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Katharina Rothe, PhD
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Journal Articles

Targeting AXL Kinase Sensitizes Acute Myeloid Leukemia Stem and Progenitor Cells to Venetoclax Treatment

Katharina Rothe, PhD, Xiaojia Niu, PhD, Min Chen, PhD, Rick Li, Sungeun Nam, Xiuyan Zhang, German Novakovskiy, Yehyeon Ahn, Shenshen Lai, Hong Zhang, PhD, Jun Yan, Hong Liu, Yun Zhao, PhD, Depei Wu, MDPhD, Yubin Ge, PhD, Wyeth W. Wasserman, Calvin K. Yip, Zaihui Zhang, PhD, Xiaoyan Jiang, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 20.
https://doi.org/10.1182/blood-2020-140595
Published: 2020
Journal Articles

Inhibition of the MiR-185-PAK6-Mediated Survival and Metabolic Pathways Selectively Targets Drug-Resistant CML Stem/Progenitor Cells

Andrew Wu, BSc, Katharina Rothe, PhD, Min Chen, PhD, Hanyang Lin, PhD, Artem Babaian, PhD, Ryan Yen, BSc, Donna L. Forrest, MD, Xiaoyan Jiang, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4138.
https://doi.org/10.1182/blood-2019-127826
Published: 2019
Journal Articles

Global Transcriptome Profiling Identifies a Key Mir-185-PAK6 Axis That Promotes Survival of Leukemic Stem Cells and Drug-Insensitive Blasts in BCR-ABL + Human Leukemia

Andrew Wu, BSc, Lin Hanyang, PhD, Katharina Rothe, PhD, Min Chen, MD PhD, Jens Ruschmann, PhD, Oleh Petriv, PhD, Kieran O'Neill, PhD, Tobias Maetzig, MD, David Knapp, PhD, Naoto Nakamichi, MD PhD, Ryan Brinkman, PhD, Inanc Birol, PhD, Donna L Forrest, MD, Carl Hansen, PhD, R. Keith Humphries, MD PhD, Connie J. Eaves, PhD, Xiaoyan Jiang, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 931.
https://doi.org/10.1182/blood-2018-99-113559
Published: 2018
Journal Articles

Inhibiting the Core Autophagy Enzyme ATG4B with Novel Drugs Sensitizes Resistant Leukemic Stem/Progenitor Cells to Standard Targeted Therapy

Katharina Rothe, PhD, Akie Watanabe, Donna L. Forrest, MD, Sharon Gorski, PhD, Robert Young, PhD, Xiaoyan Jiang, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 933.
https://doi.org/10.1182/blood-2018-99-117309
Published: 2018
Journal Articles

Drug-Insensitive CML Stem/Progenitor Cells Highly Express Key Regulators of the Hedgehog Pathway and Inhibition of the Hedgehog Pathway Enhances Their Response to TKI Treatment

Kelly A. Turner, BSc, Katharina Rothe, PhD, Adrian Woolfson, MD PhD, Xiaoyan Jiang, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4236.
https://doi.org/10.1182/blood.V128.22.4236.4236
Published: 2016
Journal Articles

Enhanced and Accelerated Repopulation of Mutant C-Kit Immunodeficient Mice By Transplants of Primary Chronic and Acute Myeloid Leukemic Human Cells

Naoto Nakamichi, MD PhD, Colin A. Hammond, Paul H. Miller, PhD, Katharina Rothe, PhD, Philip A Beer, BM, MRCP, MRCPath, Xiaoyan Jiang, MD PhD, Michael W. Deininger, MD PhD, Connie J. Eaves, PhD
Journal: Blood
Blood (2016) 128 (22): 4537.
https://doi.org/10.1182/blood.V128.22.4537.4537
Published: 2016
Journal Articles

The Focal Adhesion Complex Ilk-Pinch-Parvin Is Key to Niche Interactions and Survival of Quiescent Stem Cells in Chronic Myeloid Leukemia In Vitro and In Vivo

Katharina Rothe, PhD, Artem Babaian, Naoto Nakamichi, MD PhD, Min Chen, PhD, Akie Watanabe, Dixie Mager, PhD, Connie J. Eaves, PhD, Shoukat Dedhar, PhD, Xiaoyan Jiang, MD PhD
Journal: Blood
Blood (2016) 128 (22): 936.
https://doi.org/10.1182/blood.V128.22.936.936
Published: 2016