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Kira Young, PhD
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Journal Articles

Decline in Insulin-like Growth Factor-1 (IGF1) from Aged Mesenchymal Stromal Cells Is a Targetable Mechanism to Rescue Hematopoietic Stem Cell Aging

Kira Young, PhD, Elizabeth Eudy, BS, Matthew Loberg, BA, Rebecca Bell, BA, Jennifer Trowbridge, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 526.
https://doi.org/10.1182/blood-2019-124534
Published: 2019
Journal Articles

Cell-Extrinsic Stressors from the Aging Bone Marrow (BM) Microenvironment Promote Dnmt3a -Mutant Clonal Hematopoiesis

Jennifer Myers SanMiguel, PhD, Matthew Loberg, BA, Sarah Heuer, Tim Stearns, Kira Young, PhD, Jennifer Trowbridge, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5.
https://doi.org/10.1182/blood-2019-124511
Published: 2019
Journal Articles

Mutation in DNA Methyltransferase DNMT3A Confers Enhanced Self-Renewal Capacity Onto Multipotent Progenitor Cells and Predisposes to Acute Myeloid Leukemia (AML)

Matthew Loberg, BA, Rebecca Bell, BA, Tim Stearns, Leslie Goodwin, Kira Young, PhD, David Bergstrom, Rebekka Schneider, MD PhD, Jennifer J. Trowbridge, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2569.
https://doi.org/10.1182/blood-2018-99-111560
Published: 2018
Journal Articles

The Middle-Aged Bone Marrow Microenvironment Drives Hematopoietic Stem Cell Aging through Altered Production of Insulin-like Growth Factor-1 (IGF1)

Kira Young, PhD, Matthew Loberg, BA, Elizabeth Eudy, BS, Rebecca Bell, BA, Jennifer J. Trowbridge, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5091.
https://doi.org/10.1182/blood-2018-99-111055
Published: 2018
Journal Articles

Decreased IGF-1 Expression in the Bone Marrow Microenvironment Drives Hematopoietic Aging

Kira Young, PhD, Matthew Loberg, BA, Rebecca Bell, BA, Jennifer J. Trowbridge, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2440.
https://doi.org/10.1182/blood.V130.Suppl_1.2440.2440
Published: 2017