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Jun Chen, PhD
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Journal Articles

Expression of Bcl-2 Pro-Survival Family Proteins Predicts Pharmacological Responses to ABT-199, a Novel and Selective Bcl-2 Antagonist, in Multiple Myeloma Models

Deepak Sampath, PhD, Elizabeth Punnoose, PhD, Erwin R. Boghaert, PhD, Lisa Belmont, PhD, Jun Chen, PhD, Franklin Peale, MD, PhD, Nguyen Tan, Walter Darbonne, Peng Yue, PhD, Jason Oeh, Leslie Lee, Wayne J. Fairbrother, PhD, Andrew J. Souers, PhD, Steve W. Elmore, PhD, Joel D. Leverson, PhD
Journal: Blood
Blood (2012) 120 (21): 5028.
https://doi.org/10.1182/blood.V120.21.5028.5028
Published: 2012
Journal Articles

Activity of Bruton's Tyrosine Kinase (Btk) Inhibitor PCI-32765 in Mantle Cell Lymphoma (MCL) Identifies Btk As a Novel Therapeutic Target,

Sabine Ponader, PhD, Sriram Balasubramanian, PhD, Lan V Pham, PhD, Jun Chen, PhD, Archito T. Tamayo, MS, Michael Wang, MD, Susan O'Brien, MD, William G. Wierda, MD, PhD, Michael J Keating, MD, Richard J. Ford, MD, PhD, Jan A. Burger, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 3688.
https://doi.org/10.1182/blood.V118.21.3688.3688
Published: 2011
Journal Articles

The Bruton's Tyrosine Kinase (BTK) Inhibitor PCI-32765 Inhibits Growth of ABC DLBCL Tumors In Vivo and in Vitro by Preventing Activation of Pro-Survival NF-κB pathways

Sriram Balasubramanian, PhD, Richard Crowley, MS, Mint Sirisawad, MS, Patti Thiemann, MS, Jun Chen, PhD, Joseph J. Buggy, PhD
Journal: Blood
Blood (2011) 118 (21): 4969.
https://doi.org/10.1182/blood.V118.21.4969.4969
Published: 2011
Journal Articles

The Bcl-2 Family Protein Inhibitor, ABT-263, Promotes Apoptotic-Like Response in Isolated Platelets.

Chris Tse, PhD, Haichao Zhang, PhD, Jun Chen, PhD, Ryan M. Fryer, PhD, Richard Nelson, Paul Nimmer, Glenn A. Reinhart, PhD, Morey L. Smith, Stephen K. Tahir, PhD, Saul H. Rosenberg, PhD, Steven W. Elmore, PhD
Journal: Blood
Blood (2006) 108 (11): 1122.
https://doi.org/10.1182/blood.V108.11.1122.1122
Published: 2006
Journal Articles

Motexafin Gadolinium Enhances Rituximab-Induced Cytotoxicity Against B-Cell Lymphoma Cell Lines: Role of Elevated Intracellular Calcium.

Jun Chen, PhD, Jason Ramos, PhD, Mint Sirisawad, BS, Richard A. Miller, MD, Louie Naumovski, MD-PhD
Journal: Blood
Blood (2005) 106 (11): 4829.
https://doi.org/10.1182/blood.V106.11.4829.4829
Published: 2005
Journal Articles

Growth Inhibition or Apoptosis after Treatment with Motexafin Gadolinium and Celecoxib Is Cell Line Dependent and Correlates with p27 Levels.

Jason Ramos, PhD, Mint Sirisawad, BS, Jun Chen, PhD, Richard A. Miller, MD, Louie Naumovski, MD-PhD
Journal: Blood
Blood (2005) 106 (11): 4296.
https://doi.org/10.1182/blood.V106.11.4296.4296
Published: 2005
Journal Articles

Motexafin Gadolinium Enhances Rituximab-Induced Cytotoxicity Against B-Cell Lymphoma Cell Lines.

Jun Chen, PhD, Jason Ramos, PhD, Mint Sirisawad, BA, Richard A. Miller, MD, Louie Naumovski, MD-PhD
Journal: Blood
Blood (2004) 104 (11): 2296.
https://doi.org/10.1182/blood.V104.11.2296.2296
Published: 2004
Journal Articles

Motexafin Gadolinium Induces Apoptosis in Lymphoid Cell Lines and Demonstrates Enhanced Biological Activity with Akt Kinase Inhibitors.

Louie Naumovski, MD-PhD, Jason Ramos, PhD, Jun Chen, PhD, Mint Sirisawad, BA, David Lucas, PhD, John C. Byrd, MD, Richard A. Miller, MD
Journal: Blood
Blood (2004) 104 (11): 3406.
https://doi.org/10.1182/blood.V104.11.3406.3406
Published: 2004