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Kevin R. Gillinder, PhD
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Journal Articles

Gene Editing of KLF1 to Cure Sickle Cell Disease

Kevin R. Gillinder, PhD, Casie Leigh Reed, BSc, Shezlie Malelang, BSc, Helen Lorraine Mitchell, BSc, Emma Hoskin, BSc, Graham William Magor, BSc, Zane Kaplan, MBBS(Hons) BMedSc(Hons) PhDFRACP FRCPA, Andrew Charles Perkins, MBBS,PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30–31.
https://doi.org/10.1182/blood-2020-142339
Published: 2020
Journal Articles

KLF1 Acts As a Pioneer Transcription Factor to Open Chromatin and Facilitate Recruitment of GATA1

Kevin R. Gillinder, PhD, Graham Magor, BSc, Charles Bell, BSc, Melissa D. Ilsley, BSc PhD, Stephen Huang, BSc, Andrew Perkins, MBBS, PhD, FRCPA, FRACP
Journal: Blood
Blood (2018) 132 (Supplement 1): 501.
https://doi.org/10.1182/blood-2018-99-119608
Published: 2018
Journal Articles

A Potential Role for Genes within the mTORC1 Pathway in the Regulation of Embryonic Globin Expression Revealed By ChIP-Seq, RNA-Seq and eQTL Mapping in the Nan Anemia Mouse Model

Danitza M. Nebor, PhD, Joel H. Graber, PhD, Kevin R. Gillinder, PhD, Melissa D. Ilsley, BSc, Raymond F. Robledo, PhD, Steven L. Ciciotte, MS, Vivek Philip, PhD, James J. Bieker, PhD, Andrew C Perkins, PhD, Luanne L. Peters, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2203.
https://doi.org/10.1182/blood.V130.Suppl_1.2203.2203
Published: 2017
Journal Articles

Fine-Tuning Erythropoiesis By Competition Between Krüppel-like Factors for Promoters and Enhancers

Melissa Ilsley, BSc, Kevin R. Gillinder, PhD, Graham Magor, MB BS (Hons), Merlin Crossley, DPhil, Andrew C Perkins, PhD
Journal: Blood
Blood (2016) 128 (22): 1036.
https://doi.org/10.1182/blood.V128.22.1036.1036
Published: 2016
Journal Articles

Mutations in the Second Linker of KLF1 Cause Congenital Non-Spherocytic Hemolytic Anemia Due to Global Reduction of In Vivo DNA-Binding Affinity

Stephen Huang, B Sc (Hons), Kevin R. Gillinder, PhD, Annabel Sorolla, PhD, Emma Whitelaw, BSc PhD, Andrew C Perkins, PhD
Journal: Blood
Blood (2016) 128 (22): 1246.
https://doi.org/10.1182/blood.V128.22.1246.1246
Published: 2016
Journal Articles

Direct Targets of Epo Receptor-JAK2-pSTAT5 Signalling in Erythropoiesis

Kevin R. Gillinder, PhD, Hugh Tuckey, BSc (Hons), Charles Bell, BSc, Stephen Huang, B Sc (Hons), Melissa Ilsley, BSc, Graham Magor, MB BS (Hons), Andrew C Perkins, PhD
Journal: Blood
Blood (2016) 128 (22): 3881.
https://doi.org/10.1182/blood.V128.22.3881.3881
Published: 2016
Journal Articles

Identifying Novel Modifiers of Embryonic Globin Expression By Combining Chipseq, Rnaseq and eQTL Mapping in the Adult Nan Mouse Model

Danitza Nebor, PhD, Kevin R. Gillinder, PhD, Raymond F. Robledo, PhD, Joel H. Graber, PhD, Vivek Philip, PhD, Melissa Ilsley, BSc, James J. Bieker, PhD, Andrew Perkins, PhD, Luanne L. Peters, PhD
Journal: Blood
Blood (2016) 128 (22): 398.
https://doi.org/10.1182/blood.V128.22.398.398
Published: 2016
Journal Articles

Characterisation of Novel Hypomorphic and Null Mutations in Klf1 Derived from a Genetic Screen for Modifiers of a -Globin Transgene Variegation

Stephen Huang, B Sc (Hons), Kevin R. Gillinder, PhD, Melissa Ilsley, BSc, Graham Magor, MB BS (Hons), Michael Tallack, MDPhD, Anabel Sorolla, B Sc PhD, Harald Oey, BSc PhD, Sarah Harten, BSc PhD, Lucia Clemens-Daxinger, BSc PhD, Emma Whitelaw, BSc PhD, Andrew C Perkins, MDPhD
Journal: Blood
Blood (2015) 126 (23): 3329.
https://doi.org/10.1182/blood.V126.23.3329.3329
Published: 2015
Journal Articles

Degenerate DNA Binding By Mutant (E339D) KLF1 Dramatically Alters the Erythroid Transcriptome in the Nan Mouse Model

Danitza Nebor, PhD, Raymond F. Robledo, PhD, Joel H. Graber, PhD, Omorose Aighewi, Lionel Blanc, PhD, Andrew C Perkins, Kevin R. Gillinder, PhD, James J. Bieker, PhD, Luanne L. Peters, PhD
Journal: Blood
Blood (2015) 126 (23): 932.
https://doi.org/10.1182/blood.V126.23.932.932
Published: 2015