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Journal Articles

A Mouse Homolog of Mutant Wasp Responsible for X-Linked Neutropenia Causes Reduced Myeloid Progenitor Activity but Rather Increased Neutrophil Compartment in Bone Marrow

Masahiro Ikeda, Muneyoshi Futami, MD PhD, Bidisha Chanda, MD PhD, Masayuki Kobayashi, MD PhD, Kiyoko Izawa, PhD, Arinobu Tojo, MD PhD

Blood (2020) 136 (Supplement 1): 39–40.

https://doi.org/10.1182/blood-2020-139059

Published: 2020

Journal Articles

Forced HoxB4 Sustains CD45 - c-kit + Pre-Hematopoieitc Stem Cells (HSCs) Derived from Murine Induced-Pluripotent Stem Cells, Which Develop Long-Term and Short-Term Repopulating HSCs According to GATA2 Expression Level

Kiyoko Izawa, PhD, Tomoya Kakegawa, Master, Masayuki Yamamoto, MD PhD, Arinobu Tojo, MD PhD

Blood (2014) 124 (21): 1567.

https://doi.org/10.1182/blood.V124.21.1567.1567

Published: 2014

Journal Articles

Long-Term Ex Vivo Maintenance Of Murine iPSC-Derived Hematopoietic Stem/Progenitor Cells By Conditional HoxB4

Kiyoko Izawa, PhD, Masayuki Yamamoto, MD, PhD, Arinobu Tojo, MD, PhD.

Blood (2013) 122 (21): 2418.

https://doi.org/10.1182/blood.V122.21.2418.2418

Published: 2013

Journal Articles

Unique Role of mTOR Inhibitor, Everolimus in Inducible Regulatory T Cells

Tokiko Nagamura-Inoue, MD, PhD., Yuki Yamamoto, MT., Seiichiro Kobayashi, MD, PhD, Kazuo Ogami, Kiyoko Izawa, PhD, Miki Yuzawa, MT., Hajime Tsunoda, MD, PhD., Arinobu Tojo, MD, PhD.

Blood (2012) 120 (21): 4349.

https://doi.org/10.1182/blood.V120.21.4349.4349

Published: 2012

Journal Articles

The in Vitro and In Vivo Oncogenic Activity of Homodimeric Mutant of Interleukin-7 Receptor a Chain (IL7Rα) Highlights the Significance of the IL7Rα/Jak1 Pathway in T-Cell Acute Lymphoblastic Leukemia

Kazuaki Yokoyama, MD, Nozomi Yokoyama, Kiyoko Izawa, PhD, Ai Kotani, MD, PhD, Ratanakanit Harnprasopwat, PhD, Akira Harashima, MD, PhD, Seiichiro Kobayashi, MD, PhD, Arinobu Tojo, MD, PhD

Blood (2011) 118 (21): 73.

https://doi.org/10.1182/blood.V118.21.73.73

Published: 2011

Journal Articles

The Significance of mTOR Inhibitor, Everolimus in TGF-β-Induced Regulatory T cells from Cord Blood

Tokiko Nagamura-Inoue, Seiichiro Kobayashi, MD, PhD, Kazuo Ogami, Yuki Yamamoto, Kiyoko Izawa, PhD, Arinobu Tojo, MD, PhD

Blood (2011) 118 (21): 2180.

https://doi.org/10.1182/blood.V118.21.2180.2180

Published: 2011

Journal Articles

Bcr-Abl Impairs T Cell Development From Murine Induced Pluripotent Stem Cells and Hematopoietic Stem Cells; A Partial Explanation for the Concept That Ph+ Clone Never Involves T Cell Lineage in CML,

Bidisha Chanda, MBBS, Kiyoko Izawa, PhD, Ratanakanit Harnprasopwat, PhD, Keisuke Takahashi, Seiichiro Kobayashi, MD, PhD, Yumi Kanegae, PhD, Izumu Saito, PhD, Arinobu Tojo, MD, PhD

Blood (2011) 118 (21): 3748.

https://doi.org/10.1182/blood.V118.21.3748.3748

Published: 2011

Journal Articles

Leukemogenic Fusion Gene (p190 BCR-ABL) Transduction Into Hematopoietic Stem/Progenitor Cells In the Common Marmoset

Yamin Tian, MD, Yan Dong, MD, PhD, Seiichiro Kobayashi, MD, PhD, Manabu Ozawa, PhD, Kiyoko Izawa, PhD, Yuansong Bai, MD, PhD, Yasushi Soda, MD, PhD, Erika Sasaki, PhD, Toshio Itoh, PhD, Naoki Oyaizu, MD, PhD, Satoshi Takahashi, Arinobu Tojo, MD, PhD, Chieko Kai, PhD, Kenzaburo Tani, MD, PhD

Blood (2010) 116 (21): 4323.

https://doi.org/10.1182/blood.V116.21.4323.4323

Published: 2010

Journal Articles

Hormone-Conditional Activation of Bcr-Abl Kinase Highlights Stat5 Anti-Apoptotic Pathway Prior to Promoting Cell Growth.

Ratanakanit Harnprasopwat, Naoyuki Takahashi, MD, PhD, Seiichiro Kobayashi, MD, PhD, Kazuaki Yokoyama, MD, Kiyoko Izawa, PhD, Ai Kotani, MD, PhD, Toshio Kitamura, MD, PhD, Arinobu Tojo, MD, PhD

Blood (2010) 116 (21): 3380.

https://doi.org/10.1182/blood.V116.21.3380.3380

Published: 2010

Journal Articles

Development of a Unique In Vitro and In Vivo Model System of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph-ALL) with Emphasis on Cell to Cell Interaction.

Arinobu Tojo, MD, PhD, Kiyoko Izawa, PhD, Rieko Sekine, MD, Tokiko Nagamura-Inoue, MD,PhD, Seiichiro Kobayashi, MD,PhD

Blood (2006) 108 (11): 1845.

https://doi.org/10.1182/blood.V108.11.1845.1845

Published: 2006

Journal Articles

Leptomycin B Overcomes Imatinib Resistance Mediated by Stromal Cells and Mutant BCR-ABL in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Cells.

Arinobu Tojo, MD, PhD, Kiyoko Izawa, PhD, Rieko Sekine, Tokiko Nagamura, MD, PhD, Minoru Yoshida, PhD, Takashi Tsuji, PhD

Blood (2004) 104 (11): 2089.

https://doi.org/10.1182/blood.V104.11.2089.2089

Published: 2004

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A Mouse Homolog of Mutant Wasp Responsible for X-Linked Neutropenia Causes Reduced Myeloid Progenitor Activity but Rather Increased Neutrophil Compartment in Bone Marrow

Forced HoxB4 Sustains CD45 - c-kit + Pre-Hematopoieitc Stem Cells (HSCs) Derived from Murine Induced-Pluripotent Stem Cells, Which Develop Long-Term and Short-Term Repopulating HSCs According to GATA2 Expression Level

Long-Term Ex Vivo Maintenance Of Murine iPSC-Derived Hematopoietic Stem/Progenitor Cells By Conditional HoxB4

Unique Role of mTOR Inhibitor, Everolimus in Inducible Regulatory T Cells

The in Vitro and In Vivo Oncogenic Activity of Homodimeric Mutant of Interleukin-7 Receptor a Chain (IL7Rα) Highlights the Significance of the IL7Rα/Jak1 Pathway in T-Cell Acute Lymphoblastic Leukemia

The Significance of mTOR Inhibitor, Everolimus in TGF-β-Induced Regulatory T cells from Cord Blood

Bcr-Abl Impairs T Cell Development From Murine Induced Pluripotent Stem Cells and Hematopoietic Stem Cells; A Partial Explanation for the Concept That Ph+ Clone Never Involves T Cell Lineage in CML,

Leukemogenic Fusion Gene (p190 BCR-ABL) Transduction Into Hematopoietic Stem/Progenitor Cells In the Common Marmoset

Hormone-Conditional Activation of Bcr-Abl Kinase Highlights Stat5 Anti-Apoptotic Pathway Prior to Promoting Cell Growth.

Development of a Unique In Vitro and In Vivo Model System of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph-ALL) with Emphasis on Cell to Cell Interaction.

Leptomycin B Overcomes Imatinib Resistance Mediated by Stromal Cells and Mutant BCR-ABL in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Cells.

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