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Journal Articles

A Novel Perspective on Stem Cells, Tissue Senescence and Aging: Pluripotent Very Small Embryonic-Like Stem Cells (VSELs) and Hematopoietic Stem Cells (HSCs) Are Prematurely Depleted in Adult Bone Marrow (BM) in Response to Prolonged Growth Hormone/Insulin-Like Growth Factor-1 Signaling (IIS) and Chronic Increase in Caloric Uptake

Magda Kucia, Ph.D., Janina Ratajczak, MD, PhD, Dong-Myung Shin, PhD, Rui Liu, Ph.D., Michal Masternak, Ph.D., Andrzej Bartke, Ph.D., Mariusz Z Ratajczak, M.D., Ph.D.

Blood (2011) 118 (21): 4818.

https://doi.org/10.1182/blood.V118.21.4818.4818

Published: 2011

Journal Articles

Novel View on Unwanted Side Effects of Radio-Chemotherapy on Bone Marrow (BM) Microenvironment - Radio-Chemotherapy Upregulates BM-Level of Bioactive Lipids, Sphingosine-1- Phosphate (S1P) and Ceramide-1-Phosphate (C1P), That Chemoattract Metastasizing Cancer Cells

Gabriela Schneider, Ph.D., Bryndza Ewa, MS, Chihwa Kim, Ph.D, Janina Ratajczak, MD, PhD, Magda Kucia, Ph.D., Mariusz Z Ratajczak

Blood (2011) 118 (21): 726.

https://doi.org/10.1182/blood.V118.21.726.726

Published: 2011

Journal Articles

Single Cell Level Genome-Wide Gene Expression Analysis of Bone Marrow-Derived Oct-4 + very Small Embryonic-Like Stem Cells (VSELs) Revealed That a Polycomb Group Protein Ezh2 Regulates VSELs Pluripotency by Maintaining Bivalent Domains At Promoters of Important Homeodomain-Containing Developmental Transcription Factors

Magda Kucia, Ph.D., Rui Liu, Ph.D., Kasia Mierzejewska, MS, Wan Wu, Ph.D., Janina Ratajczak, MD, PhD, Dong-Myung Shin, PhD, Mariusz Z Ratajczak

Blood (2011) 118 (21): 2345.

https://doi.org/10.1182/blood.V118.21.2345.2345

Published: 2011

Journal Articles

New Evidence That the Bioactive Lipid Ceramide-1-Phosphate (C1P) Is a Potent Chemoattractant for Mesenchymal Stromal Cells (MSC), Endothelial Progenitor Cells (EPCs) and Very Small Embryonic-Like Stem Cells (VSELs), Demonstrating Its Potential Involvement in Tissue/Organ Repair and Angiogenesis

ChiHwa Kim, Ph.D., Rui Liu, MB, BS, Magda Kucia, Ph.D., Mariusz Z Ratajczak, M.D., Ph.D.

Blood (2011) 118 (21): 2387.

https://doi.org/10.1182/blood.V118.21.2387.2387

Published: 2011

Journal Articles

Long-Term In Vivo Studies in Mice Unexpectedly Reveal That Prolonged Growth Hormone (GH) and Insulin/Insulin-Like Growth Factor-1 (IGF-1) Signaling Have a Negative Effect on Normal Bone Marrow Hematopoiesis – Implications for GH-Based “rejuvenation” Therapies,

Janina Ratajczak, MD, PhD, Rui Liu, Ph.D., Magda Kucia, Ph.D., Andrzej Bartke, Ph.D., Mariusz Z Ratajczak, MD, PhD, DSc

Blood (2011) 118 (21): 3422.

https://doi.org/10.1182/blood.V118.21.3422.3422

Published: 2011

Journal Articles

A Novel Perspective on Stem Cell Homing – Emerging Interplay Between Bioactive Lipids As Potent Chemoattractants and Cationic Peptides As Underappreciated Modulators of Responsiveness to SDF-1 Gradients

Chihwa Kim, Ph.D, Wu Wan, MS, Nicholas J. Greco, PhD, Magda Kucia, Ph.D., Janina Ratajczak, MD, PhD, Mary J. Laughlin, MD, Mariusz Z Ratajczak, MD, PhD, DSc

Blood (2011) 118 (21): 2957.

https://doi.org/10.1182/blood.V118.21.2957.2957

Published: 2011

Journal Articles

Novel View on Stem Cell Compartment and Aging - a Number of Pluripotent Very Small Embryonic Like Stem Cells and Hematopoietic Stem Cells in Murine Bone Marrow Is High in Several Long-Living and Reduced in Short-Living Murine Strains and Unexpectedly Inversely Correlates in These Animals with Plasma Growth Hormone/Insulin-Like Growth Factor-1 Level

Magda Kucia, Ph.D., Janina Ratajczak, MD, PhD, Rui Liu, MB, BS, Dong-Myung Shin, PhD, Michal Masternak, PhD, Andrzej Bartke, PhD, Mariusz Z Ratajczak, MD, PhD

Blood (2011) 118 (21): LBA-5–LAB-5.

https://doi.org/10.1182/blood.V118.21.LBA-5.LBA-5

Published: 2011

Journal Articles

Promotion of Chimerism and Tolerance by Flt3 Ligand-Mobilized Facilitating Cells Is Associated with Upregulation of CXCR4 and SDF-1.

Yiming Huang, M.D., Magda Kucia, Ph.D., Francine Rezzoug, Ph.D., Mariusz Z. Ratajczak, Ph.D., Michael Tanner, M.S., Carrie Schanie, M.S., Hong Xu, M.D., Isabelle Fugier, Ph.D., Suzanne T. Ildstad, M.D.

Blood (2004) 104 (11): 1286.

https://doi.org/10.1182/blood.V104.11.1286.1286

Published: 2004

NARROW

Novel View on Unwanted Side Effects of Radio-Chemotherapy on Bone Marrow (BM) Microenvironment - Radio-Chemotherapy Upregulates BM-Level of Bioactive Lipids, Sphingosine-1- Phosphate (S1P) and Ceramide-1-Phosphate (C1P), That Chemoattract Metastasizing Cancer Cells

New Evidence That the Bioactive Lipid Ceramide-1-Phosphate (C1P) Is a Potent Chemoattractant for Mesenchymal Stromal Cells (MSC), Endothelial Progenitor Cells (EPCs) and Very Small Embryonic-Like Stem Cells (VSELs), Demonstrating Its Potential Involvement in Tissue/Organ Repair and Angiogenesis

Long-Term In Vivo Studies in Mice Unexpectedly Reveal That Prolonged Growth Hormone (GH) and Insulin/Insulin-Like Growth Factor-1 (IGF-1) Signaling Have a Negative Effect on Normal Bone Marrow Hematopoiesis – Implications for GH-Based “rejuvenation” Therapies,

A Novel Perspective on Stem Cell Homing – Emerging Interplay Between Bioactive Lipids As Potent Chemoattractants and Cationic Peptides As Underappreciated Modulators of Responsiveness to SDF-1 Gradients

Promotion of Chimerism and Tolerance by Flt3 Ligand-Mobilized Facilitating Cells Is Associated with Upregulation of CXCR4 and SDF-1.

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American Society of Hematology

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American Society of Hematology

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