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Lisa Drew, PhD
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Journal Articles

TP53 Deficient/Mutant AMLs Are Resistant to Individual BH3 Mimetics: High Efficacy of Combined Inhibition of Bcl-2 and Mcl-1

Bing Z Carter, PhD, Po Yee Mak, Steven M. Kornblau, MD, Wenjing Tao, Yuki Nishida, MD PhD, Vivian Ruvolo, MS, Justin Cidado, PhD, Lisa Drew, PhD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1271.
https://doi.org/10.1182/blood-2019-124826
Published: 2019
Journal Articles

Inhibition of Anti-Apoptotic Mcl-1 Exerts Anti-Leukemia Activity through Modulation of Leukemia-Stromal Interactions and Metabolic Functions in AML

Bing Z Carter, PhD, Po Yee Mak, Marc Warmoes, Wenjing Tao, Philip Lorenzi, Vivian Ruvolo, MS, Lin Tan, Justin Cidado, PhD, Lisa Drew, PhD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3727.
https://doi.org/10.1182/blood-2019-124453
Published: 2019
Journal Articles

Combination of AZD4573, a Selective CDK9 Inhibitor, with Other Cell Death Inducing Agents Can Overcome De Novo Venetoclax Resistance in Preclinical Hematologic Tumor Models

Justin Cidado, PhD, Scott Boiko, MS, Theresa Proia, PhD, Haley Woods, MS, Omid Tavana, PhD, Maryann San Martin, MS, Adriana E. Tron, PhD, Wenlin Shao, PhD, Lisa Drew, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3946.
https://doi.org/10.1182/blood-2018-99-113423
Published: 2018
Journal Articles

Overcoming MCL1 Resistance in Multiple Myeloma

Ka Tat Siu, PhD, Cherrie Huang, Cristina Panaroni, PhD, Kenta Mukaihara, MD PhD, Keertik Fulzele, PhD, Rosemary Soucy, Justin Cidado, PhD, Lisa Drew, PhD, Shrikanta Chattopadhyay, MBBS, Noopur Raje, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 472.
https://doi.org/10.1182/blood-2018-99-116377
Published: 2018
Journal Articles

Mcl-1/CDK9 Targeting By AZD5991/AZD4573 Overcomes Intrinsic and Acquired Venetoclax Resistance in Vitro and In Vivo in PDX Model of AML through Modulation of Cell Death and Metabolic Functions

Bing Z Carter, PhD, Po Yee Mak, Wenjing Tao, Mark Warmoes, Philip L Lorenzi, PhD, Duncan Mak, BSc, MPhil, Vivian Ruvolo, MS, Xiangmeng Wang, Huaxian Ma, MS, Hong Mu, MD PhD, Justin Cidado, PhD, Lisa Drew, PhD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 768.
https://doi.org/10.1182/blood-2018-99-113491
Published: 2018
Journal Articles

Application of Hyperpolarized 13C Magnetic Resonance Imaging to Detect Target Inhibition of NFkB Activation in Preclinical Patient-Derived Models of CNS Lymphoma

Huimin Geng, PhD, Brice Tiret, PhD, Hua-Xin Gao, PhD, Cigall Kadoch, PhD, Ming Lu, PhD, Lingjing Chen, PhD, Ilwoo Park, PhD, Gerd Melkus, PhD, Adam Elkhaled, PhD, John Kurhanewicz, PhD, Lisa Drew, PhD, Sebastien Degorce, PhD, Michele Mayo, PhD, Keith Dillman, PhD, Rana Anjum, PhD, Andrew Bloecher, PhD, Myriam Chaumeil, PhD, James Rubenstein, MD, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2840.
https://doi.org/10.1182/blood-2018-99-117625
Published: 2018
Journal Articles

Selective Targeting Cyclin-Dependent Kinase-9 (CDK9) Downmodulates c-MYC and Induces Apoptosis in Diffuse Large B-Cell Lymphoma (DLBCL) Cells

Taylor Rowland, Cody Paiva, BS, Joelle Rowley, Andy Chen, MD PhD, Lisa Drew, PhD, Peter Hurlin, Bill H. Chang, MD PhD, Alexey V Danilov, MD PhD
Journal: Blood
Blood (2016) 128 (22): 289.
https://doi.org/10.1182/blood.V128.22.289.289
Published: 2016
Journal Articles

Targeting NF-KB Activation in Novel Intracranial Models of CNS Lymphoma

Huimin Geng, PhD, Huaxin Gao, PhD, Cigall Kadoch, PhD, Ming Lu, Lingjing Chen, PhD, Rana Anjum, PhD, Lisa Drew, PhD, Sebastien Degorce, PhD, Keith Dillman, Michele Mayo, Shawn Anderson, Colin Collins, PhD, Clifford A. Lowell, MD PhD, James L. Rubenstein, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 777.
https://doi.org/10.1182/blood.V128.22.777.777
Published: 2016