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Linda S. Higgins, PhD
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Journal Articles

SCIO-469, a Potent and Selective Inhibitor of the p38a MAPK, Inhibits TNFa-Induced Adhesion of Multiple Myeloma Cells to Bone Marrow Stromal Cells Via Downregulation of Chemokines CXCL10/IP-10 and CCL8.

Aaron N. Nguyen, PhD, Gilbert O’ Young, Diana Quon, Debby Damm, Ann M. Kapoun, PhD, Linda S. Higgins, PhD, Tony A. Navas, PhD
Journal: Blood
Blood (2005) 106 (11): 1569.
https://doi.org/10.1182/blood.V106.11.1569.1569
Published: 2005
Journal Articles

TGF-β Receptor I Kinase Inhibitor Downregulates Cytokine Secretion and Multiple Myeloma Cell Growth in the Bone Marrow Microenvironment.

Toshiaki Hayashi, MD, PhD, Teru Hideshima, MD, PhD, Klaus Podar, MD, PhD, Paul Richardson, MD, Olivier Munoz, MD, Makoto Hamasaki, MD, PhD, Kenji Ishitsuka, MD, PhD, Hiroshi Yasui, MD, PhD, Alison Murphy, PhD, Glenn McEnroe, PhD, Sarvajit Chakravarty, PhD, Sundeep Dugar, PhD, Linda S. Higgins, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2004) 104 (11): 2355.
https://doi.org/10.1182/blood.V104.11.2355.2355
Published: 2004
Journal Articles

P38 MAPK Inhibition Enhances PS-341 (bortezomib)-Induced Cytotoxicity Against Multiple Myeloma Cells.

Teru Hideshima, MD, PhD, Klaus Podar, MD, PhD, Dharminder Chauhan, PhD, Kenji Ishitsuka, MD, PhD, Constantine Mitsiades, MD, PhD, Yu-Tzu Tai, PhD, Makoto Hamasaki, MD, PhD, Noopur Raje, MD, Hiromasa Hideshima, George Schreiner, MD, PhD, Aaron Nguyen, PhD, Tony Navas, PhD, Nikhil C. Munshi, MD, Paul G. Richardson, MD, Linda S. Higgins, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2004) 104 (11): 3348.
https://doi.org/10.1182/blood.V104.11.3348.3348
Published: 2004
Journal Articles

SCIO-469, a Potent and Selective Inhibitor of p38a MAPK, Normalizes the Bone Marrow Microenvironment and Inhibits Multiple Myeloma Cell Proliferation in In Vitro and In Vivo Models.

Aaron N. Nguyen, PhD, Mamatha Reddy, MS, Margaret Henson, MS, Elizabeth G. Stebbins, PhD, Gilbert O’Young, BS, Jing Y. Ma, MD, Edwin Haghnazari, PhD, Ann M. Kapoun, PhD, Satya Medicherla, PhD, Andy Protter, PhD, Tony A. Navas, PhD, Linda S. Higgins, PhD
Journal: Blood
Blood (2004) 104 (11): 1501.
https://doi.org/10.1182/blood.V104.11.1501.1501
Published: 2004