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Journal Articles

Effect of Intravenous and Oral N-Acetylcysteine Treatment in a Patient with Sickle Cell Disease at Disease Baseline

Hasan Tahsin Ozpolat, MD, Junmei Chen, PhD, Xiaoyun Fu, PhD, Warren Osborn, Jennie Le, BS, Minhua Ling, PhD, Sophie Schmitter, BS, Sarah Ruuska, MPH, Dominic W. Chung, PhD, Barbara A Konkle, José A. López, MD

Blood (2018) 132 (Supplement 1): 4911.

https://doi.org/10.1182/blood-2018-99-117087

Published: 2018

Journal Articles

Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after CD19 CAR-T Cell Immunotherapy

Cameron J. Turtle, MBBS, PhD, Kevin A. Hay, MD FRCPC, MSc, Laila-Aicha Hanafi, PhD, Juliane Gust, MDPhD, W. Conrad Liles, MDPhD, José A. López, MD, Junmei Chen, PhD, Dominic W. Chung, PhD, Mark M Wurfel, MDPhD, Susanna Harju-Baker, PhD, Hasan Ozpolat, MD, Daniel Li, PhD, David Myerson, MDPhD, Luis F. Gonzalez-Cuyar, MD, Cecilia Yeung, MD, Kathleen R. Fink, MD, Stanley R. Riddell, MD, David G. Maloney, MD PhD

Blood (2017) 130 (Supplement 1): 805.

https://doi.org/10.1182/blood.V130.Suppl_1.805.805

Published: 2017

Journal Articles

Platelet Factor 4 Binds to Released Von Willebrand Factor Strands from Injured Endothelium and Forms a Prothrombotic HIT Antigenic Complex

Ian Johnston, BS, Jose A. Lopez, MD, Douglas B. Cines, MD, Lubica Rauova, MD PhD, Mortimer Poncz, MD

Blood (2017) 130 (Supplement 1): 2310.

https://doi.org/10.1182/blood.V130.Suppl_1.2310.2310

Published: 2017

Journal Articles

Effects of N-Acetylcysteine Infusion in Patients with Sickle Cell Disease during Vaso-Occlusive Crises

Hasan Ozpolat, MD, Junmei Chen, PhD, Xiaoyun Fu, PhD, Melissa Dominguez, MA, Jennie Le, BS, Minhua Ling, PhD, Sophie Schmitter, BS, Sarah Ruuska, MPH, Dominic W. Chung, PhD, Jose A. Lopez, MD, Barbara Konkle, MD

Blood (2017) 130 (Supplement 1): 2238.

https://doi.org/10.1182/blood.V130.Suppl_1.2238.2238

Published: 2017

Journal Articles

LDL and HDL Have Opposing Effects on VWF Self-Association

Forrest D Nussdorfer, BS, Nikita Taparia, BS, Shirin Feghhi, Alexander E St. John, MD, José A. López, MD, Dominic W. Chung, PhD

Blood (2017) 130 (Supplement 1): 3601.

https://doi.org/10.1182/blood.V130.Suppl_1.3601.3601

Published: 2017

Journal Articles

Effects of Oral N -Acetylcysteine on Oxidative Stress in Patients with Sickle Cell Disease

Blood (2017) 130 (Supplement 1): 2244.

https://doi.org/10.1182/blood.V130.Suppl_1.2244.2244

Published: 2017

Journal Articles

Ultra-Low Von Willebrand Factor (VWF) Adsorption Under Shear with a Polymer Coating for Blood-Contacting Devices

Wei Yang, PhD, Junmei Chen, PhD, Jennie Le, BS, José A. López, MD

Blood (2017) 130 (Supplement 1): 1024.

https://doi.org/10.1182/blood.V130.Suppl_1.1024.1024

Published: 2017

Journal Articles

Thrombosis and Von Willebrand Factor in Chuvash Polycythemia

Victor R. Gordeuk, MD, Dominic W. Chung, PhD, Binal N. Shah, PhD, Junmei Chen, PhD, Adelina Sergueeva, MD, Galina Miasnikova, MD, Josef T. Prchal, MD, José A. López, MD

Blood (2017) 130 (Supplement 1): 2377.

https://doi.org/10.1182/blood.V130.Suppl_1.2377.2377

Published: 2017

Journal Articles

A Quantitative Assay of In Vivo Cleavage of Von Willebrand Factor By ADAMTS13 Reveals Excessive Cleavage in Type 2B Von Willebrand Disease and Diminished Cleavage in Thrombotic Thrombocytopenic Purpura

Xiaoyun Fu, PhD, Mallory N. Pahl, Yi Wang, PhD, Barbara A. Konkle, MD, Junmei Chen, PhD, Jose A Lopez, MD

Blood (2016) 128 (22): 2532.

https://doi.org/10.1182/blood.V128.22.2532.2532

Published: 2016

Journal Articles

A Pilot Study of High-Dose N-Acetylcysteine Infusion in Patients with Sickle Cell Disease

Hasan Tahsin Ozpolat, MD, Junmei Chen, PhD, Xiaoyun Fu, PhD, Shelby A Cate, BS, Jennie Le, BS, Minhua Ling, PhD, Colette Norby, MS, Dominic W Chung, PhD, Barbara A. Konkle, MD, Jose A. Lopez, MD

Blood (2016) 128 (22): 1299.

https://doi.org/10.1182/blood.V128.22.1299.1299

Published: 2016

Journal Articles

Potential Mechanisms for Enhanced Activity of Von Willebrand Factor in Patients with Sickle Cell Disease

Junmei Chen, PhD, Tahsin Özpolat, MD, Yi Wang, PhD, Colette Norby, MS, Minhua Ling, PhD, Dominic W Chung, PhD, Barbara Konkle, MD, Xiaoyun Fu, PhD, Jose A. Lopez, MD

Blood (2016) 128 (22): 3716.

https://doi.org/10.1182/blood.V128.22.3716.3716

Published: 2016

Journal Articles

VWF Cleavage Products Inhibit Shear-Induced Self-Association

Shirin Feghhi, PhD, Alexander St. John, MD MS, Jeff Harris, Jennie Le, BS, Dominic W Chung, PhD, Junmei Chen, PhD, Jose A. Lopez, MD

Blood (2016) 128 (22): 3718.

https://doi.org/10.1182/blood.V128.22.3718.3718

Published: 2016

Journal Articles

Pursuing Ultra-Low VWF Adsorption for Blood-Contacting Devices Under Shear

Wei Yang, PhD, Junmei Chen, PhD, Jennie Le, BS, Jose A. Lopez, MD

Blood (2016) 128 (22): 2539.

https://doi.org/10.1182/blood.V128.22.2539.2539

Published: 2016

Journal Articles

Evaluation of Cell Types and Morphologies in Sickle Cell Disease with an Imaging Flow Cytometer

Hasan Tahsin Ozpolat, MD, Tim Chang, PhD, Junmei Chen, PhD, Xiaoping Wu, PhD, Colette Norby, MS, Barbara A Konkle, MD, Jose A. Lopez, MD

Blood (2015) 126 (23): 972.

https://doi.org/10.1182/blood.V126.23.972.972

Published: 2015

Journal Articles

Effect of N-Acetyl-L-Cysteine on Cysteine Redox Status in Patients with Thrombotic Thrombocytopenic Purpura: Protein Disulfide Bound Cysteine As a Biomarker of Oxidative Stress

Xiaoyun Fu, PhD, Shelby A Cate, BS, Junmei Chen, PhD, Tahsin Özpolat, MD, Colette Norby, MS, Barbara A Konkle, MD, Jose A. Lopez, MD

Blood (2015) 126 (23): 1044.

https://doi.org/10.1182/blood.V126.23.1044.1044

Published: 2015

Journal Articles

N-Acetylcysteine Treatment in Two Patients with Relapsed Thrombotic Thrombocytopenic Purpura Increased ADAMTS13 Activity, Free Thiol Concentration in Plasma, and Inhibited Platelet Activation

Junmei Chen, PhD, Tahsin Özpolat, MD, Colette Norby, MS, Jennie Le, BS, Minhua Ling, PhD, Shelby A Cate, BS, Dominic W Chung, PhD, Xiaoyun Fu, PhD, Barbara Konkle, MD, Jose A. Lopez, MD

Blood (2015) 126 (23): 239.

https://doi.org/10.1182/blood.V126.23.239.239

Published: 2015

Journal Articles

ADAMTS13 Synergizes with HDL in Preventing Von Willebrand Factor Self-Association Under Shear Stress

Dominic W Chung, PhD, Junmei Chen, PhD, Minhua Ling, PhD, Taisha Doo, BS, Teri Blevens, Barbara A Konkle, MD, Jose A Lopez, MD

Blood (2015) 126 (23): 3451.

https://doi.org/10.1182/blood.V126.23.3451.3451

Published: 2015

Journal Articles

Effects of N-Acetylcysteine in Patients with Sickle Cell Disease

Tahsin Özpolat, MD, Junmei Chen, PhD, Xiaoyun Fu, PhD, Shelby A Cate, BS, Jennie Le, BS, Colette Norby, MS, Barbara A. Konkle, MD, Jose A. Lopez, MD

Blood (2014) 124 (21): 4173.

https://doi.org/10.1182/blood.V124.21.4173.4173

Published: 2014

Journal Articles

Quantitative Analysis of Small Molecular Weight Thiols and Disulfides in Blood from a Sickle Cell Disease Patient Infused with N-Acetyl-L-Cysteine

Shelby A Cate, BS, Tahsin Ozpolat, MD, Junmei Chen, PhD, Colette Norby, MS, Barbara A. Konkle, MD, Jose A. Lopez, MD, Xiaoyun Fu, PhD

Blood (2014) 124 (21): 2662.

https://doi.org/10.1182/blood.V124.21.2662.2662

Published: 2014

Journal Articles

Anti-β2-GPI Antibodies Induce Von Willebrand Factor Release, Modulate Platelet Binding, and Affect VWF Proteolysis

Christopher J. Ng, MD, Keith R. McCrae, MD, Junmei Chen, PhD, Michael Wang, MD, Marilyn J. Manco-Johnson, MD, Dominic W Chung, PhD, Tara C White-Adams, PhD, Jose A Lopez, MD, Jorge A Di Paola, MD

Blood (2014) 124 (21): 1444.

https://doi.org/10.1182/blood.V124.21.1444.1444

Published: 2014

NARROW

Effect of Intravenous and Oral N-Acetylcysteine Treatment in a Patient with Sickle Cell Disease at Disease Baseline

Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after CD19 CAR-T Cell Immunotherapy

Platelet Factor 4 Binds to Released Von Willebrand Factor Strands from Injured Endothelium and Forms a Prothrombotic HIT Antigenic Complex

Effects of N-Acetylcysteine Infusion in Patients with Sickle Cell Disease during Vaso-Occlusive Crises

LDL and HDL Have Opposing Effects on VWF Self-Association

Effects of Oral N -Acetylcysteine on Oxidative Stress in Patients with Sickle Cell Disease

Ultra-Low Von Willebrand Factor (VWF) Adsorption Under Shear with a Polymer Coating for Blood-Contacting Devices

Thrombosis and Von Willebrand Factor in Chuvash Polycythemia

A Quantitative Assay of In Vivo Cleavage of Von Willebrand Factor By ADAMTS13 Reveals Excessive Cleavage in Type 2B Von Willebrand Disease and Diminished Cleavage in Thrombotic Thrombocytopenic Purpura

A Pilot Study of High-Dose N-Acetylcysteine Infusion in Patients with Sickle Cell Disease

Potential Mechanisms for Enhanced Activity of Von Willebrand Factor in Patients with Sickle Cell Disease

VWF Cleavage Products Inhibit Shear-Induced Self-Association

Pursuing Ultra-Low VWF Adsorption for Blood-Contacting Devices Under Shear

Evaluation of Cell Types and Morphologies in Sickle Cell Disease with an Imaging Flow Cytometer

Effect of N-Acetyl-L-Cysteine on Cysteine Redox Status in Patients with Thrombotic Thrombocytopenic Purpura: Protein Disulfide Bound Cysteine As a Biomarker of Oxidative Stress

N-Acetylcysteine Treatment in Two Patients with Relapsed Thrombotic Thrombocytopenic Purpura Increased ADAMTS13 Activity, Free Thiol Concentration in Plasma, and Inhibited Platelet Activation

ADAMTS13 Synergizes with HDL in Preventing Von Willebrand Factor Self-Association Under Shear Stress

Effects of N-Acetylcysteine in Patients with Sickle Cell Disease

Quantitative Analysis of Small Molecular Weight Thiols and Disulfides in Blood from a Sickle Cell Disease Patient Infused with N-Acetyl-L-Cysteine

Anti-β2-GPI Antibodies Induce Von Willebrand Factor Release, Modulate Platelet Binding, and Affect VWF Proteolysis

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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