, PhD, Ann E. Slingerland, BSc, John B. Slingerland, BSc, Annelie Clurman, BA, Gillian Moore, BA, Samira A Fatmi, BS, Molly Maloy, MS, Eric G. Pamer, MD, Ying Taur, MD MPH, Sergio Giralt, MD, Miguel-Angel Perales, MD, Doris Ponce, MD, Jonathan U. Peled, MD PhD, Marcel R.M. van den Brink, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 359.
https://doi.org/10.1182/blood-2018-99-110309
Published: 2018
Journal Articles

Intestinal Microbiota Composition Is Associated with Minimal Residual Disease Negativity in Patients with Multiple Myeloma

Matthew J. Pianko, MD, Sean M Devlin, PhD, Eric R. Littmann, BA, Aisara Chansakul, BS, Donna Mastey, RN, Meghan Salcedo, RN, Emily Fontana, BA, Lilan Ling, BS, Elizabet Tavitian, BS, John B. Slingerland, BSc, Ann E. Slingerland, BSc, Annelie Clurman, BA, Antonio LC Gomes, PhD, Ying Taur, MD MPH, Eric G. Pamer, MD, Jonathan U. Peled, MD PhD, Marcel R.M. van den Brink, MD PhD, Ola Landgren, MD PhD, Alexander M. Lesokhin, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3167.
https://doi.org/10.1182/blood-2018-99-117719
Published: 2018
Journal Articles

Tumor-Intrinsic RIG-I Signaling Promotes Anti-CTLA-4 Checkpoint Inhibitor-Mediated Anticancer Immunity

Simon Heidegger, MD, Alexander Wintges, Sarah Bek, Martina Schmickl, Jürgen Ruland, MD, Marcel R.M. van den Brink, MD PhD, Christian Peschel, MD, Tobias Haas, MD, Hendrik Poeck, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 693.
https://doi.org/10.1182/blood.V130.Suppl_1.693.693
Published: 2017
Journal Articles

Mechanisms Governing Endogenous Thymic Regeneration

Tobias Wertheimer, Enrico Velardi, PhD BS, Jennifer Tsai, MD PhD, Kirsten Cooper, Katja J Ottmüller, Zeinab Mokthari, Jason M. Butler, PhD, Shahin Rafii, MD, Marcel R.M. van den Brink, MD PhD, Jarrod A Dudakov, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 66.
https://doi.org/10.1182/blood.V130.Suppl_1.66.66
Published: 2017
Journal Articles

Intestinal Microbiota Injury during Allo-Hsct Is Generalizable across Transplantation Centers and Is Associated with Increased Mortality, Broad-Spectrum Antibiotics, and Decreased Calorie Intake

Jonathan U. Peled, MD, Antonio Gomes, PhD, Marissa L. Buchan, MS, Christoph K. Stein-Thoeringer, MD, John B. Slingerland, BS, Ann E. Slingerland, BS, Daniela Weber, MSc, Anthony D. Sung, MD, Molly Maloy, MS, Tatanisha Peets, MPH, RD, Sergio A. Giralt, MD, Robert R. Jenq, MD, Ying Taur, MD MPH, Xavier B. Joao, PhD, Eric G. Pamer, MD, Nelson J. Chao, MDM.B.A, Ernst Holler, MD, Marcel R.M. van den Brink, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 750.
https://doi.org/10.1182/blood.V130.Suppl_1.750.750
Published: 2017
Journal Articles

Nrf2 Is a Critical Mediator of CD4 T Cell-Induced Acute Graft-Versus-Host Disease

Jennifer Tsai, MD PhD, Enrico Velardi, PhD BS, Yusuke Shono, MD PhD, Kimon Argyropoulos, MD, Odette M. Smith, BA, Amina Lazrak, BS, Chen Liu, MD PhD, George F Murphy, MD, Ya-Yuan Fu, PhD, Alan M. Hanash, Robert R. Jenq, MD, Jarrod A Dudakov, PhD, Marcel R.M. van den Brink, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 205.
https://doi.org/10.1182/blood.V130.Suppl_1.205.205
Published: 2017