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Journal Articles

FOXM1 Mediates Drug-Resistance and Represents a Therapeutic Target in Pre-B Acute Lymphoblastic Leukemia

Maike Buchner, PhD, Eugene Park, Lars Klemm, Huimin Geng, PhD, Dragana Kopanja, Pradip Raychaudhuri, PhD, Markus Muschen, MDPhD

Blood (2014) 124 (21): 790.

https://doi.org/10.1182/blood.V124.21.790.790

Published: 2014

Journal Articles

Harnessing Negative B Cell Selection to Overcome Drug-Resistance in Acute Lymphoblastic Leukemia

Zhengshan Chen, MD PhD, Seyedmehdi Shojaee, PhD, Huimin Geng, PhD, Jae-Woong Lee, PhD, Maike Buchner, PhD, Lars Klemm, Clifford A. Lowell, MD PhD, Elisabeth Paietta, PhD, Cheryl L. Willman, MD, William L. Carroll, MD, Ari Melnick, MD, Jae U. Jung, PhD, Hassan Jumaa, PhD, John E. Coligan, PhD, Silvia Bolland, PhD, Tak W. Mak, OC, PhD DSc, FRSC, FRS, Markus Muschen, MDPhD

Blood (2014) 124 (21): 792.

https://doi.org/10.1182/blood.V124.21.792.792

Published: 2014

Journal Articles

PTEN Is Essential for Normal Cytokine Signaling and Oncogenic Transformation of Pre-B Cells

Seyedmehdi Shojaee, PhD, Valeria Cazzaniga, Hilde Schjerven, PhD, Maike Buchner, PhD, Christian Hurtz, PhD, Huimin Geng, PhD, Andreas Hochhaus, MD, Giovanni Cazzaniga, PhD, Ari M Melnick, MD, Steven M. Kornblau, MD, Thomas G Graeber, PhD, Markus Muschen, MD PhD

Blood (2014) 124 (21): 262.

https://doi.org/10.1182/blood.V124.21.262.262

Published: 2014

Journal Articles

Erk and Stat5 Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia

Shojaee Seyedmehdi, PhD, Zhengshan Chen, MD PhD, Maike Buchner, PhD, Christian Hurtz, PhD, Huimin Geng, PhD, Hilde Schjerven, PhD, Lai N Chan, PhD, Phillip Koeffler, MD, Cheryl L. Willman, MD, Stephen Hunger, MD, Sinisa Dovat, MD,PhD, Elisabeth Paietta, PhD, Wolf-Karsten Hofmann, Ari M Melnick, MD, Warren S. Alexander, Steven M. Kornblau, MD, Markus Muschen, MDPhD

Blood (2014) 124 (21): 787.

https://doi.org/10.1182/blood.V124.21.787.787

Published: 2014

Journal Articles

The Linker Protein GAS7 Negatively Regulates Pre-B Cell Differentiation and Amplifies Proliferation and Survival Signals in Acute Lymphoblastic Leukemia

Jae-Woong Lee, PhD, Maike Buchner, PhD, Huimin Geng, PhD, Srividya Swaminathan, PhD, Eugene Park, Angela Park, Sue Lin-Chao, Chi Wai So, Markus Muschen, MD PhD

Blood (2014) 124 (21): 3777.

https://doi.org/10.1182/blood.V124.21.3777.3777

Published: 2014

Journal Articles

Gas7 Induces The Proliferation Of Ph + ALL Cells and Prevents The Differentiation Of Early B Cell Progenitors Into CD25 high Small Pre-B Cells

Jaewoong Lee, PhD, Maike Buchner, PhD, Huimin Geng, PhD, Srividya Swaminathan, PhD, Eugene Park, Lars Klemm, Sue Lin-Chao, Chi Wai So, Markus Muschen, MD, PhD

Blood (2013) 122 (21): 2506.

https://doi.org/10.1182/blood.V122.21.2506.2506

Published: 2013

Journal Articles

Identification Of FOXM1 As Therapeutic Target In BCR-ABL1 Positive Acute Lymphoblastic Leukemia

Maike Buchner, PhD, Eugene Park, Lars Klemm, MSc, Huimin Geng, PhD, Dragana Kopanja, Pradip Raychaudhuri, PhD, Markus Muschen, MD, PhD

Blood (2013) 122 (21): 1250.

https://doi.org/10.1182/blood.V122.21.1250.1250

Published: 2013

Journal Articles

Inhibitory Receptors and Phosphatases Enable Oncogenic Tyrosine Kinase Signaling In B Cell Lineage Leukemia

Zhengshan Chen, MD, PhD, Seyedmehdi Shojaee, PhD, Huimin Geng, PhD, Jaewoong Lee, PhD, Maike Buchner, PhD, Lars Klemm, Clifford A. Lowell, MD, PhD, Elisabeth Paietta, PhD, Cheryl L. Willman, MD, William L. Carroll, MD, Ari M. Melnick, MD, Jae U. Jung, PhD, Hassan Jumaa, PhD, John E. Coligan, PhD, Silvia Bolland, PhD, Tak W. Mak, Markus Muschen, MD, PhD

Blood (2013) 122 (21): 229.

https://doi.org/10.1182/blood.V122.21.229.229

Published: 2013

Journal Articles

Negative Feedback Signaling Enables Leukemic Transformation by Oncogenic Tyrosine Kinases

Seyedmehdi Shojaee, M.Sc., Maike Buchner, PhD, Srividya Swaminathan, B Tech, Huimin Geng, PhD, Linda Chan, PhD, Marle Bothe, Zhengshan Chen, MD, PhD, Ari Melnick, MD, Jeffery Molkentin, PhD, Gail Martin, PhD, H. Phillip Koeffler, MD, Markus Muschen, MD, PhD

Blood (2012) 120 (21): 1352.

https://doi.org/10.1182/blood.V120.21.1352.1352

Published: 2012

Journal Articles

Suppressor of Cytokine Signaling (SOCS) Molecules Are Critical to Balance Oncogenic Signaling Strength in Ph + ALL.

Zhengshan Chen, MD, PhD, Huimin Geng, PhD, Lars Klemm, Maike Buchner, PhD, Kaveh Hemati, BS, Seyedmehdi Shojaee, M.Sc., Warren S. Alexander, William L. Carroll, MD, Cheryl L Willman, MD, Markus Muschen, MD

Blood (2012) 120 (21): 2563.

https://doi.org/10.1182/blood.V120.21.2563.2563

Published: 2012

Journal Articles

ITIM-Containing Inhibitory Receptors Are Required to Balance Oncogenic Signaling Strength in Ph + ALL

Zhengshan Chen, MD, PhD, Huimin Geng, PhD, Maike Buchner, PhD, Lars Klemm, MSc, Kaveh Hemati, BS, Seyedmehdi Shojaee, M.Sc., Mak W Tak, PhD, John E Coligan, PhD, William L. Carroll, MD, Cheryl L Willman, MD, Markus Muschen, MD

Blood (2012) 120 (21): 291.

https://doi.org/10.1182/blood.V120.21.291.291

Published: 2012

Journal Articles

Integrative Analysis of Ikaros-Dependent Changes of Transcriptional Regulation and Tyrosine Phosphorylation Events in Ph + ALL

Huimin Geng, PhD, Rahul Nahar, PhD, Parham Ramezani-Rad, Zhengshan Chen, MD, PhD, Jeffrey W. Tyner, PhD, Bill H. Chang, MD, PhD, Bjorn Titz, PhD, Maike Buchner, PhD, Christian Hurtz, Thomas G. Graeber, PhD, Brian J. Druker, Elisabeth Paietta, PhD, Ari Melnick, MD, Cheryl L. Willman, MD, William L. Carroll, MD, Markus Muschen, MD

Blood (2012) 120 (21): 528.

https://doi.org/10.1182/blood.V120.21.528.528

Published: 2012

Journal Articles

BACH2 Is Required for Pre-B Cell Receptor Checkpoint Control and p53-Dependent Tumor Surveillance

Srividya Swaminathan, B Tech, Huining Kang, PhD, Richard C. Harvey, PhD, Chuanxin Huang, PhD, Maike Buchner, PhD, Zhengshan Chen, MD, PhD, Huimin Geng, Andrew Hall, Kazuhiko Igarashi, PhD, William L. Carroll, MD, Cheryl L. Willman, MD, Ari Melnick, MD, Markus Muschen, MD, PhD

Blood (2012) 120 (21): 1300.

https://doi.org/10.1182/blood.V120.21.1300.1300

Published: 2012

Journal Articles

Identification of FoxM1 As Therapeutic Target in TKI-Resistant Ph + ALL

Maike Buchner, PhD, Lars Klemm, MSc, Chen Zhengshan, MD, PhD, Huimin Geng, PhD, Markus Muschen, MD

Blood (2012) 120 (21): 874.

https://doi.org/10.1182/blood.V120.21.874.874

Published: 2012

Journal Articles

SYK Inhibition Targets CD38−Mediated Survival and Proliferation Signals in Chronic Lymphocytic Leukemia Cells

Maike Buchner, PhD, Natalie Stickel, MS, Arlette Dörffel, BS, Ariane Ott, BS, Marcus Duehren von Minden, MS, Christine Dierks, MD, Hassan Jumaa, PhD, Hendrik J. Veelken, MD, PhD, Katja Zirlik, MD

Blood (2011) 118 (21): 800.

https://doi.org/10.1182/blood.V118.21.800.800

Published: 2011

Journal Articles

Spleen Tyrosine Kinase (SYK) Is Overexpressed and Represents a Potential Therapeutic Target in Chronic Lymphocytic Leukemia

Maike Buchner, PhD, Simon Fuchs, MS, Gabriele Prinz, BA, Dietmar Pfeifer, PhD, Kilian Bartholomé, PhD, Nina Chevalier, MD, Laurent Vallat, MD, Jens Timmer, PhD, John G Gribben, MD, DSc, Hassan Jumaa, PhD, Hendrik Veelken, MD, Christine Dierks, MD, Katja Zirlik, MD

Blood (2008) 112 (11): 543.

https://doi.org/10.1182/blood.V112.11.543.543

Published: 2008

NARROW

FOXM1 Mediates Drug-Resistance and Represents a Therapeutic Target in Pre-B Acute Lymphoblastic Leukemia

Harnessing Negative B Cell Selection to Overcome Drug-Resistance in Acute Lymphoblastic Leukemia

PTEN Is Essential for Normal Cytokine Signaling and Oncogenic Transformation of Pre-B Cells

Erk and Stat5 Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia

The Linker Protein GAS7 Negatively Regulates Pre-B Cell Differentiation and Amplifies Proliferation and Survival Signals in Acute Lymphoblastic Leukemia

Gas7 Induces The Proliferation Of Ph + ALL Cells and Prevents The Differentiation Of Early B Cell Progenitors Into CD25 high Small Pre-B Cells

Identification Of FOXM1 As Therapeutic Target In BCR-ABL1 Positive Acute Lymphoblastic Leukemia

Inhibitory Receptors and Phosphatases Enable Oncogenic Tyrosine Kinase Signaling In B Cell Lineage Leukemia

Negative Feedback Signaling Enables Leukemic Transformation by Oncogenic Tyrosine Kinases

Suppressor of Cytokine Signaling (SOCS) Molecules Are Critical to Balance Oncogenic Signaling Strength in Ph + ALL.

ITIM-Containing Inhibitory Receptors Are Required to Balance Oncogenic Signaling Strength in Ph + ALL

Integrative Analysis of Ikaros-Dependent Changes of Transcriptional Regulation and Tyrosine Phosphorylation Events in Ph + ALL

BACH2 Is Required for Pre-B Cell Receptor Checkpoint Control and p53-Dependent Tumor Surveillance

Identification of FoxM1 As Therapeutic Target in TKI-Resistant Ph + ALL

SYK Inhibition Targets CD38−Mediated Survival and Proliferation Signals in Chronic Lymphocytic Leukemia Cells

Spleen Tyrosine Kinase (SYK) Is Overexpressed and Represents a Potential Therapeutic Target in Chronic Lymphocytic Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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