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Kelly A Frazer, Ph.D.
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Journal Articles

The Role Of CD44 Isoform Expression In Niche Resident Chronic Myeloid Leukemia Stem Cell Evolution

Cayla Mason, BSc, Frida Holm, PhD, Eva Hellqvist, PhD, Christian Barrett, PhD, Kelly A Frazer, Ph.D., Anil Sadarangani, PhD, Catriona HM Jamieson, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4028.
https://doi.org/10.1182/blood.V122.21.4028.4028
Published: 2013
Journal Articles

Inhibition Of Inflammation Driven Leukemia Stem Cell Self-Renewal With a Selective JAK2 Antagonist

Angela C Court Recart, BS, MS, Anil Sadarangani, PhD, Elizabeth Chun, MSc, Cayla N Mason, BS, Qingfei Jiang, PhD, Christian L Barrett, Ph.D., Russell Wall, BS, Daniel J Goff, PhD, Ifat Geron, MSc, Alice Shih, Heather S. Leu, B.S., Wenxue Ma, M.D., Ph.D., Mark D. Minden, MD PhD, Kelly A Frazer, Ph.D., Marco A. Marra, PhD, Leslie A Crews, PhD, Catriona HM Jamieson, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1481.
https://doi.org/10.1182/blood.V122.21.1481.1481
Published: 2013
Journal Articles

Genomic Analysis of Serial Chronic Lymphocytic Leukemia Samples Suggests That Epigenetic Changes, Rather Than Clonal Evolution, May Drive the Progression of This Leukemia

Emanuela M. Ghia, PhD, Erin Smith, PhD, Christopher DeBoever, Laura Z. Rassenti, Ph.D., Sophie Rozenzhak, Peter Shepard, PhD, Hakan Alakus, M.D., Olivier Harismendy, PhD, Christian L Barrett, Ph.D., Kelly A Frazer, Ph.D., Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 4563.
https://doi.org/10.1182/blood.V120.21.4563.4563
Published: 2012
Journal Articles

Sabutoclax, a Novel Pan BCL2 Family Inhibitor, Sensitizes Dormant Blast Crisis Chronic Myeloid Leukemia Stem Cells to Dasatinib

Heather S. Leu, B.S., Daniel J Goff, PhD, Janine Low-Marchelli, PhD, Angela C Court Recart, BS, MS, Kristen M. Smith, Ph.D., Wenxue Ma, M.D., Ph.D., Anil Sadarangani, Ph.D., Alice Y. Shih, B.S., Jun Wei, Ph.D., Dayong Zhai, Ph.D., Jason Gotlib, M.D., M.S., Mark D. Minden, MD, PhD, Giovanni Martinelli, MD, Marco A. Marra, PhD, Kelly A Frazer, Ph.D., Maurizio Pellecchia, PhD, John C. Reed, MD, PhD, Catriona Jamieson, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3739.
https://doi.org/10.1182/blood.V120.21.3739.3739
Published: 2012
Journal Articles

The RNA Editase ADAR1 Promotes Malignant Progenitor Reprogramming in Chronic Myeloid Leukemia.

Qingfei Jiang, Ph.D., Leslie Crews-Robertson, PhD, Christian L Barrett, Ph.D., Hyn-June Chun, Angela C. Court-Recart, M.S., Daniel J Goff, PhD, Mark D. Minden, MD, PhD, Anil Sadarangani, Ph.D., Jessica Rusert, B.S., Kim-Hien Dao, DO, PhD, Sheldon R Morris, MD, MPH, Lawrence S. B. Goldstein, Ph.D., Marco A. Marra, PhD, Kelly A Frazer, Ph.D., Catriona Jamieson, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2772.
https://doi.org/10.1182/blood.V120.21.2772.2772
Published: 2012
Journal Articles

Combined JAK/STAT5A and BCR-ABL Inhibition Impairs Blast Crisis Chronic Myeloid Leukemia Stem Cell Self-Renewal

Angela C Court Recart, BS, MS, Daniel J Goff, PhD, Anil Sadarangani, Ph.D., Cayla N Mason, BS, Alice Y. Shih, B.S., Russell Wall, BS, Heather S. Leu, B.S., Wenxue Ma, M.D., Ph.D., Hye-Jung Chun, MSc, Marco A. Marra, PhD, Christian L Barrett, Ph.D., Kelly A Frazer, Ph.D., Catriona Jamieson, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 910.
https://doi.org/10.1182/blood.V120.21.910.910
Published: 2012
Journal Articles

Combination Targeted Therapy to Impair Self-Renewal Capacity of Human Blast Crisis Leukemia Stem Cells

Angela C Court Recart, BS, MS, Anil Sadarangani, Ph.D., Daniel Goff, BS, Alice Y Shih, BS, Russell Wall, BS, Heather Leu, BS, Wenxue Ma, M.D., Ph.D., Christian L Barrett, Ph.D., Kelly A Frazer, Ph.D., Elizabeth Chun, MSc, Marco A. Marra, PhD, Catriona Jamieson, MD, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 1693.
https://doi.org/10.1182/blood.V118.21.1693.1693
Published: 2011
Journal Articles

BCL2 Splice Isoform Switching Promotes Leukemia Stem Cell Survival and Sensitivity to a Novel Pan BCL2 Inhibitor

Daniel Goff, BS, Kristen M Smith, Ph.D., Alice Y Shih, BS, Angela Court-Recart, MS, Anil Sadarangani, Ph.D., Ifat Geron, MSc, Ryan Chuang, Larisa Balaian, Ph.D., Jun Wei, Ph.D., Shinichi Kitada, Ph.D., Dayong Zhai, Ph.D., Jason Gotlib, MD, MS, Mark D. Minden, MD, PhD, Giovanni Martinelli, MD, Annelie Schairer, Ph.D., Heather Leu, BS, Wenxue Ma, MD, PhD, Qingfei Jiang, Ph.D., Jessica Rusert, B.S., Kim-Hien T Dao, D.O., Ph.D., Kamran Shazand, PhD, Milica Volar, Richard de Borja, John D McPherson, PhD, Thomas J Hudson, MD, Christian L Barrett, Ph.D., Kelly A Frazer, Ph.D., Peggy Wentworth, Ph.D., Christina Jamieson, Ph.D., Sheldon R Morris, MD, MPH, Lawrence S. B. Goldstein, Ph.D., Maurizio Pellechia, Ph.D., John C. Reed, MD, PhD, Catriona Jamieson
Journal: Blood
Blood (2011) 118 (21): 2735.
https://doi.org/10.1182/blood.V118.21.2735.2735
Published: 2011
Journal Articles

Cycling Toward Leukemia Stem Cell Elimination Wtih a Selective Sonic Hedgehog Antagonist,

Alice Y Shih, BS, Annelie Schairer, Ph.D., Christian L Barrett, Ph.D., Ifat Geron, MSc, Angela C Court Recart, BS, MS, Daniel Goff, BS, Sacha Prashad, Jerry Wu, PharmD, Qingfei Jiang, PhD, Jason Gotlib, MD, MS, Larisa Balaian, Ph.D., Mark D. Minden, MD, PhD, Heather Leu, BS, Russell Wall, BS, Wenxue Ma, M.D., Ph.D., Kamran Shazand, PhD, John D McPherson, PhD, Steven M. Kornblau, MD, Ida Deichaite, PhD, Minya Pu, PhD, Lei Bao, PhD, Giovanni Martinelli, MD, Tannishtha Reya, PhD, Sheldon R Morris, MD, MPH, Todd VanArsdale, PhD, Thomas J Hudson, MD, Karen Messer, PhD, Hanna Mikkola, MD, PhD, Wendy J. Levin, MD, MS, Kelly A Frazer, Ph.D., Anil Sadarangani, Ph.D., Catriona Jamieson, MD, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 3776.
https://doi.org/10.1182/blood.V118.21.3776.3776
Published: 2011