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John E. Murphy, PhD
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Journal Articles

Adeno-Associated Virus Mediated Delivery of a TFPI Antibody Restores Hemostasis in Mouse Model of Hemophilia

Swapnil Rakhe, MS, Reema Jasuja, PhD, Rajani Shelke, Anagha Sawant, Suryanarayan Somanathan, PhD, John E. Murphy, PhD, Debra D Pittman, MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 3357.
https://doi.org/10.1182/blood-2019-130054
Published: 2019
Journal Articles

Antibodies Against the Erythroferrone N-Terminal Domain Prevent Hepcidin Suppression and Ameliorate Murine Thalassemia

Joao Arezes, BS, MSc, PhD, Niall Foy, Susan Benard, Anagha Sawant, May S Tam, Zachary Maben, Kirsty McHugh, Doris Quinkert, Andrew E Armitage, Sant-Rayn Pasricha, MD PhD, Pei-Jin Lim, Joe Frost, Edward LaVallie, Orla Cunningham, PhD, Matthew Lambert, Debra D Pittman, MS, John E. Murphy, PhD, Simon J Draper, Reema Jasuja, PhD, Alexander Drakesmith
Journal: Blood
Blood (2019) 134 (Supplement_1): 964.
https://doi.org/10.1182/blood-2019-130246
Published: 2019
Journal Articles

Efficacy and Safety in 15 Hemophilia B Patients Treated with the AAV Gene Therapy Vector Fidanacogene Elaparvovec and Followed for at Least 1 Year

Lindsey A. George, MD, Spencer K. Sullivan, MD, John E.J. Rasko, MBBS, PhD, Adam Giermasz, MD PhD, Benjamin J. Samelson-Jones, MD PhD, Jonathan M. Ducore, MD MPH, Jerome M. Teitel, MD FRCPC, Catherine E. McGuinn, MD, Alexa R. Runowski, MS, Fraser Wright, PhD, Xavier M. Anguela, PhD, Katherine A. High, MD, Denis Rybin, PhD, John E. Murphy, PhD, Jeremy Rupon, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3347.
https://doi.org/10.1182/blood-2019-124091
Published: 2019
Journal Articles

A Neutralizing Monoclonal Antibody (PF-06741086) Against Tissue Factor Pathway Inhibitor in Combination with Activated Prothrombin Complex Concentrate Increases Hemostasis in Inhibitor Hemophilia Plasmas without Excessive Thrombin Generation

Swapnil Rakhe, MS, Sheryl Bowley, PhD, John E. Murphy, PhD, Debra D Pittman, MS
Journal: Blood
Blood (2018) 132 (Supplement 1): 3779.
https://doi.org/10.1182/blood-2018-99-119831
Published: 2018
Journal Articles

Efficacy of Anti-TFPI Antibody PF-06741086 Alone and in Combination with Activated Prothrombin Complex Concentrates in Mouse Hemophilia a Bleeding Model

Amey Barakat, Reema Jasuja, PhD, John E. Murphy, PhD, Debra D Pittman, MS
Journal: Blood
Blood (2018) 132 (Supplement 1): 2460.
https://doi.org/10.1182/blood-2018-99-118431
Published: 2018
Journal Articles

The Tissue Factor Pathway Inhibitor Antibody, PF-06741086, Increases Thrombin Generation in Rare Bleeding Disorder and Von Willebrand Factor Deficient Plasmas

Swapnil Rakhe, MS, Sunita R. Patel-Hett, PhD, Sheryl Bowley, PhD, John E. Murphy, PhD, Debra D Pittman, MS
Journal: Blood
Blood (2018) 132 (Supplement 1): 2462.
https://doi.org/10.1182/blood-2018-99-119674
Published: 2018
Journal Articles

Waveform Analysis Extends the Capabilities of aPTT and PT Clotting Assays for Detecting Factor Deficiency and Monitoring Procoagulant Drug Therapy

Lilley Leong, PhD, MS, Xiaoqiao Jiang, BS, Jill Cifrese, MS, John E. Murphy, PhD, Jesper Haaning, PhD, Timothy Myles, PhD
Journal: Blood
Blood (2011) 118 (21): 1205.
https://doi.org/10.1182/blood.V118.21.1205.1205
Published: 2011