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Journal Articles

Investigating Potential Mechanism(s) By Which ASO-Based Drugs Cause Thrombocytopenia

Martina H. Lundberg Slingsby, PhD, Genevieve Couldwell, Prakrith Vijey, Brooke E Terkovich, Leila Noetzli, PhD, Ross Okazaki, Jonathan N. Thon, PhD, Scott P. Henry, PhD, Padmakumar Narayanan, DVM, PhD, Joseph E. Italiano, Jr., PhD

Blood (2018) 132 (Supplement 1): 3747.

https://doi.org/10.1182/blood-2018-99-116590

Published: 2018

Journal Articles

Aspirin Inhibits Platelets from Reprogramming Breast Tumor Cells and Promoting Metastasis

Kellie Machlus, PhD, Kelly Johnson, PhD, Julia Ceglowski, Jodi Forward, Mason Tippy, Saleh El-Husayni, Rajesh Kulenthirarajan, Wendy Chen, MD, Joseph E. Italiano, Jr., PhD, Elisabeth Battinelli, MD PhD

Blood (2017) 130 (Supplement 1): 3629.

https://doi.org/10.1182/blood.V130.Suppl_1.3629.3629

Published: 2017

Journal Articles

Tamoxifen Directly Inhibits Platelet Activation, Angiogenic Potential and Platelet-Mediated Metastasis

Elisabeth M. Battinelli, MD PhD, Kelly Elizabeth Johnson, PhD, Jodi A Forward, Mason Tippy, BS, Rajesh Kulenthirarajan, Erica L. Mayer, MD, Joseph E Italiano, Jr., PhD

Blood (2016) 128 (22): 3723.

https://doi.org/10.1182/blood.V128.22.3723.3723

Published: 2016

Journal Articles

CCL5 Released from Platelets Increases Megakaryocyte Maturation and Proplatelet Formation

Kellie R Machlus, PhD, Kelly Elizabeth Johnson, PhD, Rajesh Kulenthirarajan, Saleh El-Husayni, Jodi A Forward, Stephen K Wu, Joseph E Italiano, Jr., PhD, Elisabeth M. Battinelli, MD PhD

Blood (2015) 126 (23): 1162.

https://doi.org/10.1182/blood.V126.23.1162.1162

Published: 2015

Journal Articles

Functionally Distinct Cell Populations Characterize Cord Blood Derived Megakaryocytes

Cory Lindsay, Seema Bhatlekar, Raul Teruel-Montoya, Lin Ma, Martha Sola-Visner, MD, Joseph E Italiano, Jr., PhD, Leonard C. Edelstein, PhD, Paul F. Bray, MD

Blood (2015) 126 (23): 4754.

https://doi.org/10.1182/blood.V126.23.4754.4754

Published: 2015

Journal Articles

Platelets Promote Breast Cancer Metastasis By Reprogramming Tumor Cells to Produce IL-8

Kelly Elizabeth Johnson, PhD, Kellie R Machlus, PhD, Saleh El-Husayni, Rajesh Kulenthirarajan, Jodi A Forward, Joseph E Italiano, Jr., PhD, Elisabeth M. Battinelli, MD PhD

Blood (2015) 126 (23): 2233.

https://doi.org/10.1182/blood.V126.23.2233.2233

Published: 2015

Journal Articles

Anticoagulation Inhibits Tumor Cell-Mediated Release Of Platelet Angiogenic Proteins and Disrupts The Platelet Angiogenic Potential

Elisabeth M. Battinelli, MD, PhD, Beth A. Markens, Rajesh Kulenthirarajan, B.S., Kellie R Machlus, PhD, Robert Flaumenhaft, M.D. Ph.D, Joseph E. Italiano, Jr., PhD

Blood (2013) 122 (21): 2303.

https://doi.org/10.1182/blood.V122.21.2303.2303

Published: 2013

Journal Articles

Anticoagulation Agents Inhibit Physiological and Pathological Release of Angiogenic Regulatory Proteins From Platelets Usurping the Innate Angiogenic Potential of Platelets.

Elisabeth M. Battinelli, MD, PhD, Beth A. Markens, Rajesh Kulenthirarajan, B.S., Joseph E. Italiano, Jr., PhD

Blood (2012) 120 (21): 2174.

https://doi.org/10.1182/blood.V120.21.2174.2174

Published: 2012

Journal Articles

New α-Granule Biology Reveals How Platelets May Regulate Angiogenesis

Joseph E. Italiano, Jr., PhD, Elisabeth M. Battinelli, MD, PhD

Blood (2012) 120 (21): SCI-35.

https://doi.org/10.1182/blood.V120.21.SCI-35.SCI-35

Published: 2012

Journal Articles

Megaloblastic Anemia and Mitochondriopathy Caused by a Homozygous Mutation in Sideroflexin-4.

Jeffrey D. Cooney, Gordon J. Hildick-Smith, Caterina Garone, M.D., Jonathan N. Thon, Ph.D., Orhan H. Akman, Ph.D., Caiyong Chen, Ph.D., Dhvanit I. Shah, Ph.D., Diana Santos Branco, M. Sc., Non Miyata, Ph.D., Matthew L. Freedman, M.D., Sarah E. Calvo, Ph.D., Vamsi K. Mootha, M.D., Carla M. Koehler, Ph.D., Joseph E. Italiano, Jr., PhD, M. Alice Donati, M.D., Salvatore DiMauro, M.D., Barry H. Paw, M.D., Ph.D.

Blood (2012) 120 (21): 79.

https://doi.org/10.1182/blood.V120.21.79.79

Published: 2012

Journal Articles

Protein Synthesis and Degradation in the Late Stages of Megakaryocyte Maturation Trigger Proplatelet Formation

Kellie R Machlus, PhD, Dallas Shi, PhD, Andrew S Weyrich, PhD, Joseph E Italiano, Jr., PhD

Blood (2012) 120 (21): 1218.

https://doi.org/10.1182/blood.V120.21.1218.1218

Published: 2012

Journal Articles

MKL2 Functions in the Absence of MKL1 to Promote Megakaryocyte Maturation

Elenoe C Smith, Jonathan Noah Thon, Ph.D., Stephanie Ann Massaro, MD, MPH, Joseph E. Italiano, Jr., PhD, Diane Krause, MD, PhD

Blood (2011) 118 (21): 2336.

https://doi.org/10.1182/blood.V118.21.2336.2336

Published: 2011

Journal Articles

The Functional Role of TLR9 in Human Platelets

Jonathan Noah Thon, Ph.D., Christian G. Peters, Ph.D., Rukhsana Aslam, Ph.D., Jesse Rowley, Ph.D., Andrew S. Weyrich, Ph.D., John W. Semple, PhD, Robert C. Flaumenhaft, MD, PhD, Joseph E. Italiano, Jr., PhD

Blood (2011) 118 (21): 366.

https://doi.org/10.1182/blood.V118.21.366.366

Published: 2011

Journal Articles

Anti-Coagulation Agents Provide a Mechanism to Inhibit Tumor Cells From Hijacking the Angiogenic Potential of Platelets

Elisabeth M. Battinelli, MD, PhD, Beth Markens, Joseph E. Italiano, Jr., PhD

Blood (2011) 118 (21): 1149.

https://doi.org/10.1182/blood.V118.21.1149.1149

Published: 2011

Journal Articles

The Neuronal Protein GAP-43 Associates with Microtubules and Lipid Rafts in Platelets and Megakaryocytes and Is Involved in Platelet Genesis

Antonija Jurak Begonja, PhD, Lilly Nguyen, Joseph E. Italiano, Jr., PhD, Herve Falet, PhD, Karina F. Meiri, PhD, John H. Hartwig, PhD

Blood (2011) 118 (21): 2201.

https://doi.org/10.1182/blood.V118.21.2201.2201

Published: 2011

Journal Articles

Size Limits the Ability of Platelets to Undergo Abcission

Jonathan Noah Thon, Ph.D., Hannah Macleod, Antonija Jurak Begonja, PhD, Jie Zhu, Ph.D., Kun-Chun Lee, Ph.D., Alex Mogilner, Ph.D., John H. Hartwig, PhD, Joseph E. Italiano, Jr., PhD

Blood (2011) 118 (21): 4821.

https://doi.org/10.1182/blood.V118.21.4821.4821

Published: 2011

Journal Articles

Thrombocytopenia and Cardiomyopathy ( trac ): A New Single Gene Mutation Resulting in Severe Platelet and Heart Abnormalities in Mice.

Leonard D. Shultz, PhD, Bonnie L. Lyons, DVM, Roderick T. Bronson, DVM, Leah Rae Donahue, PhD, Lisa M. Burzenski, BS, Bruce Gott, Belinda S. Harris, BS, Joseph E. Italiano, Jr., PhD, Kenneth R. Johnson, PhD

Blood (2005) 106 (11): 734.

https://doi.org/10.1182/blood.V106.11.734.734

Published: 2005

NARROW

Investigating Potential Mechanism(s) By Which ASO-Based Drugs Cause Thrombocytopenia

Aspirin Inhibits Platelets from Reprogramming Breast Tumor Cells and Promoting Metastasis

Tamoxifen Directly Inhibits Platelet Activation, Angiogenic Potential and Platelet-Mediated Metastasis

CCL5 Released from Platelets Increases Megakaryocyte Maturation and Proplatelet Formation

Functionally Distinct Cell Populations Characterize Cord Blood Derived Megakaryocytes

Platelets Promote Breast Cancer Metastasis By Reprogramming Tumor Cells to Produce IL-8

Anticoagulation Inhibits Tumor Cell-Mediated Release Of Platelet Angiogenic Proteins and Disrupts The Platelet Angiogenic Potential

Anticoagulation Agents Inhibit Physiological and Pathological Release of Angiogenic Regulatory Proteins From Platelets Usurping the Innate Angiogenic Potential of Platelets.

New α-Granule Biology Reveals How Platelets May Regulate Angiogenesis

Megaloblastic Anemia and Mitochondriopathy Caused by a Homozygous Mutation in Sideroflexin-4.

Protein Synthesis and Degradation in the Late Stages of Megakaryocyte Maturation Trigger Proplatelet Formation

MKL2 Functions in the Absence of MKL1 to Promote Megakaryocyte Maturation

The Functional Role of TLR9 in Human Platelets

Anti-Coagulation Agents Provide a Mechanism to Inhibit Tumor Cells From Hijacking the Angiogenic Potential of Platelets

The Neuronal Protein GAP-43 Associates with Microtubules and Lipid Rafts in Platelets and Megakaryocytes and Is Involved in Platelet Genesis

Size Limits the Ability of Platelets to Undergo Abcission

Thrombocytopenia and Cardiomyopathy ( trac ): A New Single Gene Mutation Resulting in Severe Platelet and Heart Abnormalities in Mice.

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American Society of Hematology

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American Society of Hematology

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