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Jose Luis Lopez Lorenzo, MD
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Journal Articles

Lentiviral Mediated Gene Therapy for Pyruvate Kinase Deficiency: A Global Phase 1 Study for Adult and Pediatric Patients

José Luis López Lorenzo, MD, Susana Navarro, PhD, Ami J Shah, MD, Maria Grazia Roncarolo, MD, Julián Sevilla, MD PhD, Lucía Llanos, MD PhD, Begoña Pérez Camino de Gaisse, MD, Sol Sanchez, MD, Bertil Glader, MD PhD, May Chien, MD, Oscar Quintana Bustamante, PhD, Brian C Beard, PhD, Kenneth M Law, PhD, Miriam Zeini, PhD, Grace Choi, BS, Eileen Nicoletti, MD, Juan A Bueren, PhD, Gayatri R Rao, MD JD, Jonathan D Schwartz, MD, José C Segovia, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 47.
https://doi.org/10.1182/blood-2020-137246
Published: 2020
Journal Articles

Frequency, Clinical Characteristics and Outcome of Adult Patients with Acute Lymphoblastic Leukemia (ALL) and COVID-19 in Spain: Results of a Survey from Pethema and Geth Groups

Josep-Maria Ribera, Mireia Morgades, M.Prob.S, Rosa Coll, MD, Jose Luis Lopez Lorenzo, MD, Pau Montesinos, MD PhD, Rosario Varela, Mónica Cabrero, Ignacio Gómez-Centurión, M. Dolores Morales, MD, Antoni Garcia-Guiñon, MD, Guiomar Bautista, Pilar Herrera Puente, Laura Llorente, Irene García-Cadenas, Pere Barba, MD PhD, Maria Calbacho, MD, Cristina Gil, Maria Angeles Foncillas, María Teresa Artola, MD, Rafael De La Camara, MD, Jose Luis Piñana Sanchez
Journal: Blood
Blood (2020) 136 (Supplement 1): 19.
https://doi.org/10.1182/blood-2020-134296
Published: 2020
Journal Articles

Correction of the Energetic Defects in Pyruvate Kinase Deficiency through Genome Editing in Hematopoietic Stem and Progenitor Cells

Sara Fañanas-Baquero, Oscar Quintana Bustamante, PhD, Daniel P. Dever, PhD, Omaira Alberquilla, Rebeca Sanchez-Dominguez, PhD, Joab Camarena, BS, Rolf Turk, José Luis López Lorenzo, MD, Paola Bianchi, BSc, PhD, Mark Behlke, MD PhD, Juan A Bueren, PhD, Matt Porteus, MD PhD, José C Segovia, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 29.
https://doi.org/10.1182/blood-2020-139117
Published: 2020
Journal Articles

Mutational Profiling Predicts Clinical Outcomes to Azacytidine and Low Dose Cytarabine Plus Fludarabine (FLUGA) in Elderly Acute Myeloid Leukemia Patients Enrolled in the Pethema Phase III Flugaza Trial

Rosa M. Ayala, MD PhD, Inmaculada Rapado, David Martínez-Cuadron, MD, Esther Onecha, PhD, Laura Rufian, Miss, Alexandra Juarez, Juan Bergua Burgues, Susana Vives, MD, Jesús Lorenzo Algarra, Mar Tormo, MD PhD, Pilar Martinez, MD, Josefina Serrano, Pilar Herrera, MD, Fernando Ramos, Olga Salamero, MD, Esperanza Lavilla, Cristina Gil, MD, Jose Luis Lopez Lorenzo, MD, Maria-Belen Vidriales, MD, Jorge Labrador, MD, José F. Falantes, Maria Jose Sayas, Bruno Paiva, PhD, Eva Barragán, Felipe Prosper, MD PhD, Miguel A. Sanz, Joaquin Martinez Lopez, MD PhD, Pau Montesinos Fernandez, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3891.
https://doi.org/10.1182/blood-2019-127187
Published: 2019
Journal Articles

Comparation of Digital PCR and Quantitative Pcr for Molecular Monitorization of Chronic Myeloid Leukemia Patients

Juan Manuel Alonso Dominguez, MD PhD MSc, Rodrigo Iñiguez Garcia, MD, Susana Olmedillas, PhD, Rocio N Salgado, PhD, Tamara Castaño, MD, Carlos Blas, MD, Diego Velasco Rodrgiguez, MD PhD, Gala Vega, MD, Jose Luis Lopez Lorenzo, MD, Pilar Giraldo, PhD, Joaquin Martinez Lopez, MD PhD, Pilar Llamas, MDPhD, Mireia Atance, Arantxa Garcías Raso
Journal: Blood
Blood (2017) 130 (Supplement 1): 2891.
https://doi.org/10.1182/blood.V130.Suppl_1.2891.2891
Published: 2017
Journal Articles

Characterization of Ex-Vivo PTCH1 Expression Under Tyrosine Kinase Inhibitors Treatment and Determination of Downstream Effectors Oh Hedgehog Pathway in CML

Juan Manuel Alonso Dominguez, MD PhD MSc, Alicia Arenas, PhD, Pilar Llamas, MDPhD, Diego Velasco, Aránzazu García-Raso, PhD, Jose Luis Lopez Lorenzo, MD, Mireia Atance, Rocio N Salgado, PhD, Joaquin Martinez Lopez, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5245.
https://doi.org/10.1182/blood.V130.Suppl_1.5245.5245
Published: 2017
Journal Articles

Preliminary Results of the Flugaza Trial: A Phase III Randomized, Open Label Study Comparing Azacytidine Versus Fludarabine and Cytarabine (FLUGA Scheme) in Elderly Patients with Newly Diagnosed Acute Myeloid Leukemia

Pau Montesinos, MD PhD, Susana Vives, MD, Maria P Martinez-Sanchez, MD, Juan Bergua, MD, Lorenzo Algarra, MD, Herrera Pilar, MD, Mar Tormo, MD, Jose-Luis Lopez-Lorenzo, MD, Fernando Ramos, MD, Jose Francisco Falantes, MD, Olga Salamero, MD, Josefina Serrano, MD, Cristina Gil, MD, Maria L Amador, MD, Esperanza Lavilla, MD, Maria J Sayas, MD, Maria Teresa Olave, MD, Belen Vidriales, MD, David Martínez-Cuadrón, MD PhD, Miguel Ángel Sanz, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4036.
https://doi.org/10.1182/blood.V128.22.4036.4036
Published: 2016
Journal Articles

Very Early Molecular Responses During The First Two Months Of Therapy Are Highly Predicitive Of Deep Molecular Responses In Newly-Diagnosed Chronic Myeloid Leukemia In Chronic Phase( CML-CP) Patients Treated Upfront With Nilotinib. The Spanish Substudy Of The ENEST1st Trial

Juan Luis Steegmann, MD, Luis Felipe Casado Montero, MD, PhD, Maria Teresa Gomez-Casares, MD, Maria Rozman, MD, Maria Asunción Echeveste, J Valentin Garcia-Gutierrez, MD, PhD, Jose Luis Sastre, MD, Angel Ramirez Payer, MD, Eduardo Olavarria, MD, Ferran Vall, MD, Blanca Xicoy, MD, PhD, Pilar Giraldo, MD PhD, Eulogio Conde, MD, PhD, Rolando Omar Vallansot, MD, Jose Luis Lopez-Lorenzo, MD, Luis Palomera, MD, Soraya Ruiz, PhD, Laura Casas, Claudia Walasek, Dolors Colomer
Journal: Blood
Blood (2013) 122 (21): 5190.
https://doi.org/10.1182/blood.V122.21.5190.5190
Published: 2013