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Journal Articles

Outcomes of Down-Syndrome Associated Acute Lymphoblastic Leukemia in Adults: A Single Center Retrospective Review

Sita D. Bhella, MD, Eshetu G Atenafu, M.Sc., P.Stat., Joseph Brandwein, MD FRCPC, Vikas Gupta, MD FRCP, FRCPath, Johann Hitzler, MD FRCP (C), FAAP, Dina Khalaf, BSc, MSc, MD, Andrzej Lutynski, MD, Aaron D. Schimmer, MD PhD, Andre C Schuh, MD FRCPC, Amr Rostom, MD, Anna Rydlewski, MD, Karen W.L. Yee, MD, Mark D. Minden, MD PhD

Blood (2015) 126 (23): 3717.

https://doi.org/10.1182/blood.V126.23.3717.3717

Published: 2015

Journal Articles

Incidence of Catheter-Related Venous Thromboembolism Events in Acute Leukemia patients ; A Comparative, Retrospective Study of the Safety of Peripherally-Inserted Vs Centrally-Inserted Central Venous Catheters

Mohammad Refaei, MD BSc, MSc, Bruna Fernandes, Joseph Brandwein, MD FRCPC, M. Dawn Goodyear, MD, Cynthia M Wu, MD FRCPC

Blood (2015) 126 (23): 3546.

https://doi.org/10.1182/blood.V126.23.3546.3546

Published: 2015

Journal Articles

Discordance Between Morphologic and Cytogenetic Findings Following Induction Chemotherapy for Acute Myeloid Leukemia Is Prevalent in Patients with Bone Marrow Blasts >2% and Is Associated with Poor Clinical Outcomes

Lalit Saini, MD, Joseph Brandwein, MD FRCPC, Irwindeep Sandhu, MD

Blood (2015) 126 (23): 4978.

https://doi.org/10.1182/blood.V126.23.4978.4978

Published: 2015

Journal Articles

Antithymocyte Globulin at Clinically Relevant Concentration Kills Leukemic Blasts

Rosy Dabas, Rachelle Lee, Maria Theresa Servito, Poonam Dharmani Khan, Monica Modi, MD, Tiffany Van Slyke, Joanne Luider, Caylib Durand, Loree Larratt, MD, Joseph Brandwein, MD FRCPC, Andrew Daly, MD FRCPC, Faisal M Khan, PhD D (ABHI), Jan Storek, MD PhD

Blood (2015) 126 (23): 5481.

https://doi.org/10.1182/blood.V126.23.5481.5481

Published: 2015

Journal Articles

Bone Marrow Aspirates Alone without a Trephine Biopsy May be Insufficient for the Detection of Residual Leukemia Following Intensive Chemotherapy for the Treatment of Acute Myeloid Leukemia

Lalit Saini, MD, Robert Turner, MD, Loree Larratt, MD, Joseph Brandwein, MD, Marlene Ann Hamilton, MD, Anthea Peters, MD MSc, FRCPC, Cynthia M Wu, MD FRCPC, Nancy Zhu, MD, Jeffery M. Patterson, MD, Lauren Bolster, MD, Michael Mant, MD, Bruce Ritchie, MD, Elena Liew, MD, Imran Mirza, MD FRCPC, Graeme R. Quest, MDMSc, Susan Nahirniak, Sunita Gosh, PhD, P.Stat., P.Stat, Irwindeep Sandhu, MD FRCPC

Blood (2014) 124 (21): 2336.

https://doi.org/10.1182/blood.V124.21.2336.2336

Published: 2014

Journal Articles

The FLAG Chemotherapy Regimen Is an Alternative to Anthracycline Based Therapy for the Treatment of Acute Myeloid Leukemia for Patients with Multiple Co-Morbidities or Preexisting Cardiac Disease

Lalit Saini, MD, Robert Turner, MD, Loree Larratt, MD, Joseph Brandwein, MD, Marlene Ann Hamilton, MD, Anthea Peters, MD MSc, FRCPC, Cynthia M. Wu, MD FRCPC, Nancy Zhu, MD, Jeffery M. Patterson, MD, Lauren Bolster, MD, Michael Mant, MD, Bruce Ritchie, MD, Elena Liew, MD, Imran Mirza, MD FRCPC, Graeme R. Quest, MDMSc, Sunita Gosh, PhD, P.Stat., P.Stat, Irwindeep Sandhu, MD FRCPC

Blood (2014) 124 (21): 961.

https://doi.org/10.1182/blood.V124.21.961.961

Published: 2014

Journal Articles

A Phase II Study Of Aprepitant As Anti-Emetic Prophylaxis In Patients Receiving Induction Chemotherapy For AML

Joseph Brandwein, MD, FRCPC, Karen W.L. WL Yee, MD, Andre C Schuh, MD, Vikas Gupta, MD, FRCP, FRCPath, Jack T Seki, PharmD

Blood (2013) 122 (21): 5035.

https://doi.org/10.1182/blood.V122.21.5035.5035

Published: 2013

Journal Articles

Azacitidine Has Limited Activity in Patients with MDS and AML

Karen Yee, MD, Symron Bansal, Joseph Brandwein, MD, Mark D. Minden, MD, Aaron Schimmer, MD, PhD, Vikas Gupta, MD, FRCP, FRCPath, Arsenia Dharman, Christine Cserti-Gazdewich, MD, Andre Schuh, MD, FRCPC

Blood (2011) 118 (21): 5057.

https://doi.org/10.1182/blood.V118.21.5057.5057

Published: 2011

Journal Articles

Pre-Screening for Low Methyl Guanine Methyltransferase (MGMT) Expression Results in High Response Rates to Temozolomide (TMZ) Therapy in AML and MDS Patients.

Joseph Brandwein, MD, Jeannine Kassis, MD, Brian Leber, MD, Kang Howson-Jan, MD, Mark D. Minden, MD, Andre Galarneau, Jean-Francois Pouliot, PhD

Blood (2011) 118 (21): 422.

https://doi.org/10.1182/blood.V118.21.422.422

Published: 2011

Journal Articles

An Evaluation of Septicemia During Outpatient Consolidation Chemotherapy for Acute Myeloid Leukemia

Lalit Saini, MD, Mark D. Minden, MD, PhD, Andre Schuh, MD, Karen Yee, MD, Aaron D Schimmer, MD, PhD, Vikas Gupta, MD, FRCP, FRCPath, Cindy Susan Murray, Joseph Brandwein, MD

Blood (2011) 118 (21): 4268.

https://doi.org/10.1182/blood.V118.21.4268.4268

Published: 2011

Journal Articles

Identification of AML and MDS Patients Who Could Potentially Benefit From Temozolomide Therapy: Proportion of Patients with Low Methyl Guanine Methyltransferase (MGMT) Expression Level

Joseph Brandwein, MD, Jeannine Kassis, MD, Brian Leber, MD, Kang Howson-Jan, MD, Mark D. Minden, MD, PhD, Kim Greaves, BSc, RN, DESS, Jean-Francois Pouliot, PhD

Blood (2010) 116 (21): 3985.

https://doi.org/10.1182/blood.V116.21.3985.3985

Published: 2010

Journal Articles

A Phase I Study of ENMD-2076 In Patients with Relapsed or Refractory Leukemia

Karen W.L. Yee, MD, Hsaio-Wei Tina Chen, Joseph Brandwein, MD, FRCPC, Sue Chow, Deborah Sanfelice, David Hedley, MD, Vikas Gupta, MD, MRCP, FRCPath, Aaron Schimmer, MD, PhD, Carolyn Fowler Sidor, MD, Graham Fletcher, Jamie Arnott, Mark Bray, Mark D. Minden, MD, PhD, Andre Schuh, MD, FRCPC

Blood (2010) 116 (21): 3307.

https://doi.org/10.1182/blood.V116.21.3307.3307

Published: 2010

Journal Articles

A Prognostic Score of Overall Survival In Adults with Acute Myeloid Leukemia

Murtadha K. Al-Khabori, MD, FRCPC, Gordon Guyatt, MD, FRCPC, Mark D. Minden, MD, PhD, Karen Yee, MD, Vikas Gupta, MD, MRCP, FRCPath, Aaron Schimmer, MD, PhD, Andre Schuh, MD, FRCPC, Joseph Brandwein, MD, FRCPC

Blood (2010) 116 (21): 2730.

https://doi.org/10.1182/blood.V116.21.2730.2730

Published: 2010

Journal Articles

Validation of Monosomal Karyotype Based Model In the Risk Stratification of Acute Myeloid Leukemia

Murtadha K. Al-Khabori, MD, FRCPC, Karen Yee, MD, Vikas Gupta, MD, MRCP, FRCPath, Aaron Schimmer, MD, PhD, Andre Schuh, MD, FRCPC, Mark D. Minden, MD, PhD, Joseph Brandwein, MD, FRCPC

Blood (2010) 116 (21): 2745.

https://doi.org/10.1182/blood.V116.21.2745.2745

Published: 2010

Journal Articles

Low-Level FLT3-ITD Mutations Do Not Predict for Higher Relapse Rate in AML with Standard Risk Karyotpye.

Richard Ward, BSc, MRCP, FRCPath, Suzanne Kamel-Reid, PhD, FACMG, Wei Xu, PhD, Mark D. Minden, MD, PhD, Aaron D. Schimmer, MD, PhD, Karen WL Yee, MD, Andre Schuh, MD, Vikas Gupta, MD, Joseph Brandwein, MD

Blood (2009) 114 (22): 1591.

https://doi.org/10.1182/blood.V114.22.1591.1591

Published: 2009

Journal Articles

A Prospective Study of Voriconazole Therapeutic Drug Monitoring (TDM) in Patients with Acute Leukemia.

Jack Seki, PharmD, Joseph Brandwein, MD, Richard Ward, BSc, MRCP, FRCPath, Narinder Paul, MD, Heather Russell, MD, Deepali Kumar, MD

Blood (2009) 114 (22): 1018.

https://doi.org/10.1182/blood.V114.22.1018.1018

Published: 2009

Journal Articles

Lack of Inhibition of AKT Predicts Clinical Resistance to Therapy with Imatinib + Reinduction Chemotherapy in Relapsed/Refractory c-Kit+ Acute Myeloid Leukemia.

Joseph Brandwein, MD, David Hedley, MD, Sue Chow, Aaron D. Schimmer, MD, PhD, Karen WL Yee, Andre Schuh, MD, Vikas Gupta, Mark D. Minden, MD, PhD

Blood (2009) 114 (22): 2073.

https://doi.org/10.1182/blood.V114.22.2073.2073

Published: 2009

Journal Articles

Feasibility of Outpatient Consolidation Chemotherapy and Toxicity in Elderly Patients with AML.

Richard Ward, BSc, MRCP, FRCPath, Vikas Gupta, MD, Mark D. Minden, MD, PhD, Aaron D. Schimmer, MD, PhD, Karen WL Yee, MD, Andre Schuh, MD, Wei Xu, PhD, Joseph Brandwein, MD

Blood (2009) 114 (22): 1036.

https://doi.org/10.1182/blood.V114.22.1036.1036

Published: 2009

Journal Articles

Outcome of Patients Age 60 and Over with Acute Lymphoblastic Leukemia (ALL) Treated with a Modified Pediatric Protocol

Susan Kao, MD, Wei Xu, PhD, Vikas Gupta, MD, MRCP, MRCPath, Mark Minden, Andre Schuh, MD, Aaron D. Schimmer, Karen WL Yee, Joseph Brandwein, MD, FRCPC

Blood (2008) 112 (11): 3962.

https://doi.org/10.1182/blood.V112.11.3962.3962

Published: 2008

Journal Articles

A Phase II Study of Lenalidomide in Previously Untreated, Symptomatic Chronic Lymphocytic Leukemia (CLL).

Christine I. Chen, MD, Harminder Paul, Pantoja Mariela, Joseph Brandwein, MD, Vishal Kukreti, MD, Suzanne Trudel, MD, Ellen Wei, Jieffei Tong, Mike Moran

Blood (2007) 110 (11): 2042.

https://doi.org/10.1182/blood.V110.11.2042.2042

Published: 2007

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Outcomes of Down-Syndrome Associated Acute Lymphoblastic Leukemia in Adults: A Single Center Retrospective Review

Incidence of Catheter-Related Venous Thromboembolism Events in Acute Leukemia patients ; A Comparative, Retrospective Study of the Safety of Peripherally-Inserted Vs Centrally-Inserted Central Venous Catheters

Discordance Between Morphologic and Cytogenetic Findings Following Induction Chemotherapy for Acute Myeloid Leukemia Is Prevalent in Patients with Bone Marrow Blasts >2% and Is Associated with Poor Clinical Outcomes

Antithymocyte Globulin at Clinically Relevant Concentration Kills Leukemic Blasts

Bone Marrow Aspirates Alone without a Trephine Biopsy May be Insufficient for the Detection of Residual Leukemia Following Intensive Chemotherapy for the Treatment of Acute Myeloid Leukemia

The FLAG Chemotherapy Regimen Is an Alternative to Anthracycline Based Therapy for the Treatment of Acute Myeloid Leukemia for Patients with Multiple Co-Morbidities or Preexisting Cardiac Disease

A Phase II Study Of Aprepitant As Anti-Emetic Prophylaxis In Patients Receiving Induction Chemotherapy For AML

Azacitidine Has Limited Activity in Patients with MDS and AML

Pre-Screening for Low Methyl Guanine Methyltransferase (MGMT) Expression Results in High Response Rates to Temozolomide (TMZ) Therapy in AML and MDS Patients.

An Evaluation of Septicemia During Outpatient Consolidation Chemotherapy for Acute Myeloid Leukemia

Identification of AML and MDS Patients Who Could Potentially Benefit From Temozolomide Therapy: Proportion of Patients with Low Methyl Guanine Methyltransferase (MGMT) Expression Level

A Phase I Study of ENMD-2076 In Patients with Relapsed or Refractory Leukemia

A Prognostic Score of Overall Survival In Adults with Acute Myeloid Leukemia

Validation of Monosomal Karyotype Based Model In the Risk Stratification of Acute Myeloid Leukemia

Low-Level FLT3-ITD Mutations Do Not Predict for Higher Relapse Rate in AML with Standard Risk Karyotpye.

A Prospective Study of Voriconazole Therapeutic Drug Monitoring (TDM) in Patients with Acute Leukemia.

Lack of Inhibition of AKT Predicts Clinical Resistance to Therapy with Imatinib + Reinduction Chemotherapy in Relapsed/Refractory c-Kit+ Acute Myeloid Leukemia.

Feasibility of Outpatient Consolidation Chemotherapy and Toxicity in Elderly Patients with AML.

Outcome of Patients Age 60 and Over with Acute Lymphoblastic Leukemia (ALL) Treated with a Modified Pediatric Protocol

A Phase II Study of Lenalidomide in Previously Untreated, Symptomatic Chronic Lymphocytic Leukemia (CLL).

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