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Journal Articles

On the Role of F8 Sequence Mismatch and Class-II Human Leukocyte Antigen Binding in the Development of Neutralizing Antibodies ("Inhibitors") Directed Against Therapeutic Factor VIII Proteins (tFVIIIs): Evidence from the PATH Study

Vincent P. Diego, PhD, Bernadette W. Luu, B.S., M.T. (CLS), Afshin Ameri, MD, Meera B. Chitlur, MD, Marcio A. Almeida, PhD, Karin Haack, PhD, Satish Kumar, PhD, Long V. Dinh, PhD, Henry Mead, M.B.A., M.P.H., Jerry S. Powell, MD, Miguel A. Escobar, MD, Raja Rajalingam, PhD, Sarah Williams-Blangero, PhD, Carol K. Kasper, MD, Laura Almasy, PhD, Shelley Cole, PhD, John Blangero, PhD, Tom E. Howard, MD, PhD

Blood (2019) 134 (Supplement_1): 2393.

https://doi.org/10.1182/blood-2019-132218

Published: 2019

Journal Articles

Genetics of Factor VIII Inhibitor Development in Hemophilia Patients: Novel Statistical Approaches in the PATH Study

Vincent P. Diego, PhD, Marcio A. Almeida, PhD, Bernadette W. Luu, BS, MT/CLS, Karin Haack, PhD, Meera B. Chitlur, MD, Afshin Ameri, MD, Long V. Dinh, PhD, Raja Rajalingam, PhD, Jerry S. Powell, MD, John Blangero, PhD, Laura Almasy, PhD, Shelley Cole, PhD, Tom E. Howard

Blood (2018) 132 (Supplement 1): 1199.

https://doi.org/10.1182/blood-2018-99-120021

Published: 2018

Journal Articles

The Role of Immune-Response Gene Variants in Inhibitor Development in Black Patients with Hemophilia A.

Tom E. Howard, MD, PhD, Shelley A. Cole, PhD, Carol K. Kasper, MD, Afshin Ameri, MD, Kavita Natarajan, MD, Raymond G. Watts, MD, Valrie A. Manard, RN, Shelley M. Nakaya, Christine L Kempton, MD, MSc, Martina Kennedy, DO, Benjamin Kim, MD, Rathi V. Iyer, MD, Laura Almasy, PhD

Blood (2009) 114 (22): 1301.

https://doi.org/10.1182/blood.V114.22.1301.1301

Published: 2009

Journal Articles

Heritability of Commonly Measured Blood Cell Phenotypes in the San Antonio Family Heart Study.

Kevin R. Viel, PhD, Tom Howard, PhD, MD, Joanne E. Curran, PhD, Laura Almasy, PhD, Eric K. Moses, PhD, David C. Glahn, PhD, Afshin Ameri, MD, Blangero John, PhD

Blood (2007) 110 (11): 3687.

https://doi.org/10.1182/blood.V110.11.3687.3687

Published: 2007

Journal Articles

Potential Spectrum of Missense and Nonsense Factor (F)VIII Gene (F8) Alleles Based on Single Nucleotide Substitutions - How Many Remain To Be Identified?.

Kevin R. Viel, BS, Manana Khachidze, MD, PhD, MPH, Laura Almasy, PhD, Arthur R. Thompson, MD, PhD, Tom E. Howard, MD, PhD

Blood (2006) 108 (11): 4039.

https://doi.org/10.1182/blood.V108.11.4039.4039

Published: 2006

Journal Articles

Allelically Mismatched Replacement Therapy Due to Common African−Restricted Haplotypes of the Factor (F)VIII Protein May Underlie the Increased Incidence of FVIII Inhibitors Observed in Hemophilia−A Patients of African−Descent.

Tom E. Howard, MD, PhD, Kevin R. Viel, BS, Karl M. Fernstrom, BS, Seema Deshpande, PhD, Afshin Ameri, MD, M. Showkat Ali, PhD, Cynthia Channell, BS, Rathi V. Iyer, MD, Raymond G. Watts, MD, Charles Lutcher, MD, Shelley Nakaya, BS, Carol K. Kasper, MD, Arthur R. Thompson, MD, PhD, Thomas C. Abshire, MD, Laura Almasy, PhD

Blood (2006) 108 (11): 765.

https://doi.org/10.1182/blood.V108.11.765.765

Published: 2006

Journal Articles

The Pharmacogenetics and Inhibitor Risk (PIR) Study: Establishing the Spectrum of Factor (F)VIII Gene (F8) Mutations in African-American Hemophilia A Patients.

Tom E. Howard, MD, PhD, Deepa K. Machiah, BS, Kevin R. Viel, PhD, Cynthia Channel, BS, Afshin Ameri, MD, Rathi V. Iyer, MD, Ray G. Watts, MD, Charles Lutcher, MD, Joanna Davis, MD, Thomas C. Abshire, MD, Laura Almasy, PhD

Blood (2005) 106 (11): 3207.

https://doi.org/10.1182/blood.V106.11.3207.3207

Published: 2005

Journal Articles

Effect of F7 Gene Promoter Polymorphisms on Factor VII Antigenic Levels.

Amparo Santamaria, MD, Maria Sabater-Leal, Jose Soria, PhD, Elisabeth Martinez-Marchan, Laura Almasy, PhD, John Blangero, PhD, Jordi Fontcuberta, PhD

Blood (2004) 104 (11): 3962.

https://doi.org/10.1182/blood.V104.11.3962.3962

Published: 2004

Journal Articles

A Quantitative Trait Locus for Cholesterol/Low Density Lipoprotein within the Promoter of the Factor IX Gene.

Kevin R. Viel, BS, Manana Khachidze, MD, PhD, MPH, Alfonso Buil, BS, José Manuel Soria, PhD, Juan Carlos Souto, MD, PhD, Jordi Fontcuberta, MD, PhD, Francisco Blanco-Vaca, MD, PhD, Jordi Ordoñez-Llanos, MD, PhD, Laura Almasy, PhD, Howard Tom, MD, PhD

Blood (2004) 104 (11): 4000.

https://doi.org/10.1182/blood.V104.11.4000.4000

Published: 2004

NARROW

On the Role of F8 Sequence Mismatch and Class-II Human Leukocyte Antigen Binding in the Development of Neutralizing Antibodies ("Inhibitors") Directed Against Therapeutic Factor VIII Proteins (tFVIIIs): Evidence from the PATH Study

Genetics of Factor VIII Inhibitor Development in Hemophilia Patients: Novel Statistical Approaches in the PATH Study

The Role of Immune-Response Gene Variants in Inhibitor Development in Black Patients with Hemophilia A.

Heritability of Commonly Measured Blood Cell Phenotypes in the San Antonio Family Heart Study.

Potential Spectrum of Missense and Nonsense Factor (F)VIII Gene (F8) Alleles Based on Single Nucleotide Substitutions - How Many Remain To Be Identified?.

Allelically Mismatched Replacement Therapy Due to Common African−Restricted Haplotypes of the Factor (F)VIII Protein May Underlie the Increased Incidence of FVIII Inhibitors Observed in Hemophilia−A Patients of African−Descent.

The Pharmacogenetics and Inhibitor Risk (PIR) Study: Establishing the Spectrum of Factor (F)VIII Gene (F8) Mutations in African-American Hemophilia A Patients.

Effect of F7 Gene Promoter Polymorphisms on Factor VII Antigenic Levels.

A Quantitative Trait Locus for Cholesterol/Low Density Lipoprotein within the Promoter of the Factor IX Gene.

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American Society of Hematology

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American Society of Hematology

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